Dendritic cells provide a potential link between smoking and inflammation in rheumatoid arthritis

Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors

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Fate mapping of IL-17-producing T cells in inflammatory responses

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Prevention of autoimmune rheumatic disease: state of the art and future perspectives

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Genetic variants in the prediction of rheumatoid arthritis

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Patients with early rheumatoid arthritis who smoke are less likely to respond to treatment with methotrexate and tumor necrosis factor inhibitors: Observations from the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatology Reg

(2010) Saedis Saevarsdottir et al.   ARTHRITIS AND RHEUMATISM

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

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Rheumatoid arthritis

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Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

(2010) N. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional and phenotypic effects of AhR activation in inflammatory dendritic cells

(2010) Jaishree Bankoti et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: Results from two large early arthritis cohorts

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Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis

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Anti-TNF-α Agents Are Less Effective for the Treatment of Rheumatoid Arthritis in Current Smokers

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Monocyte Derived Interleukin (IL)-23 Is an Important Determinant of Synovial IL-17A Expression in Rheumatoid Arthritis

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Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis

(2009) Hiba Mahdi et al.   NATURE GENETICS

Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-α, Oncostatin M and response to biologic therapies

(2009) Ellen M Moran et al.   ARTHRITIS RESEARCH & THERAPY

Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

(2007) Linh P. Nguyen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

IL-17/Th17 targeting: On the road to prevent chronic destructive arthritis?

(2007) Erik Lubberts   CYTOKINE