Article
Oncology
Feng Pi, Gang Tang, Chaozheng Xie, Yukun Cao, Shilai Yang, Zhengqiang Wei
Summary: This study found that lymph node ratio is a strong predictor of stage III rectal cancer recurrence and suggests that Carbon Nanoparticles use significantly affects lymph node ratio and tumor recurrence.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Jinyoung Kim, Jun Park, Hyunju Park, Min Sun Choi, Hye Won Jang, Tae Hyuk Kim, Sun Wook Kim, Jae Hoon Chung
Summary: The study suggests using the metastatic lymph node ratio (LNR) as a quantitative evaluation tool for lymph node metastasis in patients with medullary thyroid cancer (MTC), which can potentially predict structural recurrence.
Article
Multidisciplinary Sciences
Annabelle Greenwood, John Keating, Diane Kenwright, Ali Shekouh, Alex Dalzell, Elizabeth Dennett, Kirsty Danielson
Summary: The study found that variation in B-cell compartments of tumour-draining lymph nodes is associated with clinicopathological risk factors in stage II colorectal cancer patients, such as T stage, carcinoembryonic antigen levels, deficiency in mismatch repair proteins, and lymphatic invasion.
Article
Gastroenterology & Hepatology
Hongjiang Pu, Xiaolin Pang, Jiangping Fu, Rui Zheng, Yaxue Chen, Dafu Zhang, Xiangdong Fang
Summary: The study found that the number of tumor deposits is closely associated with the risk of recurrence in patients with stage III CRC, especially in those with more than 4 tumor deposits. Therefore, it is important to incorporate both the number of tumor deposits and the number of lymph node metastases to assess patients' prognostic risk.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2022)
Article
Oncology
Goksen Inanc Imamoglu, Arzu Oguz, Sanem Cimen, Tuelay Eren, Cengiz Karacin, Dilsen Colak, Mustafa Altsbas, Sema Turker, Dogan Yazilita
Summary: The study found that positive lymph node ratio (PLNR) is a significant prognostic factor for survival in Stage III colorectal cancer patients, with a ratio above 0.31 indicating a poor prognosis. Prospective trials with larger patient groups are needed to further validate the role of PLNR as a prognostic indicator.
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
(2021)
Article
Oncology
Filipa Macedo, Hugo Sequeira, Katia Ladeira, Nuno Bonito, Charlene Viana, Sandra Martins
Summary: The lymph node ratio (LNR) may be a better prognostic indicator than pN categories in colon cancer patients. Total number of dissected lymph nodes is significantly correlated with pN, but not with LNR.
Article
Medicine, General & Internal
Xiang Zhang, Nan Feng, Bo Wu, Yiping Wei, Wenxiong Zhang
Summary: Lymph node ratio (LNR) is an important prognostic indicator in non-small-cell lung cancer (NSCLC), with higher LNR indicating worse prognosis. This study found that LNR and positive node category have predictive value for prognosis in stage III NSCLC patients.
Article
Medicine, General & Internal
Haixia Cui, Yuan Huang, Weibo Wen, Xiangdan Li, Dongyuan Xu, Lan Liu
Summary: This study found through meta-analysis that high lymph node ratio (LNR) is an adverse prognostic factor for cervical cancer (CC). The median LNR of approximately 0.0625 and 0.066 was identified as a prominent risk factor. Further clinical studies are needed to validate whether LNR can independently predict CC prognosis.
Article
Medicine, General & Internal
Lei Chen, Funing Yang, Zhaoyan Qi, Jiandong Tai
Summary: Tumor budding (TB), a powerful predictor of colorectal cancer (CRC), was studied to develop a prediction model for lymph node metastasis (LNM) and local recurrence in pT1 CRC patients. Independent predictors for LNM and recurrence were identified and used to construct predictive nomograms for treatment decision-making. The models showed potential clinical application value and postoperative chemotherapy was associated with better outcomes in high-risk patients.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Emir Capkinoglu, Aydin Eray Tufan, Sinan Omeroglu, Mert Tanal, Onur Guven, Uygar Demir
Summary: This study aims to evaluate the prognostic significance of positive lymph nodes following surgery in patients with gastric adenocarcinoma. A total of 193 patients who underwent curative gastrectomy were included in this retrospective study. The results suggest that the positive lymph node ratio has some predictive value for prognosis in these patients.
Article
Immunology
Hou-Qun Ying, Yu-Cui Liao, Fan Sun, Hong-Xin Peng, Xue-Xin Cheng
Summary: The study compared various inflammation-based biomarkers for predicting recurrence-free survival in stage II-III colorectal cancer patients and found that the platelet to lymphocyte ratio, lymphocyte to monocyte ratio, and other markers were related to patient outcomes. However, only certain markers remained independent predictors in multivariate analysis. The fibrinogen and neutrophil to lymphocyte ratio score emerged as a superior prognostic indicator, particularly for predicting recurrence in surgical CRC patients.
JOURNAL OF INFLAMMATION RESEARCH
(2021)
Article
Medicine, General & Internal
Yerim Cho, Su Bee Park, Jin Young Yoon, Min Seob Kwak, Jae Myung Cha
Summary: This study aimed to investigate the prognostic role of the neutrophil-to-lymphocyte ratio (NLR) in stage II to III colorectal cancer (CRC) patients who underwent surgery. The results showed that NLR was significantly associated with overall survival (OS) and could be used as a simple and useful parameter for predicting OS in these patients.
Article
Oncology
Jae Hyun Kim, Jongwook Yu, Dong Keon Kim, Seunghun Lee, Seung Hyun Lee, Byung Kwon Ahn, Tae Il Kim, Seun Ja Park
Summary: This study suggests that the tumor microbiome may be a potential predictor of postoperative disease recurrence in patients with colorectal cancer. The microbial diversity and abundance differ between tumor and adjacent tissues, and a prediction model using tumor tissue microbiome data performs better than clinical factors, especially in female patients.
FRONTIERS IN ONCOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Hao Yang, Tonghua Mei
Summary: The study found that in surgically resected stage I-III small-cell lung cancer patients, LNR <= 0.15 was associated with better survival rates, while LNR > 0.15 was associated with poorer survival rates. The predictive value of LNR should be further validated in prospective studies.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)
Article
Gastroenterology & Hepatology
Taketo Sasaki, Kohei Shigeta, Koji Okabayashi, Masashi Tsuruta, Ryo Seishima, Shimpei Matsui, Yuko Kitagawa
Summary: This study retrospectively analyzed 189 colorectal cancer patients who underwent curative resection, and found that horizontal spread of lymph node metastasis is an independent risk factor for recurrence.
COLORECTAL DISEASE
(2021)
Article
Dentistry, Oral Surgery & Medicine
Fadi I. Daher, Habib L. Abi-Aad, Hani I. Dimassi, Nadim Z. Baba, Zeina AK. Majzoub
Summary: The study aimed to assess the primary and secondary stability of variable-thread tapered implants in the posterior maxilla, and analyze the impact of various factors on implant stability quotients. The results showed that measurement direction and time are the most significant parameters affecting the stability quotients of these implants in the posterior maxilla.
JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY
(2021)
Article
Environmental Sciences
Hani Dimassi, Soumana C. Nasser, Aline Issa, Sarine S. Adrian, Bassima Hazimeh
Summary: This study aimed to measure HRQoL in Lebanese patients and determine factors affecting health utility scores. Results showed that participants rated their health and treatment satisfaction relatively high, with an average utility score of 0.762. Factors such as number of prescribed medications, age, and recent hospitalization significantly influenced HRQoL.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Multidisciplinary Sciences
Ahmad Saleh, Zeynep Burcu Akkus-Dagdeviren, Julian David Friedl, Patrick Knoll, Andreas Bernkop-Schnuerch
Summary: The aim of this study was to develop nanoparticles that can release drugs directly on the epithelium of the intestinal mucosa. These nanoparticles were prepared by using ionic gelation between chitosan and polyphosphate. The characteristics of the nanoparticles were analyzed, and their drug release ability and cytotoxicity were evaluated. The results showed that these nanoparticles have the potential to deliver drugs on the absorption membrane without causing toxicity.
Article
Medicine, General & Internal
Ahmad M. Saleh, Saud M. Alrawaili, Mohamed A. El-Sakhawy, Walid Kamal Abdelbasset
Summary: The study aimed to assess the knowledge of palliative care among nursing home staff. The results showed a low level of knowledge about palliative care in nursing homes in Jordan, highlighting the need for enhanced education and training to address the knowledge gaps.
AFRICAN HEALTH SCIENCES
(2022)
Article
Medicine, General & Internal
Ahmad M. Saleh, Saud M. Alrawaili, Walid Kamal Abdelbasset
Summary: The purpose of this study was to evaluate hand hygiene practices among Jordanian nurses working in hospitals. The study found that the majority of nurses had good hand hygiene practices, with a higher percentage seen among female nurses. Educational interventions and visual aids, such as posters, are needed to improve compliance with hand hygiene practices.
AFRICAN HEALTH SCIENCES
(2022)
Article
Infectious Diseases
Mohamad Fleifel, Jonathan Mina, Tony Haykal, Rana Asmar, Ghida El Hout, Ranime Harb, Hani Dimassi, Jacques Mokhbat, Anna Farra, Rola Husni-Samaha
Summary: This study retrospectively analyzed the treatment of COVID-19 inpatients and found that patients receiving high dose vitamin C intravenous injection often experienced dyspnea and desaturation, and were more likely to require oxygen therapy. In comparison, patients treated with remdesivir were more likely to be discharged after clinical improvement. The study concludes that further research is needed to establish local guidelines for the treatment of COVID-19.
JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
(2022)
Article
Medicine, General & Internal
Ahmad Mahmoud Saleh, Shamweel Ahmad, Hiba Shamweel, Mohammad H. Abuadas
Summary: This study aimed to assess the knowledge of Needle Stick Injury (NSI) among student nurses in Jordan and analyze its incidence and post-exposure management. A total of 130 student nurses from one hospital in Jordan participated in this descriptive cross-sectional study. Results showed that the participants had a good understanding of NSI, with an average knowledge score of 8 out of 10. Majority of the students (82%) reported experiencing at least one NSI exposure, but a significant number did not disclose it to their clinical professors or file incident reports. The study suggests the need for strengthening NSI education in nursing courses and improving student safety and post-exposure therapy during clinical practice.
RAWAL MEDICAL JOURNAL
(2023)
Article
Medicine, General & Internal
Ahmad Mahmoud Saleh
Summary: Objective of this study was to evaluate the knowledge of Jordanian nurses about evidenced based practice. The study included 120 Jordanian nurses from one private hospital in Amman, Jordan. Data was collected using an evidenced-based practice knowledge tool. Out of 120 nurses, 100 responded to the survey, resulting in a response rate of 83%. The results showed that knowledge regarding evidenced based practice was low, with an average score of 1.2 out of 10. Therefore, an evaluation is needed to improve the knowledge and skills of nurses.
RAWAL MEDICAL JOURNAL
(2023)
Meeting Abstract
Oncology
Mohammed Almahmodi, Nahla Mobark, Demah A. Almowanes, Haya N. Alghunaim, Nad E. Kattan, Ahmad M. Saleh, Wael Abdel Rahman Aljabarat, Fahad Alotabi, Maqsood Ahmad, Amal S. Alyahya, Ayman Al Banyan, Abdulelah A. Alluhaybi, Mohammed Rayis, Zaid G. Alnaqib, Ali Abdullah O. Ali Abdullah O. Balbaid, Amal Abdulsami S. Marie, Eric Bouffet, Musa Alharbi
PEDIATRIC BLOOD & CANCER
(2022)
Article
Medicine, General & Internal
Rahaf F. Alkahtani, Abdulrahman A. Alomar, Abdulrahman F. Alkanhal, Mohammed F. Alhinti, Shahad E. Alatoui, Rinad R. Alrashidi, Ahmad Saleh
Summary: This study investigated the prevalence of sleep disturbance and psychological impact during the spread of COVID-19 in Riyadh, Saudi Arabia. The results showed a high prevalence of poor sleep quality and worsening mental health, highlighting the need for increased awareness, screening, and management of sleep quality and mental health.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Meeting Abstract
Cardiac & Cardiovascular Systems
Harshith P. Chandrakumar, Anoop V. Puskoor, Seeta Chillumuntala, Sara Sharif, Diego Cepeda Mora, Tanuj Gupta, Ashkan Tadayoni, Pelin Celiker, Stephanie Yakoubovitch, Andrew Tsai, Courtney Chiu, Anan Kazi, Michael Frielich, Ahmad Saleh, Seung Jae Moon, Kingsley Cruickshank, Julie Katz, Louis Salciccioli, Isabel M. McFarlane
Article
Medicine, General & Internal
Elturabi Elsayed Ebrahim, Ahmad M. Saleh
Summary: COVID-19 is a dangerous epidemic that has claimed lives worldwide. A study was conducted to evaluate knowledge levels among participants, showing that while most people have good knowledge about the cause of COVID-19 and some symptoms, there is a lack of knowledge about transmission modes. Educational workshops are recommended to enhance knowledge and prevent the spread of the virus.
PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES
(2021)
Article
Health Care Sciences & Services
Safraz Hamid, Frederic Joyce, Aaliya Burza, Billy Yang, Alexander Le, Ahmad Saleh, Robert S. Poston
Summary: The transfer of a cardiac surgery patient from the OR to the ICU is a critical and challenging process, with the information exchange known as 'handoff' being a key focus for improving patient safety. A quality improvement project was conducted to develop a new handoff protocol involving the ICU team receiving face-to-face handoff, observing the final minutes of the case, and participating in debrief discussions, resulting in increased positive response rates for handoff safety questions. This initiative showed that having the ICU team run in parallel with the cardiac surgical team positively affects safety culture.
Article
Medicine, General & Internal
Elturabi Elsayed Ebrahim, Ahmad M. Saleh
PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES
(2020)
Article
Multidisciplinary Sciences
Nazim Karalezli, Ozge Ipek, Ahmad M. Saleh
