Article
Clinical Neurology
Holly Elser, Michelle Caunca, David H. Rehkopf, Wells Andres, Rebecca F. Gottesman, Scott E. Kasner, Kristine Yaffe, Andrea L. C. Schneider
Summary: The study found that the diagnosis and treatment rates of poststroke depression have been increasing among stroke patients over the years. Women have a higher diagnosis rate compared to men, while racial/ethnic minorities have a lower diagnosis rate. Furthermore, women and older patients are more likely to receive treatment.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Clinical Neurology
Xiao-Min Tan, Zi-Xuan Liao, Ying-Ying Zhao, Xiao-Cui Sun, Fa-Ling Yi
Summary: This study examined the impact of longitudinal changes in depressive symptoms in middle-aged adults before and after their first stroke, as well as the influence of different ages. The results showed that middle-aged populations have a higher risk of depressive symptoms after a first stroke compared to older populations, and there is an increased severity of depressive symptoms in the two years before and after stroke.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Rehabilitation
Janina Kaarre, Tamar Abzhandadze, Katharina S. Sunnerhagen
Summary: Impaired cognition early after stroke could not predict self-reported feeling of depression 3 months post-stroke. Female patients had twice the odds of self-reported feeling of depression compared with male patients.
JOURNAL OF REHABILITATION MEDICINE
(2021)
Article
Endocrinology & Metabolism
Chan Soon Park, Eue-Keun Choi, Kyung-Do Han, Juhwan Yoo, Hyo-Jeong Ahn, Soonil Kwon, So-Ryoung Lee, Seil Oh, Gregory Y. H. Lip
Summary: This study investigated the association between changes in regular physical activity and the risk of developing atrial fibrillation (AF) in patients with type 2 diabetes mellitus (T2DM), as well as the optimal range of physical activity based on energy expenditure. The results showed that starting and maintaining regular physical activity were both associated with a lower risk of incident AF. Based on energy expenditure, new exercisers who engaged in regular physical activity for at least 1,500 MET-min/week and exercise maintainers who engaged in at least 1,000 MET-min/week had a lower risk of developing AF compared to non-exercisers.
Article
Clinical Neurology
Moamina Ismail, Vincent C. T. Mok, Adrian Wong, Lisa Au, Brian Yiu, Zhaolu Wang, Winnie C. W. Chu, Anne Y. Y. Chan, Florence S. Y. Fan, Sze H. Ma, Vincent Ip, Bonaventure Ip, Karen Ma, Howan Leung, Yannie O. Y. Soo, Thomas W. H. Leung, Ho Ko, Alexander Y. L. Lau, Bonnie Y. K. Lam
Summary: The presence of >= 3 lacunes, history of ischemic heart disease, history of ischemic stroke, and a lower baseline MoCA score are associated with delayed-onset dementia after stroke/transient ischemic attack, while APOEe4 allele, medial temporal lobe atrophy, and recurrent stroke were not predictive of delayed-onset dementia.
INTERNATIONAL JOURNAL OF STROKE
(2022)
Article
Medicine, General & Internal
Lisa M. Jamieson, Gail Garvey, Joanne Hedges, Cathy Leane, Isaac Hill, Alex Brown, Xiangqun Ju, Sneha Sethi, David Roder, Richard M. Logan, Newell Johnson, Megan Smith, Annika Antonsson, Karen Canfell
Summary: This study aims to estimate the prevalence of oral HPV infection among Indigenous Australians, identify risk factors associated with OPSCC-related HPV types, develop HPV-related health state valuations, and determine the cost-effectiveness of extending publicly-funded HPV vaccination. Findings indicate a high prevalence of oral HPV infection, with lower prevalence of HPV types associated with OPSCC. Future plans include continued follow-up of the cohort with comprehensive clinical examinations and blood tests for early stage OPSCC.
Article
Cardiac & Cardiovascular Systems
Jiqing Li, Zhentang Zhang, Shucheng Si, Fuzhong Xue
Summary: This study longitudinally evaluated the impact of leisure-time physical activity (LTPA) on cardiovascular disease (CVD) risk in hypertensive patients, showing a negative association between LTPA and CVD risk, with a breakpoint of 417 minutes per week for LTPA.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Medicine, General & Internal
Samuel Hall, Jacqueline Birks, Ian Anderson, Andrew Bacon, Paul M. Brennan, David Bennett, Emmanuel Chavredakis, Giles Critchley, Graham Dow, Jonathan Downer, James Galea, Patrick Grover, Nihal Gurusinghe, Adel Helmy, Gueorgui Kounin, Nitin Mukerji, Hiren Patel, Jash Patel, Nicholas Ross, Jerome St George, Mario Teo, Christos Michael Tolias, Nikolaos Tzerakis, Christopher Uff, Janneke van Beijum, Kristin Veighey, Edward White, Peter Whitfield, Diederik Oliver Bulters, ROAR Investigators
Summary: This study aims to test the accuracy of PHASES in a UK population, evaluate additional predictors of aneurysm rupture, and assess long-term UIA rupture rates. It is a longitudinal multicentre study that will collect baseline demographics and aneurysm characteristics of patients with known UIA in neurosurgery units. The results will be disseminated through peer-reviewed journals.
Article
Clinical Neurology
Ozra Barooj-Kiakalaee, Seyed-Hamzeh Hosseini, Reza-Ali Mohammadpour-Tahmtan, Monirolsadate Hosseini-Tabaghdehi, Shayesteh Jahanfar, Zahra Esmaeili-Douki, Zohreh Shahhosseini
Summary: This study aimed to explore the relationship between paternal postpartum depression and maternal prenatal and postpartum depression, as well as marital satisfaction. The results showed that maternal prenatal and postpartum depression, as well as paternal prenatal depression, were associated with paternal postpartum depression. Additionally, marital satisfaction had a direct and indirect relationship with paternal postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Medicine, General & Internal
Ping-Han Tsai, Chang-Fu Kuo, Lai-Chu See, Pei-Ru Li, Jung-Sheng Chen, Wen-Yi Tseng
Summary: This study estimates the risk of stroke in Taiwanese patients with gout. The results show that gout patients have a higher risk of ischemic and hemorrhagic stroke after 3 years.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Vivek Nambiar, Manu Raj, Damodaran Vasudevan, Renjitha Bhaskaran, Remya Sudevan
Summary: The study reported low 1-year all-cause mortality among stroke patients, with predictors including age, baseline NIHSS score, and baseline mRS score.
Article
Neurosciences
Durgesh Chaudhary, Isabel Friedenberg, Vishakha Sharma, Pragyan Sharma, Vida Abedi, Ramin Zand, Jiang Li
Summary: This study aimed to investigate the incidence of depression in stroke patients and factors associated with post-stroke depression. Findings showed that women, patients with a history of prior stroke or myocardial infarction, and those with Medicaid insurance were more likely to develop post-stroke depression.
Article
Environmental Sciences
Whanhee Lee, Xiao Wu, Seulkee Heo, Joyce Mary Kim, Kelvin C. Fong, Ji-Young Son, Matthew Benjamin Sabath, Ana Trisovic, Danielle Braun, Jae Yoon Park, Yong Chul Kim, Jung Pyo Lee, Joel Schwartz, Ho Kim, Francesca Dominici, Ziyad Al-Aly, Michelle L. Bell
Summary: Recent studies suggest a link between air pollution exposure and reduced kidney function, but its association with acute kidney injury (AKI) remains unclear. In this population-based study, long-term exposure to PM2.5, NO2, and O3 was found to be associated with an increased risk of first hospital admission for AKI. The associations were observed even at lower levels of air pollution.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2023)
Article
Psychiatry
Iman Alaie, Richard Ssegonja, Anna Philipson, Anne-Liis von Knorring, Margareta Moller, Lars von Knorring, Mia Ramklint, Hannes Bohman, Inna Feldman, Lars Hagberg, Ulf Jonsson
Summary: The study found that adolescent depression is associated with higher social transfer payments, especially for those with persistent depression and comorbid psychiatric disorders. This suggests that the clinical heterogeneity of early-life depression needs to be considered from a longer-term societal perspective.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2021)
Article
Peripheral Vascular Disease
Jean-Michel Halimi, Jean-Baptiste de Freminville, Philippe Gatault, Arnaud Bisson, Benedicte Sautenet, Valentin Maisons, Pascal Vigny, Denis Angoulvant, Laurent Fauchier
Summary: This study investigated the characteristics and prognosis of hypertensive encephalopathy (HE) and found that HE had a poor prognosis with high risks of death and other complications. Hypertension and concomitant stroke significantly influenced the prognosis of HE.
Article
Biotechnology & Applied Microbiology
Marco Heppe Montero, Ruth Gil-Prieto, Stefan Walter, Fernando Aleixandre Blanquer, Angel Gil De Miguel
Summary: Bronchiolitis is a significant burden in children under 2 years of age in Spain, with over 100,000 hospitalizations and 82 deaths reported from 2012 to 2017. Most cases requiring hospitalization were in infants under 3 months of age, and the annual average cost to the National Health Care System was euro58 million.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2022)
Article
Geriatrics & Gerontology
David Gomez-Cabrero, Stefan Walter, Imad Abugessaisa, Rebeca Minambres-Herraiz, Lucia Bernad Palomares, Lee Butcher, Jorge D. Erusalimsky, Francisco Jose Garcia-Garcia, Jose Carnicero, Timothy C. Hardman, Harald Mischak, Petra Zuerbig, Matthias Hackl, Johannes Grillari, Edoardo Fiorillo, Francesco Cucca, Matteo Cesari, Isabelle Carrie, Marco Colpo, Stefania Bandinelli, Catherine Feart, Karine Peres, Jean-Francois Dartigues, Catherine Helmer, Jose Vina, Gloria Olaso, Irene Garcia-Palmero, Jorge Garcia Martinez, Pidder Jansen-Duerr, Tilman Grune, Daniela Weber, Giuseppe Lippi, Chiara Bonaguri, Alan J. Sinclair, Jesper Tegner, Leocadio Rodriguez-Manas
Summary: The study identified various biomarkers associated with frailty, including protective markers like vitamin D3 and lutein zeaxanthin, as well as the risk marker cardiac troponin T. The relationship patterns of these biomarkers differ depending on the presence or absence of disability.
Article
Public, Environmental & Occupational Health
Willa D. Brenowitz, Scott C. Zimmerman, Teresa J. Filshtein, Kristine Yaffe, Stefan Walter, Thomas J. Hoffmann, Eric Jorgenson, Rachel A. Whitmer, M. Maria Glymour
Summary: This study used Mendelian randomization to estimate that the impact of Alzheimer's disease on body mass index occurs in middle age, leading to weight loss. The divergence in BMI between high-risk and low-risk groups begins after the age of 47.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
Editorial Material
Public, Environmental & Occupational Health
J. Robin Moon, Amanda Falick Ascher
AMERICAN JOURNAL OF PUBLIC HEALTH
(2021)
Review
Health Care Sciences & Services
Jessica R. Marden, Claudio Santos, Brian Pfister, Richard Able, Henry Lane, Michael Somma, Jing Zhao, James Signorovitch, Julie Parsons, Susan Apkon
Summary: The aim of the study was to describe reasons for switching from prednisone/prednisolone to deflazacort and associated clinical outcomes among patients with DMD and BMD in the USA. The primary reasons for switching were to slow disease progression and tolerability, with 90-95% of patients finding deflazacort effective in addressing these reasons.
JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH
(2021)
Article
Psychiatry
Else Foverskov, Justin S. White, Marie Norredam, Trine Froslev, Min Hee Kim, M. Maria Glymour, Lars Pedersen, Henrik T. Sorensen, Rita Hamad
Summary: This study based on refugees in Denmark found that resettling in socioeconomically disadvantaged neighborhoods increased the risk of psychiatric disorders among refugees. The results suggest that targeted placement of newly arrived refugees could help improve their mental health.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Sarah E. Gollust, Kathleen T. Call, J. Robin Moon, Bonnie Cluxton, Zinzi Bailey
Summary: This paper describes the curriculum of the Robert Wood Johnson Foundation Interdisciplinary Research Leaders (IRL) program, which aims to cultivate leaders, promote health equity in communities, and address health inequities through research and action.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Geriatrics & Gerontology
Jason R. Smith, Laura E. Gibbons, Paul K. Crane, Dan M. Mungas, M. Maria Glymour, Jennifer J. Manly, Laura B. Zahodne, Elizabeth Rose Mayeda, Richard N. Jones, Alden L. Gross
Summary: Telephone-administered cognitive assessments are an cost-effective alternative to face-to-face assessments, but there are mode effects in cognitive measurement, particularly in memory and attention tests, for older adults. The importance of these mode differences depends on the research question and sample.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2023)
Article
Psychology, Clinical
Ellicott C. Matthay, Meghan L. Smith, M. Maria Glymour, Justin S. White, Jaimie L. Gradus
Summary: This article introduces the conceptual foundations, implementation, and strengths and limitations of instrumental variables (IVs) in research. IV methods offer an alternative approach to controlling for confounders without the need for their correct identification, measurement, and control. They are particularly relevant for assessing the causal effects of stress and trauma on outcomes.
PSYCHOLOGICAL TRAUMA-THEORY RESEARCH PRACTICE AND POLICY
(2023)
Letter
Clinical Neurology
Sarah F. Ackley, M. Maria Glymour
ALZHEIMERS & DEMENTIA
(2023)
Article
Public, Environmental & Occupational Health
Crystal Shaw, Yingyan Wu, Scott C. Zimmerman, Eleanor Hayes-Larson, Thomas R. Belin, Melinda C. Power, M. Maria Glymour, Elizabeth Rose Mayeda
Summary: Incomplete longitudinal data is a common issue in life-course epidemiology, and multiple imputation (MI) is often used to handle missing data. However, there is limited research on the performance and feasibility of MI methods in real-data settings. This study compared three MI methods using real data and found that predictive mean matching may be a favorable strategy for imputing life-course exposure data due to its consistently low root mean square error, competitive computation times, and few implementation challenges.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Health Care Sciences & Services
Craig M. McDonald, Jessica R. Marden, Perry B. Shieh, Brenda L. Wong, Henry Lane, Adina Zhang, Ha Nguyen, Molly Frean, Panayiota Trifillis, Karyn Koladicz, James Signorovitch
Summary: This study found that daily deflazacort had greater benefits than daily prednisone, particularly among older patients with more advanced disease progression.
JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH
(2023)
Article
Clinical Neurology
Sarah F. Ackley, Jingxuan Wang, Ruijia Chen, Melinda C. Power, Isabel Elaine Allen, M. Maria Glymour
Summary: A Bayesian approach was used to analyze the results of several trials on amyloid-targeting drugs, indicating a small benefit of amyloid reduction on cognition.
ALZHEIMERS & DEMENTIA
(2023)
Article
Neurosciences
Priscilla A. Amofa-Ho, Ariana M. Stickel, Ruijia Chen, Lindsay C. Kobayashi, M. Maria Glymour, Chloe W. Eng
Summary: This study investigated the relationship between early-life education and later-life cognitive function, and examined the mediating roles of Alzheimer's and neurovascular biomarkers. The results showed that commonly measured neurobiomarkers only partially mediated the relationships between education and multidomain cognitive function.
JOURNAL OF ALZHEIMERS DISEASE
(2023)
Article
Agronomy
J. Robin Moon, Craig Willingham, Shqipe Gjevukaj, Nicholas Freudenberg
Summary: The article connects the COVID-19 pandemic in New York City with food insecurity and diet-related diseases, exploring the intersection of these three issues. It suggests that adopting syndemic theory can strengthen the synergies between community-driven solutions and municipal government responses, reducing the health burden in the Bronx.
JOURNAL OF AGRICULTURE FOOD SYSTEMS AND COMMUNITY DEVELOPMENT
(2021)