Article
Oncology
Claire H. Pernar, Giovanni Parmigiani, Edward L. Giovannucci, Eric B. Rimm, Svitlana Tyekucheva, Massimo Loda, Stephen P. Finn, Matthew G. Vander Heiden, Michelangelo Fiorentino, Ericka M. Ebot, Lorelei A. Mucci
Summary: The study suggests that high-intensity physical activity may influence gene expression in prostate tissue, particularly in adjacent normal tissue where cancer- and immune-related pathways are enriched. Although no significant gene sets were identified in tumor tissue, potential effects on TGF beta, apoptosis, and p53 signaling pathways were observed.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Geriatrics & Gerontology
Mark Kheifets, Abigail Goshen, Uri Goldbourt, Guy Witberg, Alon Eisen, Ran Kornowski, Yariv Gerber
Summary: This study examined the impact of education, income, and neighborhood socioeconomic status on physical activity and frailty in older adults. The study found that multiple socioeconomic status measures were positively associated with physical activity, which was a strong predictor of lower subsequent frailty risk.
Article
Oncology
Justin C. C. Brown, Chao Ma, Qian Shi, Charles S. S. Fuchs, Jeffrey Meyer, Donna Niedzwiecki, Tyler Zemla, Felix Couture, Philip Kuebler, Pankaj Kumar, DeQuincy Lewis, Benjamin Tan, Smitha Krishnamurthi, Eileen M. M. O'Reilly, Anthony F. F. Shields, Jeffrey A. A. Meyerhardt
Summary: The purpose of this study was to determine the specific types, durations, and intensities of recreational physical activity that are associated with the greatest improvements in disease-free survival (DFS) for patients with colon cancer. The study found that engaging in larger volumes of recreational physical activity, longer durations of light-to-moderate-intensity aerobic exercise, or any vigorous-intensity aerobic exercise were significantly associated with improved DFS.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Review
Oncology
Barbara Bressi, Maribel Cagliari, Massimiliano Contesini, Elisa Mazzini, Franco Antonio Mario Bergamaschi, Alfredo Moscato, Maria Chiara Bassi, Stefania Costi
Summary: The study found a lack of evidence supporting the effectiveness of physical exercise in preventing bone mineral density loss and the risk of accidental falls and fractures in men with prostate cancer receiving androgen deprivation therapy. However, clinical guidelines recommend physical exercise as part of the clinical management due to its known health benefits.
SUPPORTIVE CARE IN CANCER
(2021)
Review
Oncology
Christopher T. V. Swain, Ann E. Drummond, Roger L. Milne, Dallas R. English, Kristy A. Brown, Makayla W. C. Lou, Leonessa Boing, Amy Bageley, Tina L. Skinner, Eline H. van Roekel, Melissa M. Moore, Tom R. Gaunt, Richard M. Martin, Sarah J. Lewis, Brigid M. Lynch
Summary: The protective effect of physical activity on breast cancer incidence may be partly mediated by inflammation. Meta-analyses of intervention studies showed that exercise interventions reduced levels of circulating inflammatory biomarkers, providing support for the biological plausibility of the physical activity-inflammation-breast cancer pathway.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Health Care Sciences & Services
Daniela Lucini, Mara Malacarne, Wolfgang Gatzemeier, Eleonora Pagani, Giuseppina Bernardelli, Gianfranco Parati, Massimo Pagani
Summary: The increased cardiometabolic risk in breast cancer survivors is attributed to multiple mechanisms, including hormonal and immunological dysfunction as well as cardiac autonomic regulation. This study found that physical activity can improve cardiac autonomic regulation, metabolism, and psychological well-being in breast cancer survivors.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Geriatrics & Gerontology
Pablo Martinez-Amezcua, Emmanuel Garcia Morales, Kelley P. Gabriel, Erin E. Dooley, Bjoern Hornikel, Josef Coresh, Frank R. Lin, James S. Pankow, A. Richey Sharrett, Jennifer A. Schrack, Kevin J. Sullivan, Nicholas Reed, Jennifer A. Deal, Priya Palta
Summary: This study examines the association between midlife leisure-time physical activity and hearing loss in older ages. Results show that meeting physical activity recommendations during midlife is associated with better hearing and reduced risk of hearing loss in older ages.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Sport Sciences
Jonathan G. Stine, Michelle T. Long, Kathleen E. Corey, Robert E. Sallis, Alina M. Allen, Matthew J. Armstrong, David E. Conroy, Daniel J. Cuthbertson, Andres Duarte-Rojo, Kate Hallsworth, Ingrid J. Hickman, Matthew R. Kappus, Shelley E. Keating, Christopher J. A. Pugh, Yaron Rotman, Tracey L. Simon, Eduardo Vilar-Gomez, Vincent Wai-sun Wong, Kathryn H. Schmitz
Summary: Although most individuals with nonalcoholic fatty liver disease are inactive and do not achieve recommended amounts of physical activity (PA), regular PA has been shown to have various benefits. These benefits include a reduction in liver fat, improvement in body composition, cardiovascular fitness, vascular biology, and health-related quality of life. This roundtable document discusses the benefits of PA and provides recommendations for PA assessment, counseling, and prescription, as well as when to refer to an exercise specialist.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Geriatrics & Gerontology
Zhaoli Liu, Jing Wang
Summary: This study examined the relationship between the perceived importance of exercise in cancer prevention and physical activity as well as sedentary behavior in older adults. The findings showed that older adults who acknowledged the protective role of exercise in cancer prevention were more likely to engage in physical activity and less likely to have sedentary behavior.
Article
Public, Environmental & Occupational Health
Cliff Lindeman, Richard Golonka, Doug Klein, Michael K. Stickland, John C. Spence
Summary: This study compared the characteristics of patients with and without physical activity documented in primary care electronic medical records using pan-Canadian data. The results showed that physical activity was rarely documented in the records, with male patients, younger age groups, no comorbidities, higher blood pressure risk categories, better socioeconomic status, and normal body mass index having the most mentions of physical activity. Female physicians and those practicing in academic sites were more likely to document physical activity. Logistic regression analysis identified several significant covariates, including patient and physician age, comorbidities, and the use of electronic medical record systems.
PREVENTIVE MEDICINE
(2023)
Article
Multidisciplinary Sciences
Fakir M. Amirul Islam, Mohammad Ariful Islam, Mohammad Arzan Hosen, Elisabeth A. Lambert, Ralph Maddison, Gavin W. Lambert, Bruce R. Thompson
Summary: Engaging in high physical activity and having a positive attitude towards physical activity are associated with lower blood pressure levels in rural Bangladesh. Awareness programs should be implemented to promote the benefits of physical activity and increase participation in high physical activity.
Article
Multidisciplinary Sciences
Isabelle Dore, Audrey Plante, Nathalie Bedrossian, Sarah Montminy, Kadia St-Onge, Jany St-Cyr, Marie-Pascale Pomey, Danielle Charpentier, Lise Pettigrew, Isabelle Brisson, Fred Saad, Francois Tournoux, Marie-France Raynault, Anne-Marie Mes-Masson, Lise Gauvin
Summary: This project aims to develop a practice guideline for physical activity promotion for cancer patients in clinical and community settings. By synthesizing knowledge, analyzing data, collecting and analyzing experiences from patients and healthcare providers, we hope to successfully integrate physical activity into cancer treatment and survivorship to improve the physical and mental health of patients.
Article
Oncology
Suzanne Dufresne, Cindy Richard, Arthur Dieumegard, Luz Orfila, Gregory Delpon, Sophie Chiavassa, Brice Martin, Laurent Rouviere, Jean-Michel Escoffre, Edward Oujagir, Baudouin Denis de Senneville, Ayache Bouakaz, Nathalie Rioux-Leclercq, Vincent Potiron, Amelie Rebillard
Summary: Physical activity is being increasingly integrated into cancer patient care to improve survival outcomes, but its specific impact on radiotherapy efficiency remains unclear. Different modalities of physical activity have varying effects on tumor growth, suggesting that the anti-cancer benefits may depend on the type of exercise.
Article
Oncology
Paulina S. Marell, Robert A. Vierkant, Janet E. Olson, Joerg Herrmann, Nicole Larson, Nathan K. LeBrasseur, Stacy D. D'Andre, Andrea L. Cheville, Toure Barksdale, Charles L. Loprinzi, Fergus Couch, Kathryn J. Ruddy
Summary: This study identifies characteristics associated with an increased likelihood of meeting physical activity guidelines among breast cancer survivors, including younger age, longer time after diagnosis, absence of recurrence, absence of metastatic disease, absence of bilateral mastectomy, and lower BMI.
Article
Oncology
Erica Schleicher, Edward McAuley, Kerry S. Courneya, Phillip Anton, Diane K. Ehlers, Siobhan M. Phillips, Robert A. Oster, Dorothy Pekmezi, Laura Q. Rogers
Summary: This study investigated moderators of response to a physical activity behavior change intervention for breast cancer survivors. The results showed that breast cancer survivors who received chemotherapy, were within 2 years of diagnosis, and were single were less likely to achieve moderate-to-vigorous physical activity of 150+ weekly minutes. Further research is needed to determine additional support and resources that may benefit these subgroups of breast cancer survivors.
SUPPORTIVE CARE IN CANCER
(2023)