Distribution of circular proteins in plants: large-scale mapping of cyclotides in the Violaceae

Ixchelia, a new genus of Violaceae from Mexico and Mesoamerica

(2015) Gregory A. Wahlert et al.   BRITTONIA

The increasing value of plant-made proteins

(2015) Markus Sack et al.   CURRENT OPINION IN BIOTECHNOLOGY

A Phylogeny of the Violaceae (Malpighiales) Inferred from Plastid DNA Sequences: Implications for Generic Diversity and Intrafamilial Classification

(2014) Gregory A. Wahlert et al.   SYSTEMATIC BOTANY

Reestablishment of Calyptrion (Violaceae)

(2014) Juliana de Paula-Souza et al.   TAXON

Re-establishment of the name Pombalia, and new combinations from the polyphyletic Hybanthus (Violaceae)

(2014) Juliana De Paula-Souza et al.   Phytotaxa

Molecular Grafting onto a Stable Framework Yields Novel Cyclic Peptides for the Treatment of Multiple Sclerosis

(2013) Conan K. Wang et al.   ACS Chemical Biology

Cyclotide discovery in Gentianales revisited-identification and characterization of cyclic cystine-knot peptides and their phylogenetic distribution in Rubiaceae plants

(2013) Johannes Koehbach et al.   BIOPOLYMERS

Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design

(2013) J. Koehbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Importance of the Cell Membrane on the Mechanism of Action of Cyclotides

(2012) Sónia Troeira Henriques et al.   ACS Chemical Biology

Characterizing circular peptides in mixtures: sequence fragment assembly of cyclotides from a violet plant by MALDI-TOF/TOF mass spectrometry

(2012) Hossein Hashempour et al.   AMINO ACIDS

Orally Active Peptidic Bradykinin B1 Receptor Antagonists Engineered from a Cyclotide Scaffold for Inflammatory Pain Treatment

(2012) Clarence T. T. Wong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Circular Proteins from Plants and Fungi

(2012) Ulf Göransson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclotides Associate with Leaf Vasculature and Are the Products of a Novel Precursor inPetunia(Solanaceae)

(2012) Aaron G. Poth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Design of a Novel Cyclotide-Based CXCR4 Antagonist with Anti-Human Immunodeficiency Virus (HIV)-1 Activity

(2012) Teshome L. Aboye et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

(2012) Paul G. Arnison et al.   NATURAL PRODUCT REPORTS

A Phylogeny of Rinorea (Violaceae) Inferred from Plastid DNA Sequences with an Emphasis on the African and Malagasy Species

(2012) Gregory A. Wahlert et al.   SYSTEMATIC BOTANY

Discovery of Cyclotides in the Fabaceae Plant Family Provides New Insights into the Cyclization, Evolution, and Distribution of Circular Proteins

(2011) Aaron G. Poth et al.   ACS Chemical Biology

Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds

(2011) L. Y. Chan et al.   BLOOD

Biomedicine in the environment: Cyclotides constitute potent natural toxins in plants and soil bacteria

(2011) Rikke Gleerup Ovesen et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Clinical development of plant-produced recombinant pharmaceuticals: Vaccines, antibodies and beyond

(2011) Vidadi Yusibov et al.   Human vaccines & immunotherapeutics

Discovery and Characterization of Novel Cyclotides Originated from Chimeric Precursors Consisting of Albumin-1 Chain a and Cyclotide Domains in the Fabaceae Family

(2011) Giang Kien Truc Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytotoxic potency of small macrocyclic knot proteins: Structure–activity and mechanistic studies of native and chemically modified cyclotides

(2011) Robert Burman et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cyclotides are a component of the innate defense of Oldenlandia affinis

(2010) Joshua S. Mylne et al.   BIOPOLYMERS

Techniques for Plant Defensin Production

(2010) Lara Padovan et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria

(2010) M. Pranting et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Plant-specific glycosylation patterns in the context of therapeutic protein production

(2010) Véronique Gomord et al.   PLANT BIOTECHNOLOGY JOURNAL

Seed-based expression systems for plant molecular farming

(2010) Joseph Boothe et al.   PLANT BIOTECHNOLOGY JOURNAL

Cyclotides: macrocyclic peptides with applications in drug design and agriculture

(2009) David J. Craik et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Conserved Glu in the Cyclotide Cycloviolacin O2 Has a Key Structural Role

(2009) Ulf Göransson et al.   CHEMBIOCHEM

The Biological Activity of the Prototypic Cyclotide Kalata B1 Is Modulated by the Formation of Multimeric Pores

(2009) Yen-Hua Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circular proteins from Melicytus (Violaceae) refine the conserved protein and gene architecture of cyclotides

(2009) Manuela Trabi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cyclotide proteins and precursors from the genus Gloeospermum: Filling a blank spot in the cyclotide map of Violaceae

(2009) Robert Burman et al.   PHYTOCHEMISTRY

The Anthelmintic Activity of the Cyclotides: Natural Variants with Enhanced Activity

(2008) Michelle L. Colgrave et al.   CHEMBIOCHEM

Molecular phylogenetic analysis of Violaceae (Malpighiales) based on plastid and nuclear DNA sequences

(2008) Toru Tokuoka   JOURNAL OF PLANT RESEARCH

The fluorometric microculture cytotoxicity assay

(2008) Elin Lindhagen et al.   Nature Protocols

The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity

(2008) Anders Herrmann et al.   PHYTOCHEMISTRY

Distribution and Evolution of Circular Miniproteins in Flowering Plants

(2008) C. W. Gruber et al.   PLANT CELL

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

(2008) B. L. Barbeta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultra-Stable Peptide Scaffolds for Protein Engineering—Synthesis and Folding of the Circular Cystine Knotted Cyclotide Cycloviolacin O2

(2007) Teshome Leta Aboye et al.   CHEMBIOCHEM

Anti-HIV Cyclotides from the Chinese Medicinal HerbViola yedoensis

(2007) Conan K. L. Wang et al.   JOURNAL OF NATURAL PRODUCTS