期刊
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
卷 131, 期 10, 页码 1453-1460出版社
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/yakushi.131.1453
关键词
environmental chemistry; atom economy; 1,3-transposition of hydroxyl group; combined catalyst system; lipase; transition metal
This review article describes our recent efforts to develop environmentally benign transformations of allyl and propargyl alcohols via the 1,3-transposition of their hydroxyl groups using combined catalyst systems. This methodology allows for successful transformation under mild conditions, which has never been achieved using each catalyst. Representative examples of this methodology include the following three reactions. First, the combination of oxovanadium compounds and lipases resulted in the dynamic kinetic resolution of racemic allyl alcohols to give optically active allyl esters in high yields. Second, Mo-Au-Ag combination catalysis dramatically accelerated the rearrangement of diverse propargyl alcohols into a,alpha,beta-unsaturated carbonyl compounds. Finally, the choice of suitable heteropoly acids for the rearrangement of propargyl alcohols led to the selective preparation of both (Z)- and (E)-enones.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据