Article
Microbiology
David M. P. De Oliveira, Brian M. Forde, Minh-Duy Phan, Bernhard Steiner, Bing Zhang, Johannes Zuegg, Ibrahim M. El-deeb, Gen Li, Nadia Keller, Stephan Brouwer, Nichaela Harbison-Price, Amanda J. Cork, Michelle J. Bauer, Saleh F. Alquethamy, Scott A. Beatson, Jason A. Roberts, David L. Paterson, Alastair G. McEwan, Mark A. T. Blaskovich, Mark A. Schembri, Christopher A. McDevitt, Mark von Itzstein, Mark J. Walker
Summary: This study explores the use of PBT2 to break the resistance of A. baumannii to tetracycline class antibiotics, showing promising results in both in vitro and in vivo experiments.
Article
Microbiology
David M. P. De Oliveira, Brian M. Forde, Minh-Duy Phan, Bernhard Steiner, Bing Zhang, Johannes Zuegg, Ibrahim M. El-Deeb, Gen Li, Nadia Keller, Stephan Brouwer, Nichaela Harbison-Price, Amanda J. Cork, Michelle J. Bauer, Saleh F. Alquethamy, Scott A. Beatson, Jason A. Roberts, David L. Paterson, Alastair G. McEwan, Mark A. T. Blaskovich, Mark A. Schembri, Christopher A. McDevitt, Mark von Itzstein, Mark J. Walker
Summary: The study found that the combination of PBT2 and zinc with tetracycline class antibiotics can effectively combat multidrug-resistant A. baumannii, potentially serving as a treatment for overcoming strain resistance.
Article
Environmental Sciences
K. S. Stenger, O. G. Wikmark, C. C. Bezuidenhout, L. G. Molale-Tom
Summary: Microplastics pollution in marine environments is a growing concern, with microplastics persisting in the ocean and potentially influencing the ecosystem. The formation of biofilms on plastic surfaces may alter microbial communities and facilitate the spread of antibiotic resistance genes.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Silvia Bonetta, Andrea Di Cesare, Cristina Pignata, Raffaella Sabatino, Manuela Macri, Gianluca Corno, Marco Panizzolo, Sara Bonetta, Elisabetta Carraro
Summary: This study examines the fate of antibiotic resistance in the urban water cycle in Italy, focusing on the prevalence of antibiotic-resistant bacteria (ARB) and antibiotic-resistant genes (ARGs) in wastewater treatment plants (WWTPs) and drinking water treatment plants (DWTPs). Plate counting and quantitative real-time PCR (qPCR) were used to quantify ARB (resistant to tetracycline, ampicillin, and sulfonamides) and measure the abundance of selected ARGs. The results show higher concentrations of ARB and ARGs in WWTPs compared to DWTPs, indicating that WWTPs are hotspots for antibiotic resistance spread. Although significant reductions were observed after treatment, none of the detected ARB or ARGs were completely removed from drinking water. Therefore, it is important to integrate culture-dependent and culture-independent methods to investigate antibiotic resistance dynamics in aquatic ecosystems involved in the urban water cycle, and to monitor the presence of ARB and ARGs, especially in drinking water, as it represents a potential route of transmission to humans.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Xiuyun Zhao, Gaofu Qi, Yali Feng, Chenyang Du
Summary: The extensive use of antibiotics has led to the accumulation of antibiotic-resistant microorganisms and genes in environments, posing a threat to human health and environmental contamination. In this study, the effects of five years of nematicide avermectin application on the rhizosphere microbiome and resistome of sick tobacco plants were investigated. The application of avermectin increased the abundance and distribution of antibiotic-resistant bacteria and resistance genes in the soil.
ENVIRONMENTAL RESEARCH
(2023)
Article
Engineering, Environmental
Debanjali Dey, Shamik Chowdhury, Ramkrishna Sen
Summary: Antibiotic resistance is a major global crisis, with antibiotic resistant bacteria and genes detected as emerging biological contaminants. The release of antibiotic residue from human waste and pharmaceutical effluents into wastewater leads to the proliferation of resistance genes and bacteria in natural environments. Nanotechnology and nanomaterials offer potential solutions for combating antibiotic resistance, with ongoing efforts to develop efficient nanotechnology-based treatment strategies. However, the long-term efficacy of nano-based treatment under realistic conditions remains a challenge for commercialization. This review highlights the potential of nanotechnology in removing antibiotic resistance genes and bacteria, and discusses advanced detection technologies in use or being developed beyond the laboratory scale.
JOURNAL OF WATER PROCESS ENGINEERING
(2023)
Article
Engineering, Environmental
Yan Wang, Xiaoyu Ni, Xuan Hou, Defang Ma, Bo Zhang, Qian Li, Baoyu Gao
Summary: An electrified carbon nanotube membrane combined with chlorine disinfection was developed to effectively eradicate antibiotic-resistant bacteria and damage antibiotic resistance genes in water samples, providing a potential method for water and sewage treatment plants.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Miguel Herraiz-Carbone, Salvador Cotillas, Engracia Lacasa, Marina Vasileva, Caridad Sainz de Baranda, Eva Riquelme, Pablo Canizares, Cristina Saez
Summary: The study demonstrated the effectiveness of using MIKROZON (R) cell for disinfecting complex urine, achieving total disinfection and reducing the concentration of antibiotic resistance genes. This electrochemical technology could be a promising tool to reduce the risk of antibiotic resistance spread.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Xiaoyu Zhao, Haochang Su, Wujie Xu, Xiaojuan Hu, Yu Xu, Guoliang Wen, Yucheng Cao
Summary: This study investigated the inactivation and removal efficiencies of Escherichia coli and plasmid-encoded ARGs by three commonly used fishery oxidants. The results showed that these oxidants achieved sufficient CT values to completely inactivate the target substances, indicating efficient disinfection in water. This research provides insight into controlling the spread of ARGs and ARB in aquaculture through practical disinfection methods.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Shuai Zhang, Xingxiang Liu, Pengxiang Qiu, Bin Chen, Chenmin Xu, Weiliang Dong, Tao Liu
Summary: This study investigates the selective capture of antibiotic resistant genes (ARGs) and bacterial assemblages by different materials and sizes of microplastics (MPs). The results show that MPs can selectively enrich intracellular and extracellular ARGs, as well as affect the formation of bacterial communities in wastewater.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Quan Zheng, Yinqiao Zhang, Qianxin Zhang, Yujue Wang, Gang Yu
Summary: The electro-peroxone (EP) process is an electricity-based oxidation process that generates hydrogen peroxide (H2O2) from cathodic oxygen (O2) reduction to remove antibiotic resistant bacteria (ARB) and plasmid-encoded antibiotic resistance genes (ARGs). Compared to ozonation alone, the EP process exhibits higher center dot OH exposures but lower O3 exposures, resulting in a moderately decreased efficiency of ARB inactivation and ARG degradation. However, the EP process effectively cleaves plasmid DNA to shorter fragments, reducing the risks of natural transformation of ARGs. Consideration of the effects of the EP process on ARB and ARG inactivation is important for water treatment implementation.
Article
Environmental Sciences
Shuai Zhang, Yu Zhang, Yue Wang, Xingxiang Liu, Muyu Li, Hao Fang, Ming Kong
Summary: Surface runoff is a main pathway for emerging pollutants, including antibiotics, antibiotic-resistant bacteria, and antibiotic resistance genes, to enter marine sediments. This study investigates the impact of emerging pollutants on the fate of antibiotic resistance genes in marine sediments from different seas in China. The results show that antibiotic exposure generally decreases the relative abundance of most antibiotic resistance genes, but there are exceptions with increased abundance observed in certain conditions. The findings suggest that dosing with emerging pollutants does not increase antibiotic resistance gene abundance in marine sediments.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Environmental
Hu Li, Zhao Kang, Enli Jiang, Ruiying Song, Ying Zhang, Guangzhou Qu, Tiecheng Wang, Hanzhong Jia, Lingyan Zhu
Summary: The study developed a novel strategy using plasma to simultaneously remove antibiotic-resistant Escherichia coli and its resistance genes, inhibiting gene transfer by conjugation. Plasma treatment effectively inactivated bacteria, reduced antibiotic resistance, and significantly decreased the presence of resistance genes, integron genes, and conjugative transfer frequency.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Engineering, Environmental
Hu Li, Ruiying Song, Yangyang Wang, Rongwei Zhong, Ying Zhang, Jian Zhou, Tiecheng Wang, Hanzhong Jia, Lingyan Zhu
Summary: This study successfully inactivated ARB, eliminated ARGs, and inhibited the transfer of ARGs using surface plasma, with the addition of NO3-, Cu2+, and Fe2+ found to promote these processes.
Review
Agricultural Engineering
Achmad Syafiuddin, Raj Boopathy
Summary: This article discusses the application of anaerobic sludge digestion (ASD) in treating sludge, recovering energy, and reducing antibiotic resistance genes (ARGs), highlighting the existing issues and challenges, and suggesting directions for further research.
BIORESOURCE TECHNOLOGY
(2021)