Mode of action of agomelatine: Synergy between melatonergic and 5-HT2Creceptors

Cell “circadian” cycle: New role for mammalian core clock genes

(2011) Laurence Borgs et al.   CELL CYCLE

Melatonin and the Metabolic Syndrome: Physiopathologic and Therapeutical Implications

(2011) Daniel P. Cardinali et al.   NEUROENDOCRINOLOGY

Blockade of stress-induced increase of glutamate release in the rat prefrontal/frontal cortex by agomelatine involves synergy between melatonergic and 5-HT2C receptor-dependent pathways

(2010) Daniela Tardito et al.   BMC NEUROSCIENCE

Agomelatine in the Treatment of Major Depressive Disorder

(2010) Sidney H. Kennedy et al.   CNS DRUGS

The pharmacological properties of antidepressants

(2010) Giorgio Racagni et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Efficacy of the Novel Antidepressant Agomelatine on the Circadian Rest-Activity Cycle and Depressive and Anxiety Symptoms in Patients With Major Depressive Disorder

(2010) Siegfried Kasper et al.   JOURNAL OF CLINICAL PSYCHIATRY

GSK-3  Inhibits Presynaptic Vesicle Exocytosis by Phosphorylating P/Q-Type Calcium Channel and Interrupting SNARE Complex Formation

(2010) L.-Q. Zhu et al.   JOURNAL OF NEUROSCIENCE

Acute Stress Increases Depolarization-Evoked Glutamate Release in the Rat Prefrontal/Frontal Cortex: The Dampening Action of Antidepressants

(2010) Laura Musazzi et al.   PLoS One

Melatonin—A pleiotropic, orchestrating regulator molecule

(2010) Rüdiger Hardeland et al.   PROGRESS IN NEUROBIOLOGY

Modulation of neuroplastic molecules in selected brain regions after chronic administration of the novel antidepressant agomelatine

(2010) Francesca Calabrese et al.   PSYCHOPHARMACOLOGY

Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration

(2010) Raffaella Molteni et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Proteomic Analysis Reveals the Role of Synaptic Vesicle Cycling in Sustaining the Suprachiasmatic Circadian Clock

(2009) Michael J. Deery et al.   CURRENT BIOLOGY

The neurobiology of circadian rhythms

(2009) Eddy A Van der Zee et al.   CURRENT OPINION IN PULMONARY MEDICINE

Circuit projection from suprachiasmatic nucleus to ventral tegmental area: a novel circadian output pathway

(2009) Alice H. Luo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

P.1.c.014 The novel antidepressant, agomelatine, blocks cerebral 5-HT2C receptors in vivo: a phMRI challenge study in rats

(2009) I. Linnik et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The NGF saga: From animal models of psychosocial stress to stress-related psychopathology

(2009) Francesca Cirulli et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Early induction of CREB activation and CREB-regulating signalling by antidepressants

(2009) Daniela Tardito et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice

(2009) Eleni Païzanis et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Mechanisms Contributing to the Phase-Dependent Regulation of Neurogenesis by the Novel Antidepressant, Agomelatine, in the Adult Rat Hippocampus

(2009) Amélie Soumier et al.   NEUROPSYCHOPHARMACOLOGY

Brain Clocks: From the Suprachiasmatic Nuclei to a Cerebral Network

(2009) Jorge Mendoza et al.   NEUROSCIENTIST

The regulation of central and peripheral circadian clocks in humans

(2009) N. Cermakian et al.   Obesity Reviews

Bidirectional communication between sleep and circadian rhythms and its implications for depression: Lessons from agomelatine

(2009) Seithikurippu R. Pandi-Perumal et al.   PROGRESS IN NEUROBIOLOGY

Circadian misalignment in major depressive disorder

(2009) Jonathan Emens et al.   PSYCHIATRY RESEARCH

Neuronal plasticity: A link between stress and mood disorders

(2009) Francesca Calabrese et al.   PSYCHONEUROENDOCRINOLOGY

A phase advance of the light-dark cycle stimulates production of BDNF, but not of other neurotrophins, in the adult rat cerebral cortex: association with the activation of CREB

(2008) Ritsuko Katoh-Semba et al.   JOURNAL OF NEUROCHEMISTRY

The Immediate Early Gene Arc/Arg3.1: Regulation, Mechanisms, and Function

(2008) C. R. Bramham et al.   JOURNAL OF NEUROSCIENCE

Circadian oscillation of hippocampal MAPK activity and cAMP: implications for memory persistence

(2008) Kristin L Eckel-Mahan et al.   NATURE NEUROSCIENCE

Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

(2008) Gerard Sanacora et al.   NATURE REVIEWS DRUG DISCOVERY

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS

Repeated administration of imipramine attenuates glutamatergic transmission in rat frontal cortex

(2008) K. Tokarski et al.   NEUROSCIENCE

S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models

(2008) Anne Dekeyne et al.   PSYCHOPHARMACOLOGY