Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes

Modeling of signaling pathways in chondrocytes based on phosphoproteomic and cytokine release data

(2014) I.N. Melas et al.   OSTEOARTHRITIS AND CARTILAGE

Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease

(2013) Steven J. Van Dyken et al.   Annual Review of Immunology

Intraarticular and Systemic Inflammatory Profiles May Identify Patients with Osteoarthritis

(2013) B. J. Heard et al.   JOURNAL OF RHEUMATOLOGY

The effects of nonsteroidal anti-inflammatory drugs on clinical outcomes, synovial fluid cytokine concentration and signal transduction pathways in knee osteoarthritis. A randomized open label trial

(2013) L. Gallelli et al.   OSTEOARTHRITIS AND CARTILAGE

Gene expression profiling of dedifferentiated human articular chondrocytes in monolayer culture

(2013) B. Ma et al.   OSTEOARTHRITIS AND CARTILAGE

Patient-Specific 3D Microfluidic Tissue Model for Multiple Myeloma

(2013) Wenting Zhang et al.   TISSUE ENGINEERING PART C-METHODS

Matrix-Assisted Autologous Chondrocyte Transplantation for Cartilage Regeneration in Osteoarthritic Knees

(2012) Giuseppe Filardo et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Detection of vascular endothelial growth factor (VEGF) in moderate osteoarthritis in a rabbit model

(2012) H. Jansen et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

The role of synovitis in osteoarthritis pathogenesis

(2012) Carla R. Scanzello et al.   BONE

The STAT3-IGFBP5 axis is critical for IL-6/gp130-induced premature senescence in human fibroblasts

(2012) Hirotada Kojima et al.   CELL CYCLE

DNA damage, discoordinated gene expression and cellular senescence in osteoarthritic chondrocytes

(2012) J. Rose et al.   OSTEOARTHRITIS AND CARTILAGE

Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

(2012) B.J.E. de Lange-Brokaar et al.   OSTEOARTHRITIS AND CARTILAGE

Activation of NF-κB/p65 Facilitates Early Chondrogenic Differentiation during Endochondral Ossification

(2012) Marjolein M. J. Caron et al.   PLoS One

Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model

(2012) Anika I Tsuchida et al.   ARTHRITIS RESEARCH & THERAPY

The distribution pattern of critically short telomeres in human osteoarthritic knees

(2012) Maria Harbo et al.   ARTHRITIS RESEARCH & THERAPY

Five-Year Outcome of Characterized Chondrocyte Implantation Versus Microfracture for Symptomatic Cartilage Defects of the Knee

(2011) Johan Vanlauwe et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Osteoarthritic synovial tissue inhibition of proteoglycan production in human osteoarthritic knee cartilage: Establishment and characterization of a long-term cartilage-synovium coculture

(2011) Michiel Beekhuizen et al.   ARTHRITIS AND RHEUMATISM

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

The effect of vascular endothelial growth factor on aggrecan and type II collagen expression in rat articular chondrocytes

(2011) Xuan-yin Chen et al.   RHEUMATOLOGY INTERNATIONAL

Expression of Vascular Endothelial Growth Factor (VEGF) Associated with Histopathological Changes in Rodent Models of Osteoarthritis

(2011) Fumiko Yamairi et al.   Journal of Toxicologic Pathology

Events in Articular Chondrocytes with Aging

(2011) Daniel J. Leong et al.   Current Osteoporosis Reports

Intravenous administration of anti-vascular endothelial growth factor humanized monoclonal antibody bevacizumab improves articular cartilage repair

(2010) Toshihiro Nagai et al.   ARTHRITIS RESEARCH & THERAPY

Focal Cartilage Defects in the Knee Impair Quality of Life as Much as Severe Osteoarthritis

(2009) Stig Heir et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Human osteoarthritic chondrocytes are impaired in matrix metalloproteinase-13 inhibition by IFN-γ due to reduced IFN-γ receptor levels

(2009) R. Ahmad et al.   OSTEOARTHRITIS AND CARTILAGE

Proteome characterization of human articular chondrocytes leads to novel insights in the function of small heat-shock proteins in chondrocyte homeostasis

(2009) S. Lambrecht et al.   OSTEOARTHRITIS AND CARTILAGE

Cartilage homeostasis in health and rheumatic diseases

(2009) Mary B Goldring et al.   ARTHRITIS RESEARCH & THERAPY

Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism

(2008) M B Goldring et al.   ANNALS OF THE RHEUMATIC DISEASES

Decreased lubricin concentrations and markers of joint inflammation in the synovial fluid of patients with anterior cruciate ligament injury

(2008) K. A. Elsaid et al.   ARTHRITIS AND RHEUMATISM

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

The Structure of Glycosaminoglycans and their Interactions with Proteins

(2008) Neha S. Gandhi et al.   Chemical Biology & Drug Design