Article
Urology & Nephrology
Carl J. Wijburg, Charlotte T. J. Michels, Gerjon Hannink, Janneke P. C. Grutters, Maroeska M. Rovers, J. Alfred Witjes
Summary: This study did not find significant differences in complications and health-related quality of life between robot-assisted radical cystectomy and open radical cystectomy. However, there were some differences in secondary outcomes, with the main limitation being residual confounding.
Review
Oncology
Chengyu You, Qingchao Li, Yongjin Yang, Liangliang Qing, Shuai Liu, Yanan Wang, Zhilong Dong
Summary: This study compared the perioperative and oncologic outcomes of extraperitoneal radical cystectomy (EPRC) and transperitoneal radical cystectomy (TPRC). The results showed that although EPRC had a higher incidence of lymphoceles, it had similar oncologic outcomes and fewer early complications, particularly in terms of postoperative gastrointestinal complications and ileus.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Woodson W. Smelser, Joseph Hogan Randall, Joshua Caldwell, Katherine Glavin, Eugene K. Lee, Ajay Nangia, Jeffrey M. Holzbeierlein
Summary: The study found that changes in androgen levels were prevalent in male patients undergoing radical cystectomy, with some patients experiencing low testosterone levels at certain postoperative stages. Despite significant weight loss after surgery, no significant changes in psoas muscle cross-sectional area were observed.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2021)
Article
Surgery
Xiaofang Zhang, Chaoyi Deng, Qianyi Wan, Rui Zhao, Liping Han, Xiao Wang
Summary: This study investigated the relationship between sarcopenia and postoperative pulmonary complications (PPCs) after gastric cancer surgery. The results showed that sarcopenia is an independent risk factor for PPCs. However, the study only provided correlation and not causation.
FRONTIERS IN SURGERY
(2023)
Article
Oncology
Stefano Tappero, Andrea Panunzio, Lukas Hohenhorst, Cristina Cano Garcia, Francesco Barletta, Mattia Piccinelli, Zhe Tian, Stefano Parodi, Alessandro Antonelli, Markus Graefen, Felix K. H. Chun, Alberto Briganti, Ottavio De Cobelli, Fred Saad, Shahrokh F. Shariat, Nazareno Suardi, Marco Borghesi, Carlo Terrone, Pierre I. Karakiewicz
Summary: The effect of radical cystectomy (RC) on cancer-specific mortality (CSM) is uncertain in non-metastatic sarcomatoid bladder cancer (SBC) patients. This study aimed to evaluate the benefit of RC in SBC patients and compare it with urothelial bladder cancer (UCB).
Article
Urology & Nephrology
Anke Richters, Theodora M. Ripping, Lambertus A. Kiemeney, Anna M. Leliveld, Bas W. G. van Rhijn, Jorg R. Oddens, R. Jeroen A. van Moorselaar, Catharina A. Goossens-Laan, Richard P. Meijer, Joost L. Boormans, J. Alfred Witjes, Katja K. H. Aben
Summary: This study aimed to evaluate the association between hospital volume and postoperative mortality for patients undergoing radical cystectomies. The findings suggest that increasing the annual RC volume criteria to beyond 30 cases could further decrease postoperative mortality.
Article
Urology & Nephrology
Reza Nabavizadeh, Rodrigo Rodrigues Pessoa, Mihai G. Dumbrava, Vignesh T. Packiam, Prabin Thapa, Robert Tarrell, Matthew K. Tollefson, R. Jeffrey Karnes, Igor Frank, Abhinav Khanna, Paras Shah, Vidit Sharma, Stephen A. Boorjian
Summary: This study reports on peri-operative outcomes of bladder cancer patients undergoing radical cystectomy with cutaneous ureterostomy urinary diversion. The results suggest that the use of cutaneous ureterostomy is associated with faster surgery and postoperative recovery, but it is also associated with a higher rate of postoperative ureteral obstruction.
Article
Urology & Nephrology
Francesco Soria, Peter C. Black, Adrian S. Fairey, Michael S. Cookson, Evan Y. Yu, Wassim Kassouf, Marc A. Dall'Era, Srikala S. Sridhar, John S. McGrath, Jonathan L. Wright, Andrew C. Thorpe, Todd M. Morgan, Siamak Daneshmand, Jeff M. Holzbeierlein, Trinity J. Bivalacqua, Scott North, Daniel A. Barocas, Yair Lotan, Petros Grivas, Andrew J. Stephenson, Jay B. Shah, Bas W. van Rhijn, Philippe E. Spiess, Shahrokh F. Shariat, Paolo Gontero
Summary: In patients with cT2N0 bladder cancer and no preoperative hydronephrosis, neoadjuvant chemotherapy (NAC) increased the rate of pathological complete response and downstaging, showing a positive impact on overall survival.
Article
Urology & Nephrology
Alberto Martini, Luca Afferi, Stefania Zamboni, Julianne G. Schultz, Chiara Lonati, Agostino Mattei, R. Jeffrey Karnes, Matteo Soligo, Armando Stabile, Ettore Di Trapani, Ottavio De Cobelli, Giuseppe Simone, Claudio Simeone, Mario Alvarez-Maestro, Giorgio Gandaglia, Andrea Gallina, Renzo Colombo, Alberto Briganti, Francesco Montorsi, Evanguelos Xylinas, Shahrokh F. Shariat, Marco Moschini
Summary: The study found that patients with variant histology bladder cancer have a higher risk of recurrence, requiring extended surveillance time, and different histological types have different risks of recurrence and metastasis.
JOURNAL OF UROLOGY
(2021)
Article
Oncology
Felix Merboth, Heiner Nebelung, Natalie Wotschel, Hendrik Liebscher, Franziska Eckert, Janusz von Renesse, Jasmin Hasanovic, Thilo Welsch, Johannes Fritzmann, Daniel E. Stange, Verena Plodeck, Ralf-Thorsten Hoffmann, Marius Distler, Juergen Weitz, Johanna Kirchberg
Summary: This study found that robot-assisted minimally invasive esophagectomy (RAMIE) is associated with a lower risk of developing sarcopenia after surgery compared to open esophagectomy (OE) for esophageal cancer. These findings provide new evidence to support the use of robotic surgery in the multimodal therapy of EC.
JOURNAL OF THORACIC ONCOLOGY
(2023)
Article
Urology & Nephrology
Marie Mermier, Pierre Baron, Mathieu Roumiguie, Anne-Sophie Bajeot, Geraldine Pignot, Francois Lannes, Guillaume Ploussard, Anis Gasmi, Karim Bensalah, Ophelie Perrot, Morgan Roupret, Franck Bruyere, Benjamin Pradere, Gregory Verhoest
Summary: This study aims to identify protective and risk factors for early postoperative complications after robot-assisted radical cystectomy (RARC) for urothelial bladder carcinoma. The study found that factors such as anticoagulant therapy, ureteroenteric anastomosis-type, tobacco consumption, and opioid-free analgesia (OFA) were associated with the occurrence of early postoperative complications. However, complete intracorporeal diversion was found to be a protective factor.
JOURNAL OF ENDOUROLOGY
(2022)
Article
Nutrition & Dietetics
Sharon Cohen, Jonathan Gal, Yuval Freifeld, Sobhi Khoury, Yoram Dekel, Azik Hofman, Kamil Malshi, Gilad Amiel, Itay Sagi, Ilan Leibovici, Shay Golan, Jack Baniel, Barak Rozenzweig, Zohar Dotan, Miki Haifler
Summary: The study found that NAC-related nutritional deterioration is associated with an increased risk of complications after radical cystectomy. Therefore, nutritional intervention during neoadjuvant chemotherapy prior to radical cystectomy may be necessary.
Review
Urology & Nephrology
Paola Irene Ornaghi, Luca Afferi, Alessandro Antonelli, Maria Angela Cerruto, Katia Odorizzi, Alessandra Gozzo, Livio Mordasini, Agostino Mattei, Philipp Baumeister, Julian Cornelius, Alessandro Tafuri, Marco Moschini
Summary: High BMI, hypoalbuminemia, and sarcopenia significantly increased the complication rate after RC. Hypoalbuminemia predicted worse 3 year OS and sarcopenia predicted unfavorable 5 year CSS and OS. Preoperative assessment of RC patients' nutritional status is a useful tool to predict perioperative and survival outcomes.
WORLD JOURNAL OF UROLOGY
(2021)
Article
Oncology
Romain Geiss, Lucrezia Sebaste, Remi Valter, Johanne Poisson, Soraya Mebarki, Catherine Conti, Dimitri Vordos, Michael Bringuier, Arnaud Mejean, Pierre Mongiat-Artus, Tristan Cudennec, Florence Canoui-Poitrine, Philippe Caillet, Elena Paillaud
Summary: Radical cystectomy in older patients may have an increased risk of post-operative complications, with factors such as frailty, anemia, loss of autonomy, and severe comorbidities affecting the likelihood of being discharged home at one month post-surgery.
Article
Oncology
Aleksander Slusarczyk, Piotr Zapala, Tomasz Piecha, Lukasz Zapala, Tomasz Borkowski, Piotr Radziszewski
Summary: The study found that patients who underwent radical nephroureterectomy for upper urinary tract urothelial cancer after radical cystectomy experienced poor overall survival and cancer-specific survival, with most surgeries being performed for locally advanced tumors. Independent risk factors for worse survival included UTUC T stage, presence of metastasis, and male gender.
ANNALS OF SURGICAL ONCOLOGY
(2023)