期刊
VIRUS RESEARCH
卷 193, 期 -, 页码 130-134出版社
ELSEVIER
DOI: 10.1016/j.virusres.2014.07.002
关键词
Murine leukemia virus; Retrovirus; Fv1 restriction; APOBEC3; Tetherin
类别
资金
- Intramural Research Program of the National Institutes of Health, National Cancer Institute, Center for Cancer Research
One of the most exciting areas in contemporary retrovirus research is the discovery of restriction factors. These are cellular proteins that act after virus entry to inhibit infection by or replication of retroviruses (and other viruses and intracellular pathogens). We briefly discuss here three antiretroviral restriction factors in mice: Fv1, APOBEC3, and tetherin, touching on both biological and molecular aspects of these restriction systems. Published by Elsevier B.V.
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