Review
Oncology
Omar Fahmy, Maxim Kochergin, Anastasios D. Asimakopoulos, Georgios Gakis
Summary: Extended pelvic lymph node dissection has been a standard practice during radical cystectomy for patients with muscle invasive bladder cancer. However, based on recent studies, standard pelvic lymph node dissection up to the level of iliac bifurcation is sufficient and there is no additional oncologic benefit from extending the dissection above this level.
SEMINARS IN ONCOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Liang-Liang Hu, Zhong-Qiang Guo, Peng Dai, Gang Chen, Tao Tian
Summary: Pheochromocytomas are rare neuroendocrine tumors that produce catecholamines. Bladder involvement is uncommon, and common symptoms include hypertension, headache, hematuria, and syncope. While transurethral resection may be performed in some patients, most require partial or radical cystectomy.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Oncology
Andrew T. Lenis, Katherine E. Fero, Leslie Ojeaburu, Patrick M. Lec, Vishnukamal Golla, Wayne Brisbane, Michael S. Leapman, Karim Chamie
Summary: The study found that partial cystectomy is less common among patients with muscle-invasive bladder cancer and is associated with lower utilization of neoadjuvant chemotherapy and lymph node dissection but fewer treatment delays. The adequacy of lymph node dissection is associated with improved overall survival.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2021)
Article
Urology & Nephrology
Alberto Martini, Luca Afferi, Stefania Zamboni, Julianne G. Schultz, Chiara Lonati, Agostino Mattei, R. Jeffrey Karnes, Matteo Soligo, Armando Stabile, Ettore Di Trapani, Ottavio De Cobelli, Giuseppe Simone, Claudio Simeone, Mario Alvarez-Maestro, Giorgio Gandaglia, Andrea Gallina, Renzo Colombo, Alberto Briganti, Francesco Montorsi, Evanguelos Xylinas, Shahrokh F. Shariat, Marco Moschini
Summary: The study found that patients with variant histology bladder cancer have a higher risk of recurrence, requiring extended surveillance time, and different histological types have different risks of recurrence and metastasis.
JOURNAL OF UROLOGY
(2021)
Article
Urology & Nephrology
Riccardo Mastroianni, Mariaconsiglia Ferriero, Gabriele Tuderti, Umberto Anceschi, Alfredo Maria Bove, Aldo Brassetti, Leonardo Misuraca, Ashanti Zampa, Giulia Torregiani, Edoardo Ghiani, Diana Giannarelli, Salvatore Guaglianone, Michele Gallucci, Giuseppe Simone
Summary: This study compared perioperative and 6-month outcomes between open radical cystectomy (ORC) and robot-assisted radical cystectomy (RARC) with totally intracorporeal urinary diversion (UD). Results showed that RARC with intracorporeal UD had a significantly lower overall perioperative transfusion rate compared to ORC. However, perioperative complications, hospital stay, and 6-month health-related quality of life were similar between the two groups. Long-term follow-up is needed to assess oncologic and functional outcomes.
JOURNAL OF UROLOGY
(2022)
Review
Surgery
Rahul Jena, Nikita Shrivastava, Aditya Prakash Sharma, Gautam Ram Choudhary, Aneesh Srivastava
Summary: Pelvic lymph node dissection is essential for radical cystectomy in muscle invasive bladder cancer, but there is controversy surrounding what constitutes an adequate dissection. Different anatomical templates and surrogate markers have been proposed, with conflicting evidence on their efficacy. Standardized nomenclature and further research are needed to determine the optimal approach.
FRONTIERS IN SURGERY
(2021)
Article
Oncology
Eunhye Yi, Yang-Sook Yoo, Sunhee Lee, Hanjong Park
Summary: This study aims to understand the experiences of illness among bladder cancer patients in Korea after radical cystectomy. Through interviews, six themes were derived, representing the emotional state and adaptation process after surgery.
Review
Medicine, General & Internal
Pau Sarrio-Sanz, Laura Martinez-Cayuelas, Blanca Lumberas, Laura Sanchez-Caballero, Antonio Palazon-Bru, Vicente F. Gil-Guillen, Luis Gomez-Perez
Summary: This study aimed to identify risk-predictive models for bladder-specific cancer mortality in patients undergoing radical cystectomy and assess their clinical utility and risk of bias. The findings showed that clinical predictors can be used to assess the risk of bladder-specific cancer mortality, but the studies had a high risk of bias and their applicability is uncertain.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2022)
Article
Oncology
Aleksander Slusarczyk, Piotr Zapala, Tomasz Piecha, Lukasz Zapala, Tomasz Borkowski, Piotr Radziszewski
Summary: The study found that patients who underwent radical nephroureterectomy for upper urinary tract urothelial cancer after radical cystectomy experienced poor overall survival and cancer-specific survival, with most surgeries being performed for locally advanced tumors. Independent risk factors for worse survival included UTUC T stage, presence of metastasis, and male gender.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Urology & Nephrology
Ahmed S. Elsayed, Sean Gibson, Zhe Jing, Carl Wijburg, Andrew A. Wagner, Alexandre Mottrie, Prokar Dasgupta, James Peabody, Ahmed A. Hussein, Khurshid A. Guru
Summary: This study reported and analyzed disease relapse following robot-assisted radical cystectomy using a multinational database, finding a 25% relapse rate among patients and various patterns of relapse. The multivariate regression models identified that node positive status and higher disease stage (pT3 or greater) were significantly associated with relapse and survival rates.
JOURNAL OF UROLOGY
(2021)
Article
Urology & Nephrology
Abhinav Khanna, Tanner Miest, Vidit Sharma, Rebecca Campbell, Patrick Hensley, Prabin Thapa, Andrew Zganjar, Matthew K. Tollefson, R. Houston Thompson, Igor Frank, R. J. Karnes, Prithvi B. Murthy, Georges P. Haber, Neema Navai, Ashish M. Kamat, Colin Dinney, Byron Lee, Stephen A. Boorjian
Summary: This study aimed to assess the association between the extent of lymph node dissection (LND) during radical cystectomy (RC) for nonmuscle-invasive bladder cancer (NMIBC) and survival outcomes. The results showed that a greater extent of LND was associated with improved local pelvic recurrence-free survival (LPRS), cancer-specific survival (CSS), and overall survival (OS). This suggests that the inclusion of LND in the treatment of NMIBC can enhance patient prognosis.
JOURNAL OF UROLOGY
(2022)
Article
Medicine, General & Internal
Artur Leminski, Krystian Kaczmarek, Wojciech Michalski, Bartosz Malkiewicz, Katarzyna Kotfis, Marcin Slojewski
Summary: Radical cystectomy with pelvic lymph node dissection is the main treatment for muscle-invasive bladder cancer, with the number of removed lymph nodes significantly influencing survival outcomes. The benefits of adequate lymph node removal were reduced in patients who received neoadjuvant chemotherapy, suggesting the need for further research to validate these findings.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Oncology
Na Yin, Wei Zhao, Tao He, Tingchao Li, Xu Lei, Hao He, Zongmin Long, Yan Wang
Summary: This case reports a rare case of squamous cell carcinoma of the bladder in a 65-year-old female patient. The use of partial cystectomy combined with left ureteral reimplantation resulted in no disease recurrence or metastasis after 10 years. Retrospective analysis of the treatment plan and admission provides valuable reference significance for the management of SCC of the bladder.
FRONTIERS IN ONCOLOGY
(2023)
Article
Urology & Nephrology
Francesco Soria, Peter C. Black, Adrian S. Fairey, Michael S. Cookson, Evan Y. Yu, Wassim Kassouf, Marc A. Dall'Era, Srikala S. Sridhar, John S. McGrath, Jonathan L. Wright, Andrew C. Thorpe, Todd M. Morgan, Siamak Daneshmand, Jeff M. Holzbeierlein, Trinity J. Bivalacqua, Scott North, Daniel A. Barocas, Yair Lotan, Petros Grivas, Andrew J. Stephenson, Jay B. Shah, Bas W. van Rhijn, Philippe E. Spiess, Shahrokh F. Shariat, Paolo Gontero
Summary: In patients with cT2N0 bladder cancer and no preoperative hydronephrosis, neoadjuvant chemotherapy (NAC) increased the rate of pathological complete response and downstaging, showing a positive impact on overall survival.
Article
Oncology
Elke Rammant, Ann Van Hecke, Karel Decaestecker, Maarten Albersen, Steven Joniau, Wouter Everaerts, Femke Jansen, Nihal E. Mohamed, Roos Colman, Mieke Van Hemelrijck, Valerie Fonteyne
Summary: The majority of bladder cancer patients undergoing radical cystectomy have moderate to high supportive care needs, but few utilize or are willing to use supportive care services, with many patients preferring to talk to their physician.
Article
Public, Environmental & Occupational Health
Aynslie M. Hinds, Songul Bozat-Emre, Paul Van Caeseele, Salaheddin M. Mahmud
Editorial Material
Surgery
Katerina Neumann, Salaheddin M. Mahmud, Andrew McKay, Jason Park, Jennifer Metcalfe, David J. Hochman
CANADIAN JOURNAL OF SURGERY
(2015)
Article
Hematology
Kristjan Paulson, Anna Serebrin, Pascal Lambert, Julie Bergeron, Janeve Everett, Andrea Kew, David Jones, Salah Mahmud, Catherine Meloche, Mitchell Sabloff, Ismail Sharif, John Storring, Donna Turner, Matthew D. Seftel
BRITISH JOURNAL OF HAEMATOLOGY
(2014)
Article
Immunology
Erin Schillberg, Michael Isaac, Xianding Deng, Gisele Peirano, John L. Wylie, Paul Van Caeseele, Dylan R. Pillai, Hasantha Sinnock, Salaheddin M. Mahmud
CLINICAL INFECTIOUS DISEASES
(2014)
Article
Public, Environmental & Occupational Health
L. H. Thompson, M. T. Malik, A. Gumel, T. Strome, S. M. Mahmud
EPIDEMIOLOGY AND INFECTION
(2014)
Article
Infectious Diseases
D. M. Skowronski, C. Chambers, S. Sabaiduc, G. De Serres, J. A. Dickinson, A. L. Winter, K. Fonseca, J. B. Gubbay, H. Charest, M. Petric, M. Krajden, S. M. Mahmud, P. Van Caeseele, T. L. Kwindt, A. Eshaghi, N. Bastien, Y. Li
Article
Geriatrics & Gerontology
Songul Bozat-Emre, Malcolm Doupe, Anita L. Kozyrskyj, Ruby Grymonpre, Salaheddin M. Mahmud
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
(2015)
Article
Oncology
Salaheddin M. Mahmud, Erich V. Kliewer, Pascal Lambert, Songul Bozat-Emre, Alain A. Demers
JOURNAL OF CLINICAL ONCOLOGY
(2014)
Article
Immunology
Danuta M. Skowronski, Naveed Z. Janjua, Suzana Sabaiduc, Gaston De Serres, Anne-Luise Winter, Jonathan B. Gubbay, James A. Dickinson, Kevin Fonseca, Hugues Charest, Nathalie Bastien, Yan Li, Trijntje L. Kwindt, Salaheddin M. Mahmud, Paul Van Caeseele, Mel Krajden, Martin Petric
JOURNAL OF INFECTIOUS DISEASES
(2014)
Article
Multidisciplinary Sciences
Danuta M. Skowronski, Naveed Z. Janjua, Gaston De Serres, Suzana Sabaiduc, Alireza Eshaghi, James A. Dickinson, Kevin Fonseca, Anne-Luise Winter, Jonathan B. Gubbay, Mel Krajden, Martin Petric, Hugues Charest, Nathalie Bastien, Trijntje L. Kwindt, Salaheddin M. Mahmud, Paul Van Caeseele, Yan Li
Article
Gastroenterology & Hepatology
Mahmoud Torabi, Christopher Green, Zoann Nugent, Salaheddin M. Mahmud, Alain A. Demers, Jane Griffith, Harminder Singh
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2014)
Article
Urology & Nephrology
Tamer A. Abouelgreed, Mohamed A. Abdelaal, Moamen M. Amin, Adel Elatreisy, Osama Shalkamy, Abdrabuh M. Abdrabuh, Osama M. Ghoneimy, Hamdy Aboutaleb
Summary: This study evaluated and compared the outcomes of ECIRS in the treatment of partial staghorn renal calculi in prone split-leg positions versus GMSV positions. The results showed that there were no significant differences in technical aspects, success rate, operative time, complications, safety, and effectiveness between the two approaches.
Article
Urology & Nephrology
Hamdy A. Aboutaleb, Tamer A. Abouelgreed, Moamen M. Amin, Mohamed F. Sultan
Summary: A comparative study of ECSR and ICSR techniques for treating VUR in complete duplex systems showed similar success rates and postoperative complications, with ECSR having fewer complications and shorter hospital stay. ECSR is preferred for open surgical repair, while ICSR should be reserved for complicated cases requiring reconstructive surgery.
Article
Urology & Nephrology
Tamer A. Ali, Mohamed A. Abdelaal, Moamen M. Amin, Mohamed K. Saif-Elnasr
Summary: This study found no statistically significant difference in outcome, complications, or PCA use between delivering 60 and 120 shocks per minute during SWL for the treatment of solitary renal stones using a Dornier Compact Delta II lithotripter with a mean stone area of 62 mm(2).
JOURNAL OF CLINICAL UROLOGY
(2021)
Article
Urology & Nephrology
Hamdy Aboutaleb, Tamer A. Ali, Ahmed Zaghloul, Moamen M. Amin
JOURNAL OF CLINICAL UROLOGY
(2018)