Review
Chemistry, Multidisciplinary
Ke Li, Craig M. Crews
Summary: PROTACs are a type of molecules with novel event-driven mechanism, offering multiple advantages over traditional inhibitors, such as catalytic nature and targeted protein degradation, which may lead to improved therapeutic outcomes with reduced toxicity. However, further research and development efforts are needed to fully explore their potential.
CHEMICAL SOCIETY REVIEWS
(2022)
Article
Zoology
Gustavo Silva De Miranda, Alessandro P. L. Giupponi, Nikolaj Scharff, Lorenzo Prendini
Summary: This study investigates the phylogeny and biogeography of the pantropical whip spider family Charinidae using morphology and multilocus DNA sequences. Charinidae are monophyletic, with Weygoldtia as the sister group to a monophyletic group comprising Charinus and Sarax. The divergence of Charinus and Sarax coincides with the fragmentation of Pangaea.
ZOOLOGICAL JOURNAL OF THE LINNEAN SOCIETY
(2022)
Review
Environmental Sciences
Lijing Cheng, Karina von Schuckmann, John P. Abraham, Kevin E. Trenberth, Michael E. Mann, Laure Zanna, Matthew H. England, Jan D. Zika, John T. Fasullo, Yongqiang Yu, Yuying Pan, Jiang Zhu, Emily R. News, Ben Bronselaer, Xiaopei Lin
Summary: This Review synthesizes estimates of past and future ocean heat content (OHC) changes using observations and models. The top 2,000 m of the global ocean has significantly warmed since the 1950s, with the rate of warming increasing over the decades. The observed warming is largest in the Atlantic Ocean and southern oceans, and the projected future warming will have extensive impacts on marine ecosystems and society.
NATURE REVIEWS EARTH & ENVIRONMENT
(2022)
Review
Materials Science, Multidisciplinary
Joseph Rich, Zhenhua Tian, Tony Jun Huang
Summary: The research in intracellular delivery technologies has surged with the advancement in cell-based therapies and reprogramming. Physical cell membrane permeabilization techniques, especially sonoporation, show promise in delivering functional cargos to various cells, but bubble-based methods may have limitations such as requiring contrast agents and potential damage to cell components. Development of non-bubble-based sonoporation mechanisms aims to overcome these limitations and improve intracellular delivery efficiency.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Anthropology
R. Lee Lyman
Summary: Archaeological typology has been traditionally seen as descriptive, but it is important for it to be descriptive in terms of relevant attributes to be analytically useful. Recent discussions have raised concerns about how formal variation can be masked by the categorization process, echoing the idea of the tyranny of typologies. There has been a lack of in-depth discussions on the hows and whys of archaeological systematics, potentially leading to reduced consideration and application of typologies in the discipline.
JOURNAL OF ARCHAEOLOGICAL SCIENCE
(2021)
Review
Chemistry, Multidisciplinary
Wentao Jiang, Ziyu Wu, Zheng Gao, Mimi Wan, Min Zhou, Chun Mao, Jian Shen
Summary: Artificial cells are constructed to imitate natural cells and can be used for studying biological processes and the origin of life. They can be endowed with various functions through the incorporation of proteins and genes, and have great potential in therapeutic applications.
Review
Chemistry, Medicinal
Yasuhiro Nishida, Pernilla Christina Berg, Behnaz Shakersain, Karen Hecht, Akiko Takikawa, Ruohan Tao, Yumeka Kakuta, Chiasa Uragami, Hideki Hashimoto, Norihiko Misawa, Takashi Maoka
Summary: This review article provides a comprehensive exploration of the history, chemical and physical attributes, distribution, and biosynthesis of astaxanthin (AX). It also delves into the health benefits, biofunctional characteristics, and market status of AX, aiming to provide a robust foundation for future scientific endeavors addressing societal needs for sustainable nutritional and medicinal solutions.
Review
Plant Sciences
Ian Max Moller, Allan G. Rasmusson, Olivier Van Aken
Summary: The study of plant mitochondria began in the 1950s, focusing on establishing basic properties and unique characteristics compared to mammalian mitochondria. With advancements in molecular biology and genomics, further unique features were discovered, including the large size of plant mtDNA, unique mRNA maturation process, and a large proteome with many unique proteins.
Review
Chemistry, Multidisciplinary
Xiaozhou Ma, Jelco Albertsma, Dieke Gabriels, Rens Horst, Sevgi Polat, Casper Snoeks, Freek Kapteijn, Huseyin Burak Eral, David A. A. Vermaas, Bastian Mei, Sissi de Beer, Monique Ann van der Veen
Summary: Large amounts of carbon monoxide are produced through industrial processes, but separating carbon monoxide from other gases is challenging due to their similar physical properties. However, carbon monoxide is valuable in the production of chemicals and hydrocarbons, making the development of efficient CO separation processes important for both industry and the environment.
CHEMICAL SOCIETY REVIEWS
(2023)
Review
Chemistry, Multidisciplinary
Xinxin Wu, Zhigang Ma, Tingting Feng, Chen Zhu
Summary: Rearrangement reactions are crucial in organic chemistry, improving synthetic efficiency and molecular complexity. Ionic rearrangement reactions and radical-mediated rearrangements are the focus of research, with new radical rearrangements revealing migratory behavior of functional groups.
CHEMICAL SOCIETY REVIEWS
(2021)
Review
Chemistry, Multidisciplinary
Yungyeong Lee, Cyrille Boyer, Min Sang Kwon
Summary: In this review, the history, progress, and applications of photocontrolled reversible addition-fragmentation chain transfer (RAFT) polymerization are briefly summarized. The challenges of this technique, including photoinduced electron/energy transfer-RAFT (PET-RAFT), photoiniferter, and photomediated cationic RAFT polymerization, are discussed. Visible-light-driven RAFT polymerization has gained significant attention due to its low energy consumption and safe reaction procedure, and the use of visible-light photocatalysis offers additional benefits such as spatiotemporal control and oxygen tolerance. However, a comprehensive understanding of the reaction mechanism is still lacking. Recent efforts combining quantum chemical calculations and experimental evidence have been made to elucidate the polymerization mechanisms. This review provides insights for the better design of polymerization systems and explores the full potential of photocontrolled RAFT polymerization in both academic and industrial applications.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Neurosciences
Marcela Lipovsek, Cedric Bardy, Cathryn R. Cadwell, Kristen Hadley, Dmitry Kobak, Shreejoy J. Tripathy
Summary: Patch-seq is a revolutionary technique in neuroscience that integrates morphology, physiology, and gene expression data to study neuronal biology comprehensively. It enables targeted study of specific neuronal populations, compilation of multimodal cell type atlases, and investigation of the molecular basis of morphologic and functional diversity. This technique has the potential for further technical development and implementation in various research areas to directly link gene expression to brain function.
JOURNAL OF NEUROSCIENCE
(2021)
Review
Physics, Particles & Fields
Nathaniel Craig
Summary: This article assesses the state of naturalness in high-energy physics and summarizes recent approaches to the three major naturalness problems: the cosmological constant problem, the electroweak hierarchy problem, and the strong CP problem.
EUROPEAN PHYSICAL JOURNAL C
(2023)
Review
Chemistry, Multidisciplinary
Ludan Yue, Xueyang Zhang, Chenchen Zhao, Rongchang Chen, Xiaoyuan Chen, Lang Rao
Summary: Inhaled drug delivery is an emerging route for the treatment of lung diseases, with advantages over oral and intravenous routes. However, there are physiological barriers that affect delivery efficacy in the respiratory tract. This review provides an overview of inhaled drug delivery methods, highlighting non-invasive strategies for treating lung diseases.
Review
Endocrinology & Metabolism
Michael A. Morris, Babak Saboury, Mark Ahlman, Ashkan A. Malayeri, Elizabeth C. Jones, Clara C. Chen, Corina Millo
Summary: The goal of parathyroid imaging is to identify the sources of excessive parathyroid hormone secretion before surgery. Various imaging approaches, including ultrasound, 4DCT, 4DMRI, and scintigraphy with 99mTc-Sestamibi, have been used for this purpose. Combining structural imaging with molecular imaging in hybrid approaches, such as PET/CT and PET/MRI, can provide robust information on both structure and function.
FRONTIERS IN ENDOCRINOLOGY
(2022)
