Tapping into the endocannabinoid system to ameliorate acute inflammatory flares and associated pain in mouse knee joints

Prostamide F2αreceptor antagonism combined with inhibition of FAAH may block the pro-inflammatory mediators formed following selective FAAH inhibition

(2013) Alessia Ligresti et al.   BRITISH JOURNAL OF PHARMACOLOGY

Anti-inflammatory effects of cannabinoid CB2receptor activation in endotoxin-induced uveitis

(2013) J T Toguri et al.   BRITISH JOURNAL OF PHARMACOLOGY

Differential β-arrestin2 requirements for constitutive and agonist-induced internalization of the CB1 cannabinoid receptor

(2013) Pál Gyombolai et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Endocannabinoid System and Pain

(2012) Josee Guindon et al.   CNS & Neurological Disorders-Drug Targets

The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation

(2012) Niamh Murphy et al.   Journal of Neuroinflammation

An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee

(2012) John P. Huggins et al.   PAIN

Discovery of Prostamide F2α and Its Role in Inflammatory Pain and Dorsal Horn Nociceptive Neuron Hyperexcitability

(2012) Luisa Gatta et al.   PLoS One

Δ9-Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells

(2011) Douglas McHugh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation

(2011) Mireille Alhouayek et al.   FASEB JOURNAL

Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice

(2011) Steven G. Kinsey et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain

(2010) N. Schuelert et al.   OSTEOARTHRITIS AND CARTILAGE

Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis

(2010) Niklas Schuelert et al.   PAIN

Anandamide Suppresses Proliferation and Cytokine Release from Primary Human T-Lymphocytes Mainly via CB2 Receptors

(2010) Maria Teresa Cencioni et al.   PLoS One

Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain

(2009) Kay Ahn et al.   CHEMISTRY & BIOLOGY

Leukocyte trafficking and pain behavioral responses to a hydrogen sulfide donor in acute monoarthritis

(2008) Benjamin Andruski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain

(2008) Penny C. Staton et al.   PAIN

Divergent peripheral effects of pituitary adenylate cyclase-activating polypeptide-38 on nociception in rats and mice

(2008) Katalin Sándor et al.   PAIN

In vivoeffects of CB2receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints

(2007) J J McDougall et al.   BRITISH JOURNAL OF PHARMACOLOGY

The orphan receptor GPR55 is a novel cannabinoid receptor

(2007) E Ryberg et al.   BRITISH JOURNAL OF PHARMACOLOGY