Article
Multidisciplinary Sciences
Yingbiao Zhang, Chun-Yuan Ting, Shu Yang, John Reich, Karenne Fru, Mary A. Lilly
Summary: It is found that Wdr59 has a dual function in TORC1 regulation in different cellular contexts, promoting or inhibiting TORC1 activity.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Editorial Material
Biochemistry & Molecular Biology
Kinneret Keren
Summary: Membrane tension is suggested to connect processes along the cell's boundary mechanically. De Belly et al. demonstrate in this issue of Cell that local protrusion or contraction lead to a rapid increase in global membrane tension, while tension changes that only involve the membrane remain localized.
Article
Chemistry, Physical
Wenna Ai, Wei-Hai Fang, Neil Qiang Su
Summary: This study focuses on the range-separated correlation in long-range corrected hybrid functionals, presenting a theory on its derivation and proving its reliability and effectiveness. The new functional proposed in this work outperforms the traditional LC-BLYP method in various tests and maintains important properties of the XC potential.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Monika Janaszek-Mankowska, Arkadiusz Ratajski, Jacek Sloma
Summary: This study examined the potential of the biospeckle phenomenon for detecting fruit infestation by Drosophila suzukii. The results showed that graphical and analytical approaches were effective in evaluating biospeckle activity and identifying infested areas. The biospeckle activity index calculated from spatial-temporal speckle correlation was found to be the best indicator for distinguishing healthy fruits and fruits in different stages of infestation development.
APPLIED SCIENCES-BASEL
(2022)
Article
Cell Biology
Sourabh Bhide, Denisa Gombalova, Gregor Moenke, Johannes Stegmaier, Valentyna Zinchenko, Anna Kreshuk, Julio M. Belmonte, Maria Leptin
Summary: External mechanical stimuli are recognized as determinants of cell behavior, such as in the epithelial folding event during gastrulation in Drosophila. Some cells stretch instead of constrict, despite sharing the same genetic program. Tissue-wide interactions force these stretching cells to expand even with sufficient actomyosin, indicating a nonlinear mechanical property.
JOURNAL OF CELL BIOLOGY
(2021)
Article
Entomology
Sudan Gyawaly, Jhalendra Rijal
Summary: Spotted wing drosophila, an important invasive insect pest in the United States, is primarily controlled using synthetic insecticides, but there is a need for alternative, reduced-risk insecticides to address resistance and negative effects. Neem-based insecticides have been shown to have deterrent effects on the oviposition activities of spotted wing drosophila, reducing egg deposition by half in some cases.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2022)
Article
Engineering, Aerospace
Matthias Schulze, Jens Neumann, Thomas Klimmek
Summary: This paper investigates the influence of engine position, mass, and pylon stiffness on aeroelastic stability of a long-range wide-body transport aircraft. Models for reference and modified configurations were set up using DLR's automated design process, followed by structural optimization based on flight loads analysis. Post-analysis flutter tests showed that higher mass and engine position changes slightly increased flutter speed, with both configurations experiencing flutter at the horizontal tail-plane outside the stability envelope.
Article
Multidisciplinary Sciences
Kathleen K. A. Cho, Jingcheng Shi, Aarron J. Phensy, Marc L. Turner, Vikaas S. Sohal
Summary: Changes in activity patterns in the medial prefrontal cortex allow animals and humans to adapt their behavior to changes in the environment, such as during cognitive tasks. Parvalbumin-expressing inhibitory neurons play a role in learning new strategies during rule-shift tasks, but the circuit interactions involved in switching prefrontal network dynamics remain unknown.
Article
Genetics & Heredity
Markus Togel, Guenther Pass, Achim Paululat
Summary: The development of wings in fruit flies depends on the activity of wing hearts, which are crucial accessory circulatory organs. Mutant flies lacking intact wing hearts exhibit impaired flight and malformed wings. In mutant flies where the third thoracic segment is transformed into a second thoracic segment, a second pair of functional wings and wing hearts are formed.
Article
Environmental Studies
Swapnil S. Jagtap, Peter R. N. Childs, Marc E. J. Stettler
Summary: Decarbonising long-range aviation is challenging. This study evaluates the performance of six low-carbon fuels and their realistic impacts on aircraft design for a large long-range passenger aircraft using Breguet's range equation. Liquid hydrogen (LH2) and 100 % synthetic paraffin kerosene (SPK) are the only two alternative fuels found to be viable. Our results should inform studies on LH2 and 100 % SPK aircraft operating costs and lifecycle emissions.
TRANSPORTATION RESEARCH PART D-TRANSPORT AND ENVIRONMENT
(2023)
Article
Developmental Biology
Tanvi Gore, Tamas Matusek, Gisela D'Angelo, Cecile Giordano, Thomas Tognacci, Laurence Lavenant-Staccini, Catherine Rabouille, Pascal P. Therond
Summary: Depletion of Rab8 in Hh-producing cells disrupts the balance between apical and lateral release of Hh, leading to differential effects on the expression of Hh target genes. Rab8 is also involved in regulating the endocytosis and apico-basal distribution of Ihog, which is crucial for establishing the Hh gradient. This study provides new insights into how morphogen activity is distributed between apical and basolaterally secreted pools.
Article
Multidisciplinary Sciences
Sandra M. Ritchie, Sasa Kovacevic, Prithviraj Deshmukh, Alexander D. Christodoulides, Jonathan A. Malen, Sinisa Dj. Mesarovic, Rahul P. Panat
Summary: This paper investigates the causes and mechanisms of distortion during sintering and develops a continuum model to describe and control this phenomenon.
NATURE COMMUNICATIONS
(2023)
Article
Biology
Marion Hoareau, Juliette de Noiron, Jessie Colin, Isabelle Guenal
Summary: This paper presents a simple method for mass purification of Drosophila melanogaster larval tissues. The protocol allows researchers to preserve tissue integrity, is achievable by individual researchers, and allows simultaneous purification of different samples.
Article
Engineering, Aerospace
Stanislav Karpuk, Yiyuan Ma, Ali Elham
Summary: This study investigates the potential of a commercial blended wing body configuration powered by hydrogen combustion engines with future technologies. Results show a potential reduction in equivalent CO2 emissions compared to kerosene and conventional aircraft. Advancements in future technologies, such as boundary layer ingestion and ultra-high bypass ratio engines, significantly affect the aircraft's geometric layout and fuel reduction potential. However, the operating costs of hydrogen aircraft may be a significant challenge if pessimistic hydrogen prices are achieved. Additionally, the volume requirements for storing hydrogen fuel pose configurational problems.
Article
Neurosciences
Alex T. L. Leong, Xunda Wang, Eddie C. Wong, Celia M. Dong, Ed X. Wu
Summary: The study uncovered the propagation pathways of neural signals in the brain using optogenetics and functional MRI, showing that such propagation can modulate sensory functions. The research indicated that the temporal characteristics of neural activity play a crucial role in determining the pathways of neural signal propagation.
Review
Genetics & Heredity
Rosalind Hale, David Strutt
ANNUAL REVIEW OF GENETICS, VOL 49
(2015)
Editorial Material
Biochemistry & Molecular Biology
Helen Strutt, David Strutt
Article
Cell Biology
Helen Strutt, Jessica Gamage, David Strutt
Article
Biology
Pedro Saavedra, Amy Brittle, Isabel M. Palacios, David Strutt, Jose Casal, Peter A. Lawrence
Article
Biochemistry & Molecular Biology
Helen Strutt, Paul F. Langton, Neil Pearson, Kirsty J. McMillan, David Strutt, Peter J. Cullen
Article
Cell Biology
Margarida Ressurreicao, Samantha Warrington, David Strutt
Article
Developmental Biology
Katherine H. Fisher, David Strutt
Article
Biology
Helen Strutt, Jessica Gamage, David Strutt
Article
Developmental Biology
Varun Chaudhary, Swapnil Hingole, Jana Frei, Fillip Port, David Strutt, Michael Boutros
Article
Biochemistry & Molecular Biology
Andreas Gerondopoulos, Helen Strutt, Nicola L. Stevenson, Tomoaki Sobajima, Tim P. Levine, David J. Stephens, David Strutt, Francis A. Barr
Review
Biochemistry & Molecular Biology
Carl Harrison, Hongyu Shao, Helen Strutt, David Strutt
BIOCHEMICAL SOCIETY TRANSACTIONS
(2020)
Article
Developmental Biology
Su Ee Tan, Weijie Tan, Katherine H. Fisher, David Strutt
Summary: The study introduced a novel planar polarity quantification method based on PCA, which is insensitive to cell geometry variation. Comparison with other methods revealed that the PCA method robustly quantifies planar polarity. A user-friendly interface called QuantifyPolarity was designed for automated polarity, morphology, and geometry analysis.
Article
Cell Biology
Amy Brittle, Samantha J. Warrington, Helen Strutt, Elizabeth Manning, Su Ee Tan, David Strutt
Summary: This study investigates the roles of the core and Fat-Dachsous pathways in planar polarity establishment during Drosophila pupal wing development, revealing that the core pathway functions through strong feedback for self-organizing cell polarity, while the Ft-Ds pathway relies on strong global cues and weak feedback mechanisms for amplifying cell polarity.
Article
Multidisciplinary Sciences
Katherine H. Fisher, David Strutt, Alexander G. Fletcher
Article
Biochemistry & Molecular Biology
Samantha J. Warrington, Helen Strutt, Katherine H. Fisher, David Strutt