Article
Microbiology
Zhuoru Jiang, Ping Jiang, Siqi Ji, Dan Su, Guifang Xu, Mingming Zhang
Summary: Limosilactibacilus reuteri is a probiotic that can improve health or aggravate diseases by directly regulating the gut microbiota and secreting substances. Current research shows that it is mostly beneficial for human health, but further studies are needed to determine its role in probiotics.
MICROBIOLOGICAL RESEARCH
(2023)
Article
Horticulture
Huaying Liu, Ruili Zhang, Qiuqin Zhang, Mengtian Tian, Xiaopu Ren, Libin Wang, Xiaohong Wang
Summary: This study aimed to evaluate the antimicrobial activity of cell-free supernatants (CFS) produced by Lactobacillus pentosus 86 against A. gaisen. Results showed that CFS displayed excellent thermos and enzymatic stabilities with an antifungal activity over 85%. CFS inhibited the mycelial growth of A. gaisen by destroying the hyphae membrane, leading to leakage of nucleic acids and proteins, collapse and shrinkage of hyphae, and changes in spore morphology.
Article
Biotechnology & Applied Microbiology
Nuanyi Liang, Vera Neuzil-Bunesova, Vaclav Tejnecky, Michael Ganzle, Clarissa Schwab
Summary: Strains of Limosilactobacillus reuteri are used in food preservation due to their production of fermentation metabolites lactic and acetic acid, as well as the antimicrobial reuterin. This study reveals that besides reuterin, these strains also synthesize 3-HP, with stronger antibacterial activity at pH 4.8. Gram-positive bacteria show higher resistance to 3-HP and propionic acid compared to Gram-negative bacteria, and acrolein enhances the antibacterial activity of 3-HP.
Review
Food Science & Technology
Emma Mani-Lopez, Daniela Arrioja-Breton, Aurelio Lopez-Malo
Summary: This review summarizes the research progress and findings on the antimicrobial activity, mechanism of action, stability, cytotoxicity, and safety of LAB CFS. Studies have shown that CFS exhibits good antibacterial and antifungal activity, strong inhibition of microorganisms in foods, and no toxicity to human cells. However, further research is needed to investigate the stability and cytotoxic effects of CFS.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2022)
Article
Geriatrics & Gerontology
Hye-Yeon Lee, Ji-Hyeon Lee, Seung Hyung Kim, Su-Yeon Jo, Kyung-Jin Min
Summary: This study evaluated the anti-aging effects of Lactobacillus reuteri on the lifespan and physiology of fruit flies. It found that L. reuteri significantly increased the mean lifespan of fruit flies without affecting reproductive output, food intake, or locomotor activity. The study suggests that the longevity effect of L. reuteri is mediated by the reduction of the insulin/IGF-1 signaling pathway and the action of reuterin.
Article
Geriatrics & Gerontology
Hye-Yeon Lee, Ji-Hyeon Lee, Seung Hyung Kim, Su-Yeon Jo, Kyung-Jin Min
Summary: This study found that L. reuteri has anti-aging effects and can significantly extend the average lifespan of fruit flies. Furthermore, the effects of L. reuteri do not affect the reproductive output, food intake, or locomotor activity of fruit flies. The results suggest that the anti-aging effects of L. reuteri are mediated by the reduction of the insulin/IGF-1 signaling pathway and the action of reuterin.
Article
Microbiology
Luca Spaggiari, Arianna Sala, Andrea Ardizzoni, Francesco De Seta, Dhirendra Kumar Singh, Attila Gacser, Elisabetta Blasi, Eva Pericolini
Summary: Vulvovaginal candidiasis (VVC) is a common condition caused by Candida species, with non-albicans Candida (NAC) species such as C. parapsilosis becoming increasingly prevalent. Lactobacilli may play a beneficial role in preventing C. parapsilosis infection by reducing its virulence traits and improving epithelial resistance.
MICROBIOLOGY SPECTRUM
(2022)
Article
Biotechnology & Applied Microbiology
Ji Yeon Lee, YongGyeong Kim, Ja- Kim, Hyang-Yeol Lee, Gi-Seong Moon, Chang-Ho Kang
Summary: CFS derived from Ligilactobacillus salivarius and Limosilactobacillus fermentum can enhance skin moisturization and improve the barrier function of keratinocytes, while also exerting antibacterial effects.
FERMENTATION-BASEL
(2022)
Article
Nutrition & Dietetics
Patricia Diez-Echave, Izaskun Martin-Cabrejas, Jose Garrido-Mesa, Susana Langa, Teresa Vezza, Jose M. Landete, Laura Hidalgo-Garcia, Francesca Algieri, Melinda J. Mayer, Arjan Narbad, Ana Garcia-Lafuente, Margarita Medina, Alba Rodriguez-Nogales, Maria Elena Rodriguez-Cabezas, Julio Galvez, Juan L. Arques
Summary: Limosilactobacillus reuteri INIA P572 shows high resistance to gastrointestinal conditions, can grow and produce reuterin in a human colonic model, and exhibits clear immunomodulatory and protective effects in a DSS-induced colitic mice model.
Article
Microbiology
Marina Scillato, Ambra Spitale, Gino Mongelli, Grete Francesca Privitera, Katia Mangano, Antonio Cianci, Stefania Stefani, Maria Santagati
Summary: The study found that Lactobacilli in healthy vaginal microbiota exhibit strong intervention and co-aggregation abilities against urogenital pathogens, making them potential candidates for a new vaginal probiotic formulation against infections. However, further in vivo studies are needed to assess their actual health benefits for humans in clinical situations.
Article
Food Science & Technology
Clorinda Malmo, Irene Giordano, Gianluigi Mauriello
Summary: Microencapsulation technology can enhance the survival rate of Lactiplantibacillus plantarum 48M cells under gastrointestinal simulated conditions, allowing them to survive similarly to the probiotic strain Limosilactobacillus reuteri DSM 17938. However, microencapsulation does not provide protection for either strain when exposed to heat treatments.
Article
Biotechnology & Applied Microbiology
Yuanze Sun, Noemi Gutierrez-Maddox, Anthony N. Mutukumira, Ian S. Maddox, Quan Shu
Summary: Limosilactobacillus reuteri DPC16 strain can secrete reuterin, a potentially valuable chemical and broad-spectrum antimicrobial substance. The study identified the most efficient conditions for reuterin production, which include a 20-hour growth of cells at 25 degrees C and pH 6.8, followed by a 2-hour fermentation of glycerol.
FERMENTATION-BASEL
(2022)
Review
Food Science & Technology
Mao-Cheng Sun, Zi-Yi Hu, Dian-Dian Li, Yu-Xin Chen, Jing-Hui Xi, Chang-Hui Zhao
Summary: The reuterin system produced by Limosilactobacillus reuteri is a complex multi-component antimicrobial system with potential applications in the food and medical industries. It possesses various activities such as regulation of intestinal flora, anti-infection, anti-inflammatory, and anti-cancer effects. Although the antimicrobial mechanism and toxicity of the reuterin system are still unclear, this updated review provides valuable information on its biosynthesis, composition, production, mechanisms, stability, toxicity, and potential applications. Challenges and opportunities for using the reuterin system as a food preservative or health-promoting agent are also discussed.
Article
Chemistry, Medicinal
Yehui Gang, Tae-Yang Eom, Svini Dileepa Marasinghe, Youngdeuk Lee, Eunyoung Jo, Chulhong Oh
Summary: This study optimized the DPPH solvent and its water content to develop a method for screening antioxidants suitable for salt-containing samples, successfully identifying antioxidants for marine microorganisms and potential applications in salt-fermented foods.
Article
Veterinary Sciences
Thotsapol Kaewchomphunuch, Thunyathorn Charoenpichitnunt, Varissara Thongbaiyai, Natharin Ngamwongsatit, Kampon Kaeoket
Summary: The study demonstrates that antimicrobial peptides (AMPs) extracted from lactic acid bacteria can inhibit the growth of pathogenic E. coli isolated from pigs in Thailand, and the antimicrobial activity is time-dependent.
BMC VETERINARY RESEARCH
(2022)