Article
Food Science & Technology
Ricardo Vera-Bravo, Angela Hernandez, Steven Pena, Carolina Alarcon, Alix E. Loaiza, Crispin A. Celis
Summary: This study evaluated the adulteration of raw milk with cheese whey using HPLC marker, confirming the presence of cGMP in adulterated samples. The molecular exclusion chromatography technique presented is reliable, easy to implement, and cost-effective, allowing for routine quality control of milk.
Review
Nutrition & Dietetics
Tiantian Lin, Gopinathan Meletharayil, Rohit Kapoor, Alireza Abbaspourrad
Summary: Dairy products play a significant role in human health and immune function, containing bioactive components such as alpha-lactalbumin and lactoferrin. Challenges in isolating and purifying these components on an industrial scale, as well as their stability during processing, storage, and digestion, can be overcome with advanced technologies.
Review
Food Science & Technology
Eva Krolitzki, Sebastian P. Schwaminger, Moritz Pagel, Fabian Ostertag, Jorg Hinrichs, Sonja Berensmeier
Summary: Lactoferrin, a versatile protein found in mammals, is primarily isolated from bovine milk or sweet whey for industrial production and consumer goods applications. Established industrial productions focus on skim milk, but alternative approaches utilizing dairy by-products are also able to produce high-quality lactoferrin.
INTERNATIONAL DAIRY JOURNAL
(2022)
Article
Food Science & Technology
Maria Romo, Massimo Castellari, Dinar Fartdinov, Xavier Felipe
Summary: In this study, high-pressure processing was used to remove beta-Lactoglobulin from bovine native whey concentrate and generate an enriched alpha-Lactalbumin fraction. The optimal conditions for alpha-Lactalbumin yield and purification degree were determined. The results showed that high-pressure processing could improve the precipitation of beta-Lactoglobulin and the purification of alpha-Lactalbumin. Further characterization and application of membrane concentration and high-pressure processing are recommended for the valorization of cheese whey.
Review
Food Science & Technology
Jianxin Xiao, Jiaying Ma, Muhammad Zahoor Khan, Gibson Maswayi Alugongo, Tianyu Chen, Shuai Liu, Shengli Li, Zhijun Cao
Summary: Whey protein components have anticancer attributes and can reduce the risk of colorectal cancer. They have anti-inflammatory and antioxidant abilities and can induce apoptosis, inhibit tumor cell proliferation, and impede metastasis. Studies have shown the importance of incorporating whey protein components into a balanced daily diet for the prevention and treatment of colorectal cancer.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Medicine, General & Internal
Guo-Yue Wan, Ka-Man Lam, Ian-Ian Wong, Pedro Fong, Li-Rong Meng
Summary: This study extracted anti-H. pylori peptides from cow milk using in vitro methods and found that casecidin 17 and beta-casein 207-224 showed promising antibacterial effects. The extracts had the lowest minimum inhibitory concentration (MIC90) at low pH values.
ARCHIVES OF MEDICAL SCIENCE
(2022)
Article
Food Science & Technology
Nannan Wang, Tingting Cai, Xia Liu, Wanping Zhu
Summary: Helicobacter pylori (H. pylori) is associated with gastric mucosal injury, gastric ulcer, and other gastrointestinal diseases. Resistance to antibiotics has become a hindrance to clinical eradication therapy. Bovine lactoferrin (bLF) has a broad-spectrum antibacterial effect and may help improve the problem of antibiotic resistance. In vitro and in vivo experiments demonstrated that bLF has a significant bactericidal effect on resistant H. pylori and can improve gastric mucosal injury.
INTERNATIONAL DAIRY JOURNAL
(2023)
Article
Agriculture, Dairy & Animal Science
Hirofumi Fukudome, Toshiyuki Yamaguchi, Junichi Higuchi, Akihiro Ogawa, Yuichi Taguchi, Juan Li, Toshihide Kabuki, Koutaro Ito, Fumihiko Sakai
Summary: In this study, a sialylglycopeptide concentrate (SGC) was prepared from whey protein concentrate containing GMP by proteolytic digestion and ultrafiltration. The SGC contained abundant O-glycans, including N-acetylneuraminic acid, N-acetylgalactosamine, and galactose, and exhibited bifidogenic activity in promoting the growth of certain species of bifidobacteria. The preparation protocol for SGC was relatively simple and high-yield, making it suitable for large-scale production.
JOURNAL OF DAIRY SCIENCE
(2021)
Review
Microbiology
Ichiro Imoto, Taro Yasuma, Corina N. D'Alessandro-Gabazza, Satoko Oka, Moriharu Misaki, Noriyuki Horiki, Esteban C. Gabazza
Summary: Helicobacter pylori is the main causative agent of gastroduodenal diseases, and its eradication has become challenging due to the emergence of antibiotic-resistant strains. Lactoferrin, an iron-binding protein, has shown antimicrobial properties and its concentrations increase during H. pylori infection. Although lactoferrin alone cannot eradicate H. pylori, recent studies have explored the potential of oral lactoferrin supplementation as a part of eradication therapy.
Review
Chemistry, Analytical
Jelena Radosavljevic, Dragana Stanic-Vucinic, Marija Stojadinovic, Mirjana Radomirovic, Ana Simovic, Milica Radibratovic, Tanja Cirkovic Velickovic
Summary: Whey protein, an important source of nutrition and biotechnology, is considered a by-product of the dairy industry due to low economic value. The challenge in whey protein separation lies in low concentration and similar properties. Ion exchange techniques are widely used for separation, and recent research on ion exchange membranes shows promise for industrial application. Adsorption-based methodologies targeting protein structure differences are anticipated to further improve whey protein separation.
CURRENT ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Applied
Thomas Valente De Oliveira, Marcelo Depolo Poleto, Samuel Vieira Barbosa, Jane Selia dos Reis Coimbra, Eduardo Basilio De Oliveira
Summary: Computational molecular dynamics was used to analyze the molecular conformations of bovine alpha-lactalbumin at different temperatures, showing that the absence of Ca2+ triggered significant protein conformation changes and affected the foaming properties. This study demonstrates the power of MD in providing insights into the molecular origins of food protein functionalities.
Article
Agriculture, Multidisciplinary
Yu Lu, Jie Liu, Zhenhua Li, Wenqing Li, Jing Liu, Linjuan Huang, Zhongfu Wang
Summary: This study analyzed the O-glycan modifications of casein glycomacropeptide from bovine and caprine whey powder and compared their immune activities and regulatory mechanisms. The results showed that bovine glycomacropeptide had a higher content of O-glycans, especially disialylated ones, which promoted immune activity. Both bovine and caprine glycomacropeptide significantly upregulated the expression of immune-related genes and activated the MAPK immunomodulatory signaling pathway.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Review
Food Science & Technology
Thao M. Ho, Bhesh R. Bhandari, Nidhi Bansal
Summary: Factors such as protein content, processing conditions, and foaming methods have a significant impact on the foam quality of dairy products, particularly in terms of their appearance, texture, and stability. This review comprehensively discusses the functionality of milk proteins in producing and stabilizing foam under the influence of these factors, highlighting the challenges faced by researchers and the dairy industry in controlling the foaming process of milk for specific applications.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Nutrition & Dietetics
Eric Guillemard, Marion Poirel, Florent Schafer, Laurent Quinquis, Caroline Rossoni, Christian Keicher, Frank Wagner, Hania Szajewska, Frederic Barbut, Muriel Derrien, Peter Malfertheiner
Summary: The study showed that consumption of a multi-strain fermented milk in patients under Hp treatment can lead to a modest but significant faster recovery of the gut microbiota composition and production of short chain fatty acids, while limiting the increase of potentially pathogenic bacteria.
Article
Nutrition & Dietetics
Jian Zhang, Ai Zhao, Shiyun Lai, Qingbin Yuan, Xiaojiang Jia, Peiyu Wang, Yumei Zhang
Summary: The study investigated the changes in multiple human milk proteins during the first six months of lactation, finding that their concentrations decreased over time. Factors like maternal age and mode of delivery were found to impact these changes. Additionally, the concentration of alpha(s-1) casein in milk was inversely associated with infant weight, suggesting that milk protein composition may influence infant growth.
Letter
Obstetrics & Gynecology
J. Nagpal, A. Bhartia
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2015)
Review
Medicine, General & Internal
Louise A. Beveridge, Allan D. Struthers, Faisel Khan, Rolf Jorde, Robert Scragg, Helen M. Macdonald, Jessica A. Alvarez, Rebecca S. Boxer, Andrea Dalbeni, Adam D. Gepner, Nicole M. Isbel, Thomas Larsen, Jitender Nagpal, William G. Petchey, Hans Stricker, Franziska Strobel, Vin Tangpricha, Laura Toxqui, M. Pilar Vaquero, Louise Wamberg, Armin Zittermann, Miles D. Witham
JAMA INTERNAL MEDICINE
(2015)
Article
Obstetrics & Gynecology
J. Nagpal, A. Sachdeva, R. Sengupta Dhar, V. L. Bhargava, A. Bhartia
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2015)
Article
Nursing
Andrew Symon, Jitender Nagpal, Irena Maniecka-Bryla, Agata Nowakowska-Glab, Arash Rashidian, Roghayeh Khabiri, Isabel Mendes, Ana Karina Bezerra Pinheiro, Mirna Fontenele de Oliveira, Liping Wu
JOURNAL OF ADVANCED NURSING
(2013)
Article
Medicine, General & Internal
Jitender Nagpal, Manu Raj Mathur, Swapnil Rawat, Deepti Nagrath, Charlotte Lee, Atul Singhal, Michelle Heys, Mario Cortina Borja, Katrin Augustin, Jageshwor Gautam, Rajendra Pant, Laura Swabey, Monica Lakhanpaul
Article
Endocrinology & Metabolism
Jitender Nagpal, Swapnil Rawat, Siddhi Goyal, Anthikad S. Lata
Summary: The study found that the quality of care for known diabetes patients in Delhi is poor, with inadequate glycemic control, lipid control, and blood pressure management. There is a significant gap between practice recommendations and the delivery of diabetes care in Delhi.
Article
Medicine, Research & Experimental
Jitender Nagpal, Swapnil Rawat, Lovely Gupta, Avantika Negi, Divya Shashi Oraon
Summary: This study aims to develop a diabetes self-management education training kit, understand barriers to implementation, and evaluate the effectiveness and sustainability of community leader-based rollout.
Article
Endocrinology & Metabolism
Swapnil Rawat, Ramasheesh Yadav, Siddhi Goyal, Jitender Nagpal
Summary: The research highlights the high cardiovascular risk faced by diabetes patients in Delhi, including increased risks of coronary heart disease, stroke, and cardiovascular fatality. There is room for improvement in the treatment and management of these patients.
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS
(2023)
Article
Health Care Sciences & Services
Neha Joshi, Rakhi Wadhwani, Jitender Nagpal, Saru Bhartia