Article
Orthopedics
Mastour Saeed Alshahrani, Ravi Shankar Reddy, Faisal Asiri, Jaya Shanker Tedla, Adel Alshahrani, Praveen Kumar Kandakurti, Venkata Nagaraj Kakaraparthi
Summary: This study found a negative correlation between quadriceps endurance and knee joint position sense (JPS) in individuals with knee osteoarthritis (KOA). Compared to asymptomatic individuals, KOA individuals had lower quadriceps endurance and larger knee joint position errors.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Orthopedics
Ze Gong, Jia Li, Zijun He, Shilin Li, Peihua Cao, Guangfeng Ruan, Yan Zhang, Qing Zeng, Rong Chen, Peng Zheng, Tao Fan, Yijin Zhao, Pengcheng Lu, Zhaohua Zhu, Guozhi Huang
Summary: This study aimed to explore the longitudinal associations between quadriceps strength and knee joint structural abnormalities in knee osteoarthritis (KOA). Results showed that higher quadriceps strength was associated with changes in cartilage damage and BMLs as well as effusion-synovitis in women.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Physiology
Weixin Deng, Ming Lin, Suiqing Yu, Hongying Liang, Zhijie Zhang, Chunzhi Tang, Chunlong Liu
Summary: The study aimed to investigate the effects of hip joint position on quadriceps recruitment pattern of different resistance levels in healthy individuals during knee extension. The results showed that hip joint position significantly influenced the muscle stiffness of the quadriceps, with a positive correlation between muscle stiffness and resistance level.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Neurosciences
Federico Temporiti, Sara Moro, Paola Adamo, Roberto Gatti
Summary: The study investigated the effects of periarticular knee pressure stimuli on quadriceps strength and neuromuscular activity in subjects with knee osteoarthritis. The results showed that periarticular knee pressure stimuli enhanced quadriceps strength and neuromuscular activity in patients with knee osteoarthritis. This approach may represent a new strength training modality for patients with neuromuscular activation deficits for knee osteoarthritis.
JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY
(2023)
Article
Health Care Sciences & Services
Mastour Saeed Alshahrani, Ravi Shankar Reddy, Jaya Shanker Tedla, Faisal Asiri, Adel Alshahrani
Summary: This study found that kinesiophobia is significantly correlated with and predicts pain intensity, joint position sense, and functional performance in individuals with bilateral knee osteoarthritis. Therefore, when planning rehabilitation programs for these patients, the impact of kinesiophobia should be taken into account.
Article
Orthopedics
Qiang Liu, Zhikun Li, Manuela Ferreira, Barton Wise, David J. Hunter, Ke Tao, Jianhao Lin, Yuqing Zhang
Summary: Recent knee injury, more severe radiographic osteoarthritis, and lower quadriceps strength were associated with an increased risk of knee pain exacerbation during walking.
JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY
(2021)
Article
Rheumatology
Diane M. Dickson, Stephanie L. Smith, Gordon J. Hendry
Summary: An advanced ultrasound imaging technique, sonoelastography (SE), was used to evaluate the elasticity of quadriceps and patellar tendons in individuals with knee osteoarthritis (KOA) and asymptomatic older adults (AC). The study found that KOA patients had significantly reduced tendon elasticity compared to asymptomatic controls, and there were associations between SE findings and participant characteristics such as age, BMI, and leg circumference.
RHEUMATOLOGY INTERNATIONAL
(2022)
Article
Rehabilitation
Zongpan LI, Kam L. Leung, Chen Huang, Xiuping Huang, Raymond Chung, Siu N. Fu
Summary: This study aimed to investigate the association between baseline quadriceps passive stiffness and the risk of developing clinical knee osteoarthritis within 12 months. The results showed that higher baseline quadriceps stiffness was associated with a higher risk of developing knee osteoarthritis.
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
(2023)
Article
Sport Sciences
Sebastian Del Rosso, Danilo Pinho Souza, Fabian Munoz, David G. Behm, Carl Foster, Daniel Boullosa
Summary: The study aimed to explain performance and pacing during a 10-km running trial, finding that the inclusion of mechanical and metabolic variables increased the explained variance in performance. Performance and pacing can be explained by combining metabolic and mechanical variables and should be controlled based on performance levels.
JOURNAL OF SPORTS SCIENCES
(2021)
Article
Medicine, General & Internal
Fares Arab, Nishat Quddus, Sohrab A. Khan, Ahmad H. Alghadir, Masood Khan
Summary: This study aimed to investigate the correlation between eccentric quadriceps torque (EQT) and knee pain, physical function, and extension lag in women with knee osteoarthritis (OA). The results showed that EQT had a negative correlation with pain and physical function, and a positive correlation with available ROM.
Article
Multidisciplinary Sciences
Yusuke Suzuki, Hirotaka Iijima, Masatoshi Nakamura, Tomoki Aoyama
Summary: This preliminary study found that individuals with severe knee osteoarthritis (KOA) have significantly lower quadriceps rate of force development (RFD) compared to individuals with early KOA. The decrease in quadriceps RFD is greater than the decrease in maximum quadriceps strength in individuals with severe KOA. This suggests that decreased quadriceps RFD is a modifiable risk factor for progressive KOA.
Article
Engineering, Biomedical
Katsutoshi Nishino, Hiroshi Koga, Yoshio Koga, Masaei Tanaka, Atsushi Nawata, Kazuo Endoh, Masaaki Arakawa, Go Omori
Summary: This study examined the association of quadriceps strength with stride and knee kinematics during gait in adults with normal knee or early knee osteoarthritis. The findings revealed that quadriceps strength was significantly correlated with changes in stride length and knee kinematics during gait in early knee osteoarthritis, suggesting that improving quadriceps strength may help prevent the onset and/or progression of knee osteoarthritis.
CLINICAL BIOMECHANICS
(2021)
Article
Medicine, General & Internal
Mastour Saeed Alshahrani, Ravi Shankar Reddy
Summary: This study evaluates the differences in quadriceps strength and postural stability between individuals with bilateral knee OA and healthy controls, and explores the correlation between quadriceps strength and postural stability in knee OA individuals. Pain was found to mediate the relationship between these physiological factors. The findings emphasize the importance of addressing quadriceps weakness and compromised postural stability.
Article
Biology
Filip Kukic, Vladimir Mrdakovic, Aleksandar Stankovic, Dusko Ilic
Summary: This study investigated the effects of knee joint angle on muscle activation, exerted torque, and whether the knee angle affects the muscle activation-torque ratio. The results showed that knee joint angle had an effect on torque, while muscle activation remained unaffected. Significant effects were not observed in the muscle activation-torque ratio for lateral and medial quadriceps heads. The investigated range of knee joint angles seems to provide optimal conditions for maximal muscle activation but not for torque output, ligament loading, and joint contact forces. Clinicians and sports coaches should carefully consider training goals and choose knee joint angles accordingly.
Article
Engineering, Biomedical
Yamini Krishnan, Yun Jung Yang, Sieun K. Barnes, Han-Hwa K. Hung, Bradley D. Olsen, Paula T. Hammond, Alan J. Grodzinsky
Summary: There are currently no known drugs or treatment methods to prevent post-traumatic osteoarthritis (PTOA), but cationic delivery carriers can help overcome the challenge of drug delivery. In this study, a cationic green fluorescent protein (GFP) was used as a carrier to deliver Insulin-Like Growth Factor 1 (IGF-1) for potential therapeutic treatment of PTOA. Through in vitro experiments and the development of a predictive mathematical transport model, the study provides a foundation for translating these findings into preclinical and potentially clinical applications.
ACTA BIOMATERIALIA
(2022)