期刊
YONSEI MEDICAL JOURNAL
卷 52, 期 1, 页码 196-198出版社
YONSEI UNIV COLL MEDICINE
DOI: 10.3349/ymj.2011.52.1.196
关键词
Bortezomib; multiple myeloma; adverse effect; atrioventricular block
Bortezomib is an inhibitor of 26S proteasome, which is an effective treatment for multiple myeloma. The common adverse effects of bortezomib are asthenic conditions, gastrointestinal disturbances, and peripheral neuropathy. Here we describe a patient with dyspnea and general weakness because of complete atrioventricular block while receiving bortezomib. We immediately stopped bortezomib, and after inserting a permanent VDD pacemaker, the patients' symptoms disappeared.
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