Article
Cardiac & Cardiovascular Systems
Flavien Vincent, Julien Ternacle, Tom Denimal, Mylene Shen, Bjorn Redfors, Cedric Delhaye, Matheus Simonato, Nicolas Debry, Basile Verdier, Bahira Shahim, Thibault Pamart, Hugues Spillemaeker, Guillaume Schurtz, Francois Pontana, Vinod H. Thourani, Philippe Pibarot, Eric Van Belle
Summary: TAVR is rapidly expanding its indications, but faces technical challenges and knowledge gaps when dealing with patients with bicuspid aortic valve (BAV). Physicians need to understand the BAV anatomy and TAVR procedure planning comprehensively to guide treatment decisions.
Article
Biotechnology & Applied Microbiology
Roberta Scuoppo, Stefano Cannata, Giovanni Gentile, Caterina Gandolfo, Salvatore Pasta
Summary: This study used finite-element analysis to quantify coronary flow in a patient who underwent TAVR-in-TAVR and found that high implantation depth and device undersize of the second THV can significantly reduce coronary flow. Additionally, a positive correlation was observed between coronary flow and the valve-to-coronary distance.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Tomo Ando, Oluwole Adegbala, Ankita Aggarwal, Luis Afonso, Hisato Takagi, Cindy L. Grines, Alexandros Briasoulis
Summary: The incidence of redo AVI following TAVR is low but associated with high mortality and morbidity, with higher mortality seen in redo SAVR cases.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Soojung Park, Yongwon Cho, Yu-Whan Oh, Minseok Ko, Do-Sun Lim, Cheol Woong Yu, Seong-Mi Park, Mi-Na Kim, Sung Ho Hwang
Summary: The objective of this study was to explore the relationship between spectral computed tomography (CT) measured iodine concentration and strength of aortic valvular calcification (AVC) in patients with aortic valve stenosis (AVS). The study found that iodine concentration was independently associated with the reduction percentage of AVC. Additionally, when an optimal iodine concentration cutoff point was set at 4 mg/mL, it could accurately assess fragile AVC with a reduction percentage greater than 18.5%.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Shinichi Fukuhara, Chan Tran N. Nguyen, Karen M. Kim, Bo Yang, Gorav Ailawadi, Himanshu J. Patel, G. Michael Deeb
Summary: Despite the rapid adoption of transcatheter aortic valve replacement (TAVR), there are limited data on aortic valve reintervention after initial TAVR. A retrospective study reviewed 1487 patients who underwent TAVR and found that 24 (1.6%) required aortic valve reintervention. Most patients were deemed unsuitable for repeat TAVR due to concurrent cardiac procedures, unfavorable anatomy, or endocarditis. Therefore, careful assessment of TAVR repeatability should be considered in the initial TAVR evaluation, especially for younger patients who may require aortic valve reintervention.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Alessandra Francica, Mikhail Dodonov, Filippo Tonelli, Gaetano Paolino, Gabriele Pesarini, Flavio Ribichini, Giuseppe Faggian, Francesco Onorati
Summary: This report describes a rare case of early postoperative fatal ViV-TAVR thrombosis despite adequate anticoagulation in addition to dual antiplatelet therapy.
ANNALS OF THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Michel Pompeu B. O. Sa, Jef Van den Eynde, Matheus Simonato, Luiz Rafael P. Cavalcanti, Ilias P. Doulamis, Viktoria Weixler, Polydoros N. Kampaktsis, Michele Gallo, Pietro L. Laforgia, Konstantin Zhigalov, Arjang Ruhparwar, Alexander Weymann, Philippe Pibarot, Marie-Annick Clavel
Summary: Valve-in-valve transcatheter aortic valve replacement (ViV TAVR) shows lower 30-day mortality, major bleeding, and shorter hospital stay compared to redo surgical aortic valve replacement (redo SAVR), but is associated with higher rates of severe patient-prosthesis mismatch. There is a lack of comparative studies with long-term follow-up results.
JACC-CARDIOVASCULAR INTERVENTIONS
(2021)
Review
Medicine, General & Internal
Lorenzo Braghieri, Simrat Kaur, Christopher K. Black, Paul C. Cremer, Shinya Unai, Samir R. Kapadia, Amgad Mentias
Summary: Transcatheter aortic valve replacement (TAVR) is increasingly used as the main treatment for aortic stenosis compared to surgical aortic valve replacement (SAVR). However, TAVR-related infective endocarditis (TAVR-IE) is expected to be more common in younger patients. Therefore, it is important for clinicians to be familiar with common presentations, major risk factors, diagnostic pitfalls, therapeutic approaches, and prevention of TAVR-IE.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Keti Vitanova, Syed Zaid, Gilbert H. L. Tang, Tsuyoshi Kaneko, Vinayak N. Bapat, Thomas Modine, EXPLANT TAVR Investigators
Summary: In this study, the outcomes of AVR and root replacement after TAVR explantation were compared. The results showed no differences in short-term mortality and morbidities between the two groups, although they had different clinical characteristics.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Alberto Alperi, Josep Rodes-Cabau, Matheus Simonato, Didier Tchetche, Gaetan Charbonnier, Henrique B. Ribeiro, Azeem Latib, Matteo Montorfano, Marco Barbanti, Sabine Bleiziffer, Bjorn Redfors, Mohamed Abdel-Wahab, Abdelhakim Allali, Giuseppe Bruschi, Massimo Napodano, Marco Agrifoglio, Anna Sonia Petronio, Cristina Giannini, Albert Chan, Ran Kornowski, Nili Schamroth Pravda, Matti Adam, Alessandro Iadanza, Stephane Noble, Andrew Chatfield, Magdalena Erlebach, Joerg Kempfert, Timm Ubben, Harindra Wijeysundera, Moritz Seiffert, Thomas Pilgrim, Won-Keun Kim, Luca Testa, David Hildick-Smith, Roberto Nerla, Claudia Fiorina, Christina Brinkmann, Lars Conzelmann, Didier Champagnac, Francesco Saia, Henrik Nissen, Hafid Amrane, Brian Whisenant, Jasmin Shamekhi, Lars Sondergaard, John G. Webb, Danny Dvir
Summary: In a large series of ViV-TAVR procedures, the incidence of periprocedural PPI was relatively low and decreased with the use of new-generation THV systems. Older age, larger THV size, and previous right bundle branch block were associated with an increased risk of PPI. Although there were no significant differences in 30-day mortality between the PPI and no-PPI groups, PPI patients exhibited a trend toward higher mortality risk at follow-up.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Review
Pharmacology & Pharmacy
Harish Sharma, Shazia Afzal, Juergen Leick, Nikos Werner, Sagar N. Doshi, M. Adnan Nadir
Summary: This review aims to provide clinicians with guidance on the optimal antithrombotic strategy post-TAVR, taking into consideration different patient populations and the limitations of existing guidelines.
PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Cardiac & Cardiovascular Systems
Marina Urena, Alec Vahanian, Eric Brochet, Gregory Ducrocq, Bernard Iung, Dominique Himbert
Summary: The clinical use of TMVR using transcatheter aortic valves is limited to patients with failing bioprostheses or rings, and mitral valve disease associated with severe mitral annulus calcification. While valve-in-valve TMVR seems to be a reasonable alternative to surgery for high-risk patients, there is less evidence supporting valve-in-ring and valve-in-mitral annulus calcification interventions.
Article
Cardiac & Cardiovascular Systems
Amgad Mentias, Marwan Saad, Milind Y. Desai, Amar Krishnaswamy, Venu Menon, Phillip A. Horwitz, Samir Kapadia, Mary Vaughan Sarrazin
Summary: The study compared outcomes of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in patients with rheumatic aortic stenosis (AS), as well as TAVR in nonrheumatic AS. The results showed similar mortality rates between TAVR and SAVR for rheumatic AS patients, suggesting that TAVR could be a viable alternative to traditional surgery in this patient population.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Shinichi Fukuhara, Xiaoting Wu, Robert Hawkins, Gorav Ailawadi, Michael Deeb
Summary: This study investigated the implications of surgically managed prosthetic valve endocarditis (PVE) after transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR). The study found that aortic root repair was less frequent in TAVR patients, but the post-TAVR setting was associated with higher mortality.
ANNALS OF THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Neel M. Butala, Raj Makkar, Eric A. Secemsky, Dianne Gallup, Guillaume Marquis-Gravel, Andrzej S. Kosinski, Sreekanth Vemulapalli, Javier A. Valle, Steven M. Bradley, Tarun Chakravarty, Robert W. Yeh, David J. Cohen
Summary: This study used data from the TAVR registry to investigate the association between EPD use and in-hospital stroke in TAVR patients. While the primary analysis did not find a significant association, a secondary analysis showed a modestly lower risk of in-hospital stroke with EPD use. Further large-scale randomized controlled trials are needed to determine whether EPDs provide meaningful clinical benefit for TAVR patients.
