Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes viain vivoandin vitrooxidation of midazolam and triazolam

Influence of Dietary Substances on Intestinal Drug Metabolism and Transport

(2011) Christina S. Won et al.   CURRENT DRUG METABOLISM

Tissue Distribution and Gender-Divergent Expression of 78 Cytochrome P450 mRNAs in Mice

(2011) Helen J. Renaud et al.   TOXICOLOGICAL SCIENCES

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Comparative gene expression of intestinal metabolizing enzymes

(2009) Ho-Chul Shin et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Inhibition and Stimulation of Intestinal and Hepatic CYP3A Activity: Studies in Humanized CYP3A4 Transgenic Mice Using Triazolam

(2009) R. A. B. van Waterschoot et al.   DRUG METABOLISM AND DISPOSITION

Tissue-Specific mRNA Expression Profiles of Human Solute Carrier 35 Transporters

(2009) Masuhiro Nishimura et al.   Drug Metabolism and Pharmacokinetics

Separate evaluation of intestinal and hepatic metabolism of three benzodiazepines in rats with cannulated portal and jugular veins: comparison with the profile in non-cannulated mice

(2009) J. Kuze et al.   XENOBIOTICA

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

(2008) Ulrich M. Zanger et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Comparison of Inducibility of Multidrug Resistance (MDR)1, Multidrug Resistance-Associated Protein (MRP)1, and MRP2 mRNAs by Prototypical Microsomal Enzyme Inducers in Primary Cultures of Human and Cynomolgus Monkey Hepatocytes

(2008) Masuhiro Nishimura et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The biological and clinical role of drug transporters at the intestinal barrier

(2008) Roos L. Oostendorp et al.   CANCER TREATMENT REVIEWS

Tissue-specific mRNA Expression Profiles of Human Solute Carrier Transporter Superfamilies

(2008) Masuhiro Nishimura et al.   Drug Metabolism and Pharmacokinetics