Dose-escalation of human anti-interferon-α receptor monoclonal antibody MEDI-546 in subjects with systemic sclerosis: a phase 1, multicenter, open label study

Pharmacogenomics and Translational Simulations to Bridge Indications for an Anti-Interferon-α Receptor Antibody

(2013) B Wang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

High frequency of corticosteroid and immunosuppressive therapy in patients with systemic sclerosis despite limited evidence for efficacy

(2012) Nicolas Hunzelmann et al.   ARTHRITIS RESEARCH & THERAPY

Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

(2011) B. W. Higgs et al.   ANNALS OF THE RHEUMATIC DISEASES

The Pathogenesis of Systemic Sclerosis

(2011) Tamiko R. Katsumoto et al.   Annual Review of Pathology-Mechanisms of Disease

Mechanistic Modeling of Antigen Sink Effect for Mavrilimumab Following Intravenous Administration in Patients With Rheumatoid Arthritis

(2011) Bing Wang et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Type I interferon system activation and association with disease manifestations in systemic sclerosis

(2010) M.-L. Eloranta et al.   ANNALS OF THE RHEUMATIC DISEASES

Pharmacotherapy of systemic sclerosis

(2010) Arnold E Postlethwaite et al.   EXPERT OPINION ON PHARMACOTHERAPY

Immunotherapy of systemic sclerosis

(2010) Rebecca Manno et al.   Immunotherapy

The uncontrolled clinical trial: scientific, ethical, and practical reasons for being

(2010) Luigi Saccà   Internal and Emergency Medicine

The Application of Target Information and Preclinical Pharmacokinetic/Pharmacodynamic Modeling in Predicting Clinical Doses of a Dickkopf-1 Antibody for Osteoporosis

(2010) A. M. Betts et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Disease-modifying treatment in systemic sclerosis: current status

(2009) Niamh P Quillinan et al.   CURRENT OPINION IN RHEUMATOLOGY

Critical role for constitutive type I interferon signaling in the prevention of cellular transformation

(2008) Hui-min Chen et al.   CANCER SCIENCE

Systemic sclerosis prevalence and comorbidities in the US, 2001–2002

(2008) Don Robinson et al.   CURRENT MEDICAL RESEARCH AND OPINION

Interferons and scleroderma—A new clue to understanding the pathogenesis of scleroderma?

(2008) Luiz Felipe Leomil Coelho et al.   IMMUNOLOGY LETTERS

Type I Interferon: Potential Therapeutic Target for Psoriasis?

(2008) Yihong Yao et al.   PLoS One