Human Cytomegalovirus Encoded Homologs of Cytokines, Chemokines and their Receptors: Roles in Immunomodulation

The 7-transmembrane protein homologue UL78 of the human cytomegalovirus forms oligomers and traffics between the plasma membrane and different intracellular compartments

(2012) Svenja Wagner et al.   ARCHIVES OF VIROLOGY

Human cytomegalovirus-encoded UL33 and UL78 heteromerize with host CCR5 and CXCR4 impairing their HIV coreceptor activity

(2012) K. Tadagaki et al.   BLOOD

Host Immune Responses to a Viral Immune Modulating Protein: Immunogenicity of Viral Interleukin-10 in Rhesus Cytomegalovirus-Infected Rhesus Macaques

(2012) Meghan K. Eberhardt et al.   PLoS One

HCMV-Encoded UL128 Enhances TNF-α and IL-6 Expression and Promotes PBMC Proliferation Through the MAPK/ERK Pathway In Vitro

(2012) Qi Zheng et al.   VIRAL IMMUNOLOGY

Human Cytomegalovirus Clinical Strain-Specific microRNA miR-UL148D Targets the Human Chemokine RANTES during Infection

(2012) Youngkyun Kim et al.   PLoS Pathogens

Heteromerization of human cytomegalovirus encoded chemokine receptors

(2011) Pia Tschische et al.   BIOCHEMICAL PHARMACOLOGY

Human Cytomegalovirus US28 Found in Glioblastoma Promotes an Invasive and Angiogenic Phenotype

(2011) L. Soroceanu et al.   CANCER RESEARCH

PS2-111. Targeting the IL-10 signalling pathway as a vaccine strategy for HCMV

(2011) Mark R. Walter et al.   CYTOKINE

Distribution of UL144, US28 and UL55 genotypes in Polish newborns with congenital cytomegalovirus infections

(2011) E. Paradowska et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Characterization of specific antibodies against cytomegalovirus (CMV)-encoded interleukin 10 produced by 28 % of CMV-seropositive blood donors

(2011) C. de Lemos Rieper et al.   JOURNAL OF GENERAL VIROLOGY

Human Cytomegalovirus pUS27 G Protein-Coupled Receptor Homologue Is Required for Efficient Spread by the Extracellular Route but Not for Direct Cell-to-Cell Spread

(2011) C. M. O'Connor et al.   JOURNAL OF VIROLOGY

Viral Interleukin-10 Expressed by Human Cytomegalovirus during the Latent Phase of Infection Modulates Latently Infected Myeloid Cell Differentiation

(2011) S. Avdic et al.   JOURNAL OF VIROLOGY

Partial Functional Complementation between Human and Mouse Cytomegalovirus Chemokine Receptor Homologues

(2011) H. E. Farrell et al.   JOURNAL OF VIROLOGY

Design and Analysis of Rhesus Cytomegalovirus IL-10 Mutants as a Model for Novel Vaccines against Human Cytomegalovirus

(2011) Naomi J. Logsdon et al.   PLoS One

Human cytomegalovirus latent infection and associated viral gene expression

(2010) Barry Slobedman et al.   Future Microbiology

The Cytomegalovirus UL146 Gene Product vCXCL1 Targets Both CXCR1 and CXCR2 as an Agonist

(2010) Hans R. Lüttichau   JOURNAL OF BIOLOGICAL CHEMISTRY

The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice

(2010) Gerold Bongers et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Cytomegalovirus UL144 Is Associated with Viremia and Infant Development Sequelae in Congenital Infection

(2010) A. Waters et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Sequential mutations associated with adaptation of human cytomegalovirus to growth in cell culture

(2010) D. J. Dargan et al.   JOURNAL OF GENERAL VIROLOGY

Attenuation of innate immunity by cytomegalovirus IL-10 establishes a long-term deficit of adaptive antiviral immunity

(2010) W. L. W. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental human cytomegalovirus latency in CD14+ monocytes

(2010) D. Hargett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human cytomegalovirus tropism for endothelial/epithelial cells: scientific background and clinical implications

(2010) M. Grazia Revello et al.   REVIEWS IN MEDICAL VIROLOGY

HCMV-Encoded Chemokine Receptor US28 Mediates Proliferative Signaling Through the IL-6-STAT3 Axis

(2010) E. Slinger et al.   Science Signaling

The role of cytomegalovirus in angiogenesis

(2010) Patrizia Caposio et al.   VIRUS RESEARCH

Is HCMV a tumor promoter?

(2010) Liliana Soroceanu et al.   VIRUS RESEARCH

The Human Cytomegalovirus-Encoded Chemokine Receptor US28 Promotes Angiogenesis and Tumor Formation via Cyclooxygenase-2

(2009) D. Maussang et al.   CANCER RESEARCH

Identification of TRIM23 as a Cofactor Involved in the Regulation of NF- B by Human Cytomegalovirus

(2009) E. Poole et al.   JOURNAL OF VIROLOGY

The Carboxy-Terminal Tail of Human Cytomegalovirus (HCMV) US28 Regulates both Chemokine-Independent and Chemokine-Dependent Signaling in HCMV-Infected Cells

(2009) M. P. Stropes et al.   JOURNAL OF VIROLOGY

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

Human cytomegalovirus suppresses type I interferon secretion by plasmacytoid dendritic cells through its interleukin 10 homolog

(2009) W.L. William Chang et al.   VIROLOGY

Enhanced monocyte Fc phagocytosis by a homologue of interleukin-10 encoded by human cytomegalovirus

(2009) Anthony Jaworowski et al.   VIROLOGY

Genetic variations in the gB, UL144 and UL149 genes of human cytomegalovirus strains collected from congenitally and postnatally infected Japanese children

(2008) Hainian Yan et al.   ARCHIVES OF VIROLOGY

Immunomodulatory Properties of a Viral Homolog of Human Interleukin-10 Expressed by Human Cytomegalovirus during the Latent Phase of Infection

(2008) C. Jenkins et al.   JOURNAL OF VIROLOGY

NF- B-Mediated Activation of the Chemokine CCL22 by the Product of the Human Cytomegalovirus Gene UL144 Escapes Regulation by Viral IE86

(2008) E. Poole et al.   JOURNAL OF VIROLOGY

Inhibition of CD1 Antigen Presentation by Human Cytomegalovirus

(2008) M. J. Raftery et al.   JOURNAL OF VIROLOGY

Regulation of chemokine activity by posttranslational modification

(2008) A MORTIER et al.   PHARMACOLOGY & THERAPEUTICS

HCMV IL-10 Suppresses Cytokine Expression in Monocytes Through Inhibition of Nuclear Factor-κB

(2008) James Nachtwey et al.   VIRAL IMMUNOLOGY

Polymorphisms within human cytomegalovirus chemokine (UL146/UL147) and cytokine receptor genes (UL144) are not predictive of sequelae in congenitally infected children

(2008) Jinho Heo et al.   VIROLOGY

Stimulation of B lymphocytes by cmvIL-10 but not LAcmvIL-10

(2008) Juliet V. Spencer et al.   VIROLOGY

The role of chemokines in neutrophil biology

(2007) Yoshiro Kobayashi   Frontiers in Bioscience-Landmark

Expression of a human cytomegalovirus latency-associated homolog of interleukin-10 during the productive phase of infection

(2007) Christina Jenkins et al.   VIROLOGY

Identification of novel viral interleukin-10 isoforms of human cytomegalovirus AD169

(2007) Yi-Ling Lin et al.   VIRUS RESEARCH