Review
Biotechnology & Applied Microbiology
Jinlong Chang, Xuming Sun
Summary: Bioprinting, utilizing 3D printing technology, especially laser-induced forward transfer (LIFT), holds great potential in fabricating intricate biological structures with high precision and enhanced cell viability. LIFT enables the precise transfer of cells or bioinks onto a substrate, making it ideal for producing biomolecular microarrays and various tissues, including skin, blood vessels, and bone. Despite its advantages, there are still challenges that need to be addressed in this field.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Engineering, Biomedical
Mozhgan Keshavarz, Mohammadjavad Jahanshahi, Masoud Hasany, Firoz Babu Kadumudi, Mehdi Mehrali, Mohammad-Ali Shahbazi, Parvin Alizadeh, Gorka Orive, Alireza Dolatshahi-Pirouz
Summary: Significant progress has been made in tissue engineering, but challenges remain. Bioprinting is an innovative technology that can help overcome these challenges. The new trend is 4D bioprinting, which allows printed constructs to change shape and function over time. Alginate, a key material, plays a crucial role in advancing bioprinting.
MATERIALS TODAY BIO
(2023)
Review
Pharmacology & Pharmacy
Annika C. Dell, Grayson Wagner, Jason Own, John P. Geibel
Summary: 3D bioprinting plays a crucial role in tissue engineering in medicine by providing precise and highly customizable methods for creating biological tissues. The selection of appropriate cell ink formulations is vital for process optimization and customization to suit target tissues. Hydrogel-based cell ink formulations show promise for future development in bioprinting technology.
Review
Biotechnology & Applied Microbiology
Earnest P. Chen, Zeren Toksoy, Bruce A. Davis, John P. Geibel
Summary: The aim of tissue engineering with 3D bioprinting is to construct fully functional tissue and organ replacements for clinical applications. One of the main challenges is maintaining tissue viability through the inclusion of complex vascular networks. Recent advancements have made great strides in incorporating vascular networks in 3D printed tissue and organs, offering new possibilities for creating biologically functional tissues and organs.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Engineering, Biomedical
Liliang Ouyang, Jonathan P. Wojciechowski, Jiaqing Tang, Yuzhi Guo, Molly M. Stevens
Summary: This study introduces a method to engineer controlled microporosity in 3D bioprinted hydrogels using microgel-templated porogel (MTP) bioinks. By fabricating templated gelatin microgels with different sizes and mixing them with photo-crosslinkable formulations, the researchers achieved consistent printability and the formation of micropores in situ. This approach provides a facile strategy to compensate for the limited resolution of current bioprinting approaches and engineer precise micropores in 3D printed structures.
ADVANCED HEALTHCARE MATERIALS
(2022)
Review
Chemistry, Applied
Allen Zennifer, Praseetha Senthilvelan, Swaminathan Sethuraman, Dhakshinamoorthy Sundaramurthi
Summary: This review discusses the properties of CMC and its current advances in physical and chemical modifications, as well as its potential applications in tissue engineering. Furthermore, it elaborates on the unique features of CMC in 3D bioprinting applications and highlights future prospects for broader applications in tissue engineering and 3D/4D bioprinting.
CARBOHYDRATE POLYMERS
(2021)
Article
Engineering, Biomedical
Gagan K. Jalandhra, Thomas G. Molley, Tzong-tyng Hung, Iman Roohani, Kristopher A. Kilian
Summary: This study developed a unique printing platform that integrates soft and hard materials concurrently through freeform printing of mineralized constructs within tunable micro-gel suspensions containing living cells. By tuning the microgel stiffness and filler content, chondrogenesis and osteogenesis can be differentially directed within the same construct, enabling the fabrication of osteochondral interfaces in a single step. This versatile one-pot biofabrication approach has the potential to aid in bone disease modeling and tissue engineering.
ACTA BIOMATERIALIA
(2023)
Article
Engineering, Biomedical
Shivaram Selvam, Midhun Ben Thomas, Tuhin Bhowmick, Arun Chandru
Summary: Three-dimensional bioprinting (3DBP) is a promising additive manufacturing technique for fabricating scaffolds that mimic the cues of target tissues. Cell-derived exosomes (EXOs), extracellular vesicles containing diverse cell constituents, have therapeutic potential and can be incorporated and released in a controlled manner using 3DBP. The bioprinting of EXOs holds great promise for tissue engineering and regenerative medicine, allowing the fabrication of complex tissues with native-like microarchitecture and developmental profiles.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Review
Engineering, Biomedical
Changru Zhang, Xiaoqin Qiu, Yu Dai, Weiqing Kong, Yihao Liu, Haoyi Niu, Chengwei Wang, Xuelian Mi, Hui Wang, Ya Ren, Han Yang, Kerong Dai, Jinwu Wang
Summary: Three-dimensional tumor models prepared from patient-derived cells have the potential to imitate the biological development processes of in situ tumors. Bioprinting technologies have improved the simulation of tumor models by enabling the arrangement of cells and materials. Organoid models have been widely appreciated for their ability to maintain high heterogeneity and simulate the developmental process of tumor tissues. The multidisciplinary combination of tumor pathology, molecular biology, material science, and additive manufacturing will promote the development of heterogeneous tumor precision therapies.
BIO-DESIGN AND MANUFACTURING
(2023)
Review
Engineering, Biomedical
Kamil Elkhoury, Margaretha Morsink, Laura Sanchez-Gonzalez, Cyril Kahn, Ali Tamayol, Elmira Arab-Tehrany
Summary: Natural hydrogels are highlighted as promising biomaterials in tissue engineering applications due to their biocompatibility and biodegradability. Innovative biofabrication techniques, such as textile techniques and 3D bioprinting, play a significant role in developing advanced scaffolds for tissue engineering. This review also discusses the emerging applications of biofabricated natural hydrogels in cardiac, neural, and bone tissue engineering.
BIOACTIVE MATERIALS
(2021)
Article
Engineering, Biomedical
Laura Mendoza-Cerezo, Jesus M. Rodriguez-Rego, Antonio Macias-Garcia, Alfonso C. Marcos-Romero, Antonio Diaz-Parralejo
Summary: Bioprinting is a highly useful tool with immense potential in various scientific and biotechnological fields. In medicine, bioprinting focuses on printing cells and tissues for skin regeneration and the production of viable human organs like hearts, kidneys, and bones. This review presents a chronological overview of the significant advancements in bioprinting technique and its current status through an analysis of 122 selected articles out of 31,603 papers found in SCOPUS, Web of Science, and PubMed databases. The paper concludes by discussing the applications and expectations of bioprinting.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Article
Materials Science, Multidisciplinary
Naresh Mahajan, James J. Yoo, Anthony Atala
Summary: Three-dimensional bioprinting technology has experienced rapid development in the field of biofabrication, leading to the successful generation of functional tissues. However, there are still numerous scientific challenges that need to be addressed, requiring the convergence of expertise from multiple disciplines.
Review
Engineering, Biomedical
Nikolas Di Caprio, Jason A. Burdick
Summary: Cellular spheroids are being explored as building blocks for tissue engineering and as tissue models. Biomaterials are being used to guide spheroid formation and function, and also facilitate the fabrication of tissue constructs. This review provides an overview of recent studies on the role of engineered biomaterials in supporting spheroids in biomedical applications.
ACTA BIOMATERIALIA
(2023)
Article
Materials Science, Multidisciplinary
Alperen Abaci, Gulden Camci-Unal, Murat Guvendiren
Summary: Three-dimensional (3D) bioprinting is an emerging technology that can fabricate functional tissues and organs, replicating native tissue function. With its precise positioning of cellular materials and utilization of medical images, 3D bioprinting has enormous potential in biomedical applications, such as tissue engineering and regenerative medicine. It is a rapidly progressing field that has shown clinically relevant uses.
Review
Biochemistry & Molecular Biology
Sven Pantermehl, Steffen Emmert, Aenne Foth, Niels Grabow, Said Alkildani, Rainer Bader, Mike Barbeck, Ole Jung
Summary: The use of additive manufacturing technology in modern medicine is a relatively new field, offering fast and effective ways to produce personalized implants, tissues, and organs for patients. This review provides an overview of various 3D printing technologies, discussing their functions, strengths, and weaknesses in medical applications, as well as summarizing previous studies in tissue engineering.
Article
Materials Science, Multidisciplinary
S. Reyne, G. Duchateau, L. Hallo, J. Y. Natoli, L. Lamaignere
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2015)
Article
Physics, Fluids & Plasmas
W. Cayzac, V. Bagnoud, M. M. Basko, A. Blazevic, A. Frank, D. O. Gericke, L. Hallo, G. Malka, A. Ortner, An. Tauschwitz, J. Vorberger, M. Roth
Article
Multidisciplinary Sciences
D. Hebert, G. Seisson, J. -L. Rullier, I. Bertron, L. Hallo, J. -M. Chevalier, C. Thessieux, F. Guillet, M. Boustie, L. Berthe
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
(2017)
Article
Multidisciplinary Sciences
W. Cayzac, A. Frank, A. Ortner, V. Bagnoud, M. M. Basko, S. Bedacht, C. Blaeser, A. Blazevic, S. Busold, O. Deppert, J. Ding, M. Ehret, P. Fiala, S. Frydrych, D. O. Gericke, L. Hallo, J. Helfrich, D. Jahn, E. Kjartansson, A. Knetsch, D. Kraus, G. Malka, N. W. Neumann, K. Pepitone, D. Pepler, S. Sander, G. Schaumann, T. Schlegel, N. Schroeter, D. Schumacher, M. Seibert, An. Tauschwitz, J. Vorberger, F. Wagner, S. Weih, Y. Zobus, M. Roth
NATURE COMMUNICATIONS
(2017)
Article
Physics, Applied
L. Lavisse, J. -L. Le Garrec, L. Hallo, J. -M. Jouvard, S. Carles, J. Perez, J. B. A. Mitchell, J. Decloux, M. Girault, V. Potin, H. Andrzejewski, M. C. Marco de Lucas, S. Bourgeois
APPLIED PHYSICS LETTERS
(2012)
Article
Chemistry, Physical
L. Hallo, C. Mezel, F. Guillemot, B. Chimier, A. Bourgeade, C. Regan, G. Duchateau, A. Souquet, D. Hebert
APPLIED SURFACE SCIENCE
(2012)
Article
Chemistry, Physical
M. Girault, L. Hallo, L. Lavisse, M. C. Marco de Lucas, D. Hebert, V. Potin, J. -M. Jouvard
APPLIED SURFACE SCIENCE
(2012)
Article
Cell Biology
Amelie Juin, Emmanuelle Planus, Fabien Guillemot, Petra Horakova, Corinne Albiges-Rizo, Elisabeth Genot, Jean Rosenbaum, Violaine Moreau, Frederic Saltel
BIOLOGY OF THE CELL
(2013)
Review
Engineering, Biomedical
Guillaume Luc, Marlene Durand, Denis Collet, Fabien Guillemot, Laurence Bordenave
EXPERT REVIEW OF MEDICAL DEVICES
(2014)
Article
Engineering, Mechanical
G. Seisson, D. Hebert, L. Hallo, J. -M. Chevalier, F. Guillet, L. Berthe, M. Boustie
INTERNATIONAL JOURNAL OF IMPACT ENGINEERING
(2014)
Article
Engineering, Mechanical
G. Seisson, D. Hebert, I. Bertron, J. -M. Chevalier, L. Hallo, E. Lescoute, L. Videau, P. Combis, F. Guillet, M. Boustie, L. Berthe
INTERNATIONAL JOURNAL OF IMPACT ENGINEERING
(2014)
Article
Cell & Tissue Engineering
Sylvain Catros, Fabien Guillemot, Anandkumar Nandakumar, Sophia Ziane, Lorenzo Moroni, Pamela Habibovic, Clemens van Blitterswijk, Benoit Rousseau, Olivier Chassande, Joelle Amedee, Jean-Christophe Fricain
TISSUE ENGINEERING PART C-METHODS
(2012)
Proceedings Paper
Astronomy & Astrophysics
W. Cayzac, A. Frank, A. Ortner, V. Bagnoud, M. M. Basko, S. Bedacht, A. Blazevic, O. Deppert, D. O. Gericke, L. Hallo, A. Knetsch, D. Kraus, G. Malka, K. Pepitone, G. Schaumann, T. Schlegel, D. Schumacher, An Tauschwitz, J. Vorberger, F. Wagner, M. Roth
8TH INTERNATIONAL CONFERENCE ON INERTIAL FUSION SCIENCES AND APPLICATIONS (IFSA 2013)
(2016)
Proceedings Paper
Engineering, Multidisciplinary
D. Hebert, G. Seisson, I. Bertron, L. Hallo, J-M. Chevalier, C. Thessieux, F. Guillet, M. Boustie, L. Berthe
PROCEEDINGS OF THE 2015 HYPERVELOCITY IMPACT SYMPOSIUM (HVIS 2015)
(2015)