TGF-beta/Smad pathway and BRAF mutation play different roles in circumscribed and infiltrative papillary thyroid carcinoma

Loss of cellular polarity/cohesiveness in the invasive front of papillary thyroid carcinoma, a novel predictor for lymph node metastasis; possible morphological indicator of epithelial mesenchymal transition

(2011) Z. Liu et al.   JOURNAL OF CLINICAL PATHOLOGY

Progression of BRAF-induced thyroid cancer is associated with epithelial–mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling

(2011) J A Knauf et al.   ONCOGENE

Intratumoural lymph vessel density is related to presence of lymph node metastases and separates encapsulated from infiltrative papillary thyroid carcinoma

(2011) C. Eloy et al.   VIRCHOWS ARCHIV

The preeminence of growth pattern and invasiveness and the limited influence of BRAF and RAS mutations in the occurrence of papillary thyroid carcinoma lymph node metastases

(2011) Catarina Eloy et al.   VIRCHOWS ARCHIV

Encapsulated Well-differentiated Follicular-patterned Thyroid Carcinomas Do Not Play a Significant Role in the Fatality Rates From Thyroid Carcinoma

(2010) Simonetta Piana et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Expression of SMAD proteins, TGF-beta/activin signaling mediators, in human thyroid tissues

(2010) Sílvia E. Matsuo et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Role of reduced expression of SMAD4 in papillary thyroid carcinoma

(2010) Sonia D'Inzeo et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Unique patterns of tumor growth related with the risk of lymph node metastasis in papillary thyroid carcinoma

(2010) Chan-Kwon Jung et al.   MODERN PATHOLOGY

Molecular genotyping of papillary thyroid carcinoma follicular variant according to its histological subtypes (encapsulated vs infiltrative) reveals distinct BRAF and RAS mutation patterns

(2010) Michael Rivera et al.   MODERN PATHOLOGY

The BRAFV600E Oncogene Induces Transforming Growth Factor   Secretion Leading to Sodium Iodide Symporter Repression and Increased Malignancy in Thyroid Cancer

(2009) G. Riesco-Eizaguirre et al.   CANCER RESEARCH

Role of Transforming Growth Factor Beta in the Regulation of Thyroid Function and Growth

(2009) Mario A. Pisarev et al.   THYROID

TGFβ in Cancer

(2008) Joan Massagué   CELL

Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer

(2008) M. Ryder et al.   ENDOCRINE-RELATED CANCER