Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks

Cross-Species Regulatory Network Analysis Identifies a Synergistic Interaction between FOXM1 and CENPF that Drives Prostate Cancer Malignancy

(2014) Alvaro Aytes et al.   CANCER CELL

Identification of Causal Genetic Drivers of Human Disease through Systems-Level Analysis of Regulatory Networks

(2014) James C. Chen et al.   CELL

Role of Glutamatergic Projections from Ventral Tegmental Area to Lateral Habenula in Aversive Conditioning

(2014) D. H. Root et al.   JOURNAL OF NEUROSCIENCE

VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation

(2014) Taryn E Grieder et al.   NATURE NEUROSCIENCE

ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State

(2014) Yakov Chudnovsky et al.   Cell Reports

Operant alcohol self-administration in dependent rats: Focus on the vapor model

(2013) Leandro F. Vendruscolo et al.   ALCOHOL

Direct Reversal of Glucocorticoid Resistance by AKT Inhibition in Acute Lymphoblastic Leukemia

(2013) Erich Piovan et al.   CANCER CELL

ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1

(2013) Matthew D. Galbraith et al.   NUCLEIC ACIDS RESEARCH

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

(2013) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

Corticosteroid-Dependent Plasticity Mediates Compulsive Alcohol Drinking in Rats

(2012) L. F. Vendruscolo et al.   JOURNAL OF NEUROSCIENCE

Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL

(2012) Giusy Della Gatta et al.   NATURE MEDICINE

Preclinical studies of alcohol binge drinking

(2011) John C. Crabbe et al.   Annals of the New York Academy of Sciences

An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma

(2011) Pavel Sumazin et al.   CELL

Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking

(2011) Garret D. Stuber et al.   NATURE

Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked?

(2010) Markus Heilig et al.   ADDICTION BIOLOGY

Corticotropin Releasing Factor–Induced Amygdala Gamma-Aminobutyric Acid Release Plays a Key Role in Alcohol Dependence

(2010) Marisa Roberto et al.   BIOLOGICAL PSYCHIATRY

Glucocorticosteroids: current and future directions

(2010) Peter J Barnes   BRITISH JOURNAL OF PHARMACOLOGY

Ventral Tegmental Afferents in Stress-Induced Reinstatement: The Role of cAMP Response Element-Binding Protein

(2010) L. A. Briand et al.   JOURNAL OF NEUROSCIENCE

A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers

(2010) Celine Lefebvre et al.   Molecular Systems Biology

Operant Behavior and Alcohol Levels in Blood and Brain of Alcohol-Dependent Rats

(2009) Nicholas W. Gilpin et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The N-Myc-DLL3 Cascade Is Suppressed by the Ubiquitin Ligase Huwe1 to Inhibit Proliferation and Promote Neurogenesis in the Developing Brain

(2009) Xudong Zhao et al.   DEVELOPMENTAL CELL

Protracted Withdrawal from Alcohol and Drugs of Abuse Impairs Long-Term Potentiation of Intrinsic Excitability in the Juxtacapsular Bed Nucleus of the Stria Terminalis

(2009) W. Francesconi et al.   JOURNAL OF NEUROSCIENCE

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

Genome-wide identification of post-translational modulators of transcription factor activity in human B cells

(2009) Kai Wang et al.   NATURE BIOTECHNOLOGY

Neurocircuitry of Addiction

(2009) George F Koob et al.   NEUROPSYCHOPHARMACOLOGY

Differential corticosteroid receptor regulation of mesoaccumbens dopamine efflux during the peak and nadir of the circadian rhythm: A molecular equilibrium in the midbrain?

(2009) Susannah J. Tye et al.   SYNAPSE

Correlating measurements across samples improves accuracy of large-scale expression profile experiments

(2009) Mariano Alvarez et al.   GENOME BIOLOGY

Neuroplasticity in brain reward circuitry following a history of ethanol dependence

(2008) Anita C. Hansson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Morphine produces circuit-specific neuroplasticity in the bed nucleus of the stria terminalis

(2008) É.C. Dumont et al.   NEUROSCIENCE

MPZP: A novel small molecule corticotropin-releasing factor type 1 receptor (CRF1) antagonist

(2007) H RICHARDSON et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR