Article
Nutrition & Dietetics
Jonas Buren, Madelene Ericsson, Nagila Raquel Teixeira Damasceno, Anna Sjodin
Summary: The study found that a ketogenic low-carbohydrate high-fat diet led to adverse lipid profiles in healthy, young, normal-weight women, including increased LDL cholesterol and other related markers.
Article
Nutrition & Dietetics
Jennifer A. Fleming, Penny M. Kris-Etherton, Kristina S. Petersen, David J. Baer
Summary: Incorporating lean beef into a Mediterranean-style diet does not attenuate the reduction in lipid and lipoprotein concentrations as compared to an average American diet.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Fisheries
Victor H. Marques, Renata G. Moreira, Giovana S. Branco, Renato M. Honji, Artur N. Rombenso, Maria Teresa Viana, Paulo H. de Mello, Jose A. Mata-Sotres, Bruno C. Araujo
Summary: The study found that alternative lipid sources rich in saturated and monounsaturated fatty acids can be used in cobia aquafeeds when supplemented with long-chain polyunsaturated fatty acids without impairing production performance. High levels of saturated fatty acids were disproportionally deposited in the liver and muscle, while monounsaturated fatty acids were mainly deposited in the liver and muscle.
Article
Nutrition & Dietetics
Angela C. Bersch-Ferreira, Wendy L. Hall, Renato H. N. Santos, Camila R. Torreglosa, Geni Sampaio, Jacqueline Tereza da Silva, Renata Alves, Maria Beatriz Ross, Marcella Omena Gehringer, Cristiane Kovacs, Aline Marcadenti, Daniel Magnoni, Bernardete Weber, Marcelo Macedo Rogero
Summary: The study evaluated the effect of the Brazilian Cardioprotective Diet Program on cardiovascular disease secondary prevention patients, showing a significant reduction in BMI and waist circumference in the BALANCE Program group after six months of follow-up. Plasma alpha-linolenic acid levels increased, but there was no impact on plasma inflammatory biomarkers.
CLINICAL NUTRITION
(2021)
Review
Biology
Carlo Maria Barbagallo, Angelo Baldassare Cefalu, Antonina Giammanco, Davide Noto, Rosalia Caldarella, Marcello Ciaccio, Maurizio Rocco Averna, Emilio Nardi
Summary: Chronic kidney disease is an important risk factor for cardiovascular disease, with dyslipidemia often present in patients with CKD. Various lipoprotein abnormalities occur due to impaired enzymes pathways and proteins involved in lipoprotein metabolism in CKD patients. Hypolipidemic treatments may alter the progression of CVD in CKD patients.
Article
Biochemistry & Molecular Biology
Anna E. Engell, Henrik L. Jorgensen, Bent S. Lind, Anton Pottegard, Christen L. Andersen, John S. Andersen, Margit Kriegbaum, Mia K. Grand, Lise Bathum
Summary: Lipid levels in blood have decreased significantly in the general population due to the use of statins. This trend was observed in primary health care patients who were not using statins from 2001 to 2018, with substantial decreases in total cholesterol and low-density lipoprotein cholesterol levels, especially in the elderly population.
LIPIDS IN HEALTH AND DISEASE
(2021)
Article
Nutrition & Dietetics
Juliane Menzel, Alessa Longree, Klaus Abraham, Matthias B. Schulze, Cornelia Weikert
Summary: The vegan diet has gained popularity in Germany in recent years. A study comparing vegans and omnivores found that vegans have a lower intake of total fat, saturated fatty acids, and monounsaturated fatty acids, but higher intake of total polyunsaturated fatty acids, omega-3, and omega-6 fatty acids. Additionally, vegans have more favorable plasma fatty acid profiles, with lower proportions of saturated fatty acids, trans fatty acids, and omega-3 fatty acids, but higher proportions of omega-6 fatty acids. Overall, a vegan diet is associated with a more favorable dietary fat intake and plasma fatty acid profile, which may reduce cardiovascular risk.
Article
Clinical Neurology
Jose Jimenez-Torres, Juan F. Alcala-Diaz, Jose D. Torres-Pena, Francisco M. Gutierrez-Mariscal, Ana Leon-Acuna, Purificacion Gomez-Luna, Carolina Fernandez-Gandara, Gracia M. Quintana-Navarro, Jose C. Fernandez-Garcia, Pablo Perez-Martinez, Jose M. Ordovas, Javier Delgado-Lista, Elena M. Yubero-Serrano, Jose Lopez-Miranda
Summary: The study compared the effects of a Mediterranean diet and a low-fat diet on cardiovascular disease prevention, finding that the Mediterranean diet could reduce the progression of atherosclerosis, as shown by decreased IMT-CC and carotid plaque height.
Article
Biochemistry & Molecular Biology
Liv Nesse Hande, Christian Kjellmo, Kristin Pettersen, Stefan Ljunggren, Helen Karlsson, Karin Cederbrant, Maritha Marcusson-Stahl, Anders Hovland, Knut Tore Lappegard
Summary: High-dose n-3 PUFAs supplements reduce atherogenic lipoproteins in FH subjects without affecting HDL-C function.
Article
Biochemistry & Molecular Biology
Suresh K. Nagumalli, Rose A. Willett, Aline de Conti, Volodymyr P. Tryndyak, Mark I. Avigan, Goncalo Gamboa da Costa, Frederick A. Beland, Ivan Rusyn, Igor P. Pogribny
Summary: Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease characterized by excessive accumulation of lipids in hepatocytes. Recent studies have shown that changes in lipid composition, particularly in PUFA/MUFA ratios, play a crucial role in the development and severity of NAFLD. This research analyzed the fatty acid composition in various mouse models and demonstrated that alterations in PUFA/MUFA ratios can serve as a diagnostic marker for NAFLD severity.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Hyungjong Park, Yoonkyung Chang, Heajung Lee, Iksun Hong, Tae-Jin Song
Summary: The study investigates the association between total cholesterol (TC) variability and the occurrence of venous thromboembolism (VTE) using a Korean database. The results show a positive correlation between higher TC variability and the occurrence of VTE, emphasizing the importance of maintaining stable TC levels to prevent VTE.
Review
Medicine, General & Internal
Reed Mszar, Sarah Bart, Alexander Sakers, Daniel Soffer, Dean G. Karalis
Summary: Hypertriglyceridemia (HTG) is a common medical condition in patients with cardiometabolic risk factors and can increase the risk of atherosclerotic cardiovascular disease (ASCVD) if ignored. Current guidelines recommend clinical evaluation and lifestyle-based interventions to address potential causes of elevated triglyceride (TG) levels. Statin therapy, alone or in combination with other lipid-lowering medications, is recommended for individuals with mild to moderate HTG at risk of ASCVD. Novel therapies targeting apoC-III and ANGPTL3 have shown promise in reducing TG levels. Public health strategies are needed to improve access to effective pharmacotherapies, affordable and nutritious food options, and timely healthcare services.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Maureen Sampson, Rami A. Ballout, Daniel Soffer, Anna Wolska, Sierra Wilson, Jeff Meeusen, Leslie J. Donato, Erica Fatica, James D. Otvos, Eliot A. Brinton, Robert S. Rosenson, Peter Wilson, Marcelo Amar, Robert Shamburek, Sotirios K. Karathanasis, Alan T. Remaley
Summary: This study developed a new algorithm for classifying lipoprotein disorders based on the standard lipid panel, categorizing patients into classical Fredrickson-like phenotypes and introducing a new hypolipidemic phenotype (Type VI) due to genetic mutations in apoB-metabolism. The validity of the new algorithm was confirmed through lipid analysis by NMR and by concordance with classification by agarose gel electrophoresis/beta-quantification, demonstrating its potential for improving the care of patients at risk for ASCVD.
LIPIDS IN HEALTH AND DISEASE
(2021)
Article
Nutrition & Dietetics
Teresa Padro, Anallely Lopez-Yerena, Antonio Perez, Gemma Vilahur, Lina Badimon
Summary: High-density lipoproteins (HDLs) are complex particles that have multiple cardiovascular protective properties. Diet, specifically supplementation with ?3 and phytosterols, has been shown to improve the lipid profile of HDL. This study found that ?3 supplementation had greater effects on HDL lipidome compared to phytosterols, particularly in cholesteryl esters (CEs). Furthermore, the HDL lipidome was found to be sex-dependent. Overall, this study highlights the importance of diet and sex in modulating the HDL lipid profile.
Article
Cardiac & Cardiovascular Systems
Bethan L. Clifford, Kelsey E. Jarrett, Joan Cheng, Angela Cheng, Marcus Seldin, Pauline Morand, Richard Lee, Mary Chen, Angel Baldan, Thomas Q. de Aguiar Vallim, Elizabeth J. Tarling
Summary: This study reveals a novel role of RNF130 in regulating LDL-C levels by modulating the availability of LDLR.
CIRCULATION RESEARCH
(2023)
Article
Endocrinology & Metabolism
Aesha Shah, William C. Dodson, Penny M. Kris-Etherton, Allen R. Kunselman, Christy M. Stetter, Carol L. Gnatuk, Stephanie J. Estes, Kelly C. Allison, David B. Sarwer, Patrick M. Sluss, Christos Coutifaris, Anuja Dokras, Richard S. Legro
Summary: Oral contraceptive pills have a significant impact on the hormones of patients with polycystic ovary syndrome, but this does not correlate with live birth.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Review
Environmental Sciences
Lauren C. Mead, Alison M. Hill, Sharayah Carter, Alison M. Coates
Summary: Research indicates that nut consumption can improve children's diet quality, but the effects on cardiometabolic and gastrointestinal health are inconsistent. Further studies are needed to explore the broader health benefits of nuts in children, with consideration of higher doses and longer intervention periods.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Nutrition & Dietetics
Jennifer A. Fleming, Penny M. Kris-Etherton, Kristina S. Petersen, David J. Baer
Summary: Incorporating lean beef into a Mediterranean-style diet does not attenuate the reduction in lipid and lipoprotein concentrations as compared to an average American diet.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Susan J. Ward, Alison M. Hill, Jonathan D. Buckley, Siobhan Banks, Varinderpal S. Dhillon, Stacey L. Holman, Janna L. Morrison, Alison M. Coates
Summary: The study aimed to investigate the relationship between diet quality and telomere length in Australian adults after a 12-week dietary intervention with an almond-enriched diet. Results showed that although diet quality improved with the almond-enriched diet, it did not significantly affect telomere length. Future studies should explore the impact of more substantial dietary changes over longer periods of time.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Nutrition & Dietetics
Muzi Na, Yanxiu Wang, Xinyuan Zhang, Christopher Sarpong, Penny M. Kris-Etherton, Ming Gao, Aijun Xing, Shouling Wu, Xiang Gao
Summary: The DASH dietary pattern is associated with lower nighttime blood pressure variability in elderly adults, independent of sleep parameters and other factors.
JOURNAL OF NUTRITION
(2022)
Article
Nutrition & Dietetics
Sharayah Carter, Alison M. Hill, Jonathan D. Buckley, Sze-Yen Tan, Geraint B. Rogers, Alison M. Coates
Summary: This study compared postprandial changes in appetite-regulating hormones and self-reported appetite ratings after consuming almonds or a carbohydrate-rich snack bar. The results showed that almonds had better responses in postprandial C-peptide, glucose-dependent insulinotropic polypeptide, and glucagon compared to the snack bar, but there were no differences in self-reported appetite ratings and energy intake after a buffet meal challenge.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Obstetrics & Gynecology
Tricia L. Hart, Kristina S. Petersen, Penny M. Kris-Etherton
Summary: A healthy eating pattern is crucial for optimal pregnancy outcomes and successful lactation. The preconception period is a critical time during which good nutrition benefits both the mother and the offspring. The presence of overweight and obesity, combined with poor nutrition, poses risks to maternal and infant health.
FERTILITY AND STERILITY
(2022)
Review
Peripheral Vascular Disease
Penny M. Kris-Etherton, Philip A. Sapp, Terrance M. Riley, Kristin M. Davis, Tricia Hart, Olivia Lawler
Summary: The recent rise in cardiovascular disease deaths in the USA has led to interest in identifying and implementing effective strategies to reverse this trend. Healthy lifestyle behaviors are crucial for CVD prevention, and even small changes can lower the risk. However, unhealthy behaviors may attenuate the effects of changing other lifestyle behaviors.
CURRENT ATHEROSCLEROSIS REPORTS
(2022)
Letter
Cardiac & Cardiovascular Systems
Kamil F. Faridi, Penny M. Kris-Etherton, Karen E. Aspry
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Sport Sciences
Chloe J. Otte, Evangeline Mantzioris, Brianna S. Salagaras, Alison M. Hill
Summary: This prospective observational study aims to evaluate seasonal changes in dietary intake and health parameters of professional AFLW athletes. The results showed that AFLW athletes did not meet energy and carbohydrate requirements across the preseason and competition seasons, which may impact health and performance.
SCIENCE AND MEDICINE IN FOOTBALL
(2023)
Review
Peripheral Vascular Disease
Sharayah Carter, Elizabeth S. Connole, Alison M. Hill, Jonathan D. Buckley, Alison M. Coates
Summary: This review summarizes recent evidence on the association between egg consumption and risk of cardiovascular disease (CVD) mortality, CVD incidence, and CVD risk factors. The evidence from observational studies is mixed, with some reporting an increased risk of CVD mortality with highest egg consumption, while others find no association. The relationship between egg intake and total CVD incidence is also inconsistent, with reports of increased risk, decreased risk, or no association. Most studies suggest a reduced risk or no association between egg consumption and CVD risk factors. Ethnicity may influence the risk of CVD with egg consumption, likely due to variations in dietary habits.
CURRENT ATHEROSCLEROSIS REPORTS
(2023)
Review
Nutrition & Dietetics
Tricia L. Hart, Kristina S. Petersen, Penny M. Kris-Etherton
Summary: This study conducted a systematic review of the effects of cottonseed oil on lipid metabolism and found that cottonseed oil can improve lipid/lipoprotein levels compared with olive oil. The predictive equations suggest that cottonseed oil can be incorporated into a healthy dietary pattern without significantly affecting lipids/lipoproteins.
Article
Endocrinology & Metabolism
Sharayah Carter, Alison M. Hill, Lauren C. Mead, Hoi Y. Wong, Catherine Yandell, Jonathan D. Buckley, Sze-Yen Tan, Geraint B. Rogers, Francois Fraysse, Alison M. Coates
Summary: This study evaluated the effects of an energy-restricted diet containing almonds compared to a diet containing carbohydrate-rich snacks on weight and cardiometabolic outcomes. The results showed that both diets led to improvements in weight and cardiometabolic health, with the almond-enriched diet showing greater improvements in some lipoprotein subfractions.
Review
Nutrition & Dietetics
Diane Mendoza-Sarmiento, Emmanuele V. Mistades, Alison M. Hill
Summary: This review examined the effect of polyphenol-containing pigmented rice on cardiometabolic risk factors in adults. The results showed that acute intake of pigmented rice increased plasma antioxidant activity and lowered postprandial glucose and insulin levels, while chronic consumption was associated with reductions in fasting glucose, weight, and diastolic blood pressure. However, more high-quality trials are needed to further investigate these findings due to the limited number of studies and differences in study design.
CURRENT NUTRITION REPORTS
(2023)
Article
Nutrition & Dietetics
Valerie K. Sullivan, Kristina S. Petersen, Victor L. Fulgoni, Fulya Eren, Martha E. Cassens, Michael T. Bunczek, Penny M. Kris-Etherton
Summary: This study found that higher quality diets are primarily distinguished by the types of fats and grain-based foods consumed, with whole fruits, seafood, and plant proteins being most favorably associated with cardiometabolic risk factors.
CURRENT DEVELOPMENTS IN NUTRITION
(2021)