Local intra-articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritis

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(2013) L. Pesesse et al.   OSTEOARTHRITIS AND CARTILAGE

In vivo kinematics comparison of fixed- and mobile-bearing total knee arthroplasty during deep knee bending motion

(2012) Xiaojun Shi et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Autophagy activation by rapamycin reduces severity of experimental osteoarthritis

(2011) Beatriz Caramés et al.   ANNALS OF THE RHEUMATIC DISEASES

Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection

(2011) Beatriz Caramés et al.   ARTHRITIS AND RHEUMATISM

Autophagy modulates osteoarthritis-related gene expression in human chondrocytes

(2011) Hiroshi Sasaki et al.   ARTHRITIS AND RHEUMATISM

Osteoarthritis year 2011 in review: biology

(2011) M. Lotz   OSTEOARTHRITIS AND CARTILAGE

Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?

(2011) P.M. van der Kraan et al.   OSTEOARTHRITIS AND CARTILAGE

Articular cartilage mineralization in osteoarthritis of the hip

(2010) Martin Fuerst et al.   BMC MUSCULOSKELETAL DISORDERS

Osteochondral plate angiogenesis: A new treatment target in osteoarthritis

(2010) Laurence Pesesse et al.   JOINT BONE SPINE

Rapamycin induces growth retardation by disrupting angiogenesis in the growth plate

(2010) Óscar Álvarez-García et al.   KIDNEY INTERNATIONAL

Analysis of early changes in the articular cartilage transcriptisome in the rat meniscal tear model of osteoarthritis: pathway comparisons with the rat anterior cruciate transection model and with human osteoarthritic cartilage

(2010) T. Wei et al.   OSTEOARTHRITIS AND CARTILAGE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Calcification of articular cartilage in human osteoarthritis

(2009) M. Fuerst et al.   ARTHRITIS AND RHEUMATISM

Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis

(2009) John D. Cravero et al.   ARTHRITIS AND RHEUMATISM

Cartilage repair in a rat model of osteoarthritis through intraarticular transplantation of muscle-derived stem cells expressing bone morphogenetic protein 4 and soluble flt-1

(2009) Tomoyuki Matsumoto et al.   ARTHRITIS AND RHEUMATISM

Oxidative Stress Inhibits Insulin-like Growth Factor-I Induction of Chondrocyte Proteoglycan Synthesis through Differential Regulation of Phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK Signaling Pathways

(2009) Weihong Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirolimus to replace calcineurin inhibitors? Too early yet

(2009) Paolo Cravedi et al.   LANCET

Autophagy: A lysosomal degradation pathway with a central role in health and disease

(2008) Eeva-Liisa Eskelinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE