Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis

Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice

(2012) John S. Lewis et al.   ARTHRITIS AND RHEUMATISM

Acute and late changes in intraarticular cytokine levels following anterior cruciate ligament injury

(2012) Marco Bigoni et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254)

(2012) V.B. Kraus et al.   OSTEOARTHRITIS AND CARTILAGE

Cartilage and bone markers and inflammatory cytokines are increased in synovial fluid in the acute phase of knee injury (hemarthrosis) – a cross-sectional analysis

(2012) P. Swärd et al.   OSTEOARTHRITIS AND CARTILAGE

Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee

(2011) J.S. Lewis et al.   OSTEOARTHRITIS AND CARTILAGE

Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254)

(2011) Jonathan B Catterall et al.   ARTHRITIS RESEARCH & THERAPY

A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee

(2011) Stanley B Cohen et al.   ARTHRITIS RESEARCH & THERAPY

Clinical optical coherence tomography of early articular cartilage degeneration in patients with degenerative meniscal tears

(2010) Constance R. Chu et al.   ARTHRITIS AND RHEUMATISM

Intraarticular injection of anakinra in osteoarthritis of the knee: A multicenter, randomized, double-blind, placebo-controlled study

(2009) X. Chevalier et al.   ARTHRITIS AND RHEUMATISM

Mechanical injury potentiates proteoglycan catabolism induced by interleukin-6 with soluble interleukin-6 receptor and tumor necrosis factor α in immature bovine and adult human articular cartilage

(2009) Yihong Sui et al.   ARTHRITIS AND RHEUMATISM

Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse

(2008) Benjamin D. Ward et al.   ARTHRITIS AND RHEUMATISM

Decreased lubricin concentrations and markers of joint inflammation in the synovial fluid of patients with anterior cruciate ligament injury

(2008) K. A. Elsaid et al.   ARTHRITIS AND RHEUMATISM

Novel synovial fluid recovery method allows for quantification of a marker of arthritis in mice

(2008) D.R. Seifer et al.   OSTEOARTHRITIS AND CARTILAGE