ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation

Crystal structures of a double-barrelled fluoride ion channel

(2015) Randy B. Stockbridge et al.   NATURE

Architecture of the synaptotagmin–SNARE machinery for neuronal exocytosis

(2015) Qiangjun Zhou et al.   NATURE

Fusion-protein-assisted protein crystallization

(2015) Bostjan Kobe et al.   Acta Crystallographica Section F-Structural Biology Communications

A Structural Portrait of the PDZ Domain Family

(2014) Andreas Ernst et al.   JOURNAL OF MOLECULAR BIOLOGY

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

PRDM14: a unique regulator for pluripotency and epigenetic reprogramming

(2014) Fumio Nakaki et al.   TRENDS IN BIOCHEMICAL SCIENCES

PRDM14 Ensures Naive Pluripotency through Dual Regulation of Signaling and Epigenetic Pathways in Mouse Embryonic Stem Cells

(2013) Masashi Yamaji et al.   Cell Stem Cell

How to make a primordial germ cell

(2013) E. Magnusdottir et al.   DEVELOPMENT

PRDM14 promotes active DNA demethylation through the Ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells

(2013) N. Okashita et al.   DEVELOPMENT

A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL)

(2013) B. L. Carofino et al.   Disease Models & Mechanisms

Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation

(2013) Nils Grabole et al.   EMBO REPORTS

High expression of PRDM14 correlates with cell differentiation and is a novel prognostic marker in resected non-small cell lung cancer

(2013) Tiehong Zhang et al.   MEDICAL ONCOLOGY

Tsix RNA and the Germline Factor, PRDM14, Link X Reactivation and Stem Cell Reprogramming

(2013) Bernhard Payer et al.   MOLECULAR CELL

Induction of mouse germ-cell fate by transcription factors in vitro

(2013) Fumio Nakaki et al.   NATURE

A tripartite transcription factor network regulates primordial germ cell specification in mice

(2013) Erna Magnúsdóttir et al.   NATURE CELL BIOLOGY

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14

(2013) Elise Ruark et al.   NATURE GENETICS

Naive pluripotency is associated with global DNA hypomethylation

(2013) Harry G Leitch et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains

(2013) F. Sha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zscan4 restores the developmental potency of embryonic stem cells

(2013) Tomokazu Amano et al.   Nature Communications

Roles for Tbx3 in regulation of two-cell state and telomere elongation in mouse ES cells

(2013) Jiameng Dan et al.   Scientific Reports

Single-Cell Profiling of Epigenetic Modifiers Identifies PRDM14 as an Inducer of Cell Fate in the Mammalian Embryo

(2013) Adam Burton et al.   Cell Reports

Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of PRDM9

(2013) Hong Wu et al.   Cell Reports

Synergistic Mechanisms of DNA Demethylation during Transition to Ground-State Pluripotency

(2013) Jamie A. Hackett et al.   Stem Cell Reports

Structural insights for engineering binding proteins based on non-antibody scaffolds

(2012) Ryan N Gilbreth et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Prdm family: expanding roles in stem cells and development

(2012) T. Hohenauer et al.   DEVELOPMENT

Broad Ranges of Affinity and Specificity of Anti-Histone Antibodies Revealed by a Quantitative Peptide Immunoprecipitation Assay

(2012) Shingo Nishikori et al.   JOURNAL OF MOLECULAR BIOLOGY

Embryonic stem cell potency fluctuates with endogenous retrovirus activity

(2012) Todd S. Macfarlan et al.   NATURE

Linkers in the structural biology of protein-protein interactions

(2012) Vishnu Priyanka Reddy Chichili et al.   PROTEIN SCIENCE

A PRC2-Dependent Repressive Role of PRDM14 in Human Embryonic Stem Cells and Induced Pluripotent Stem Cell Reprogramming

(2012) Yun-Shen Chan et al.   STEM CELLS

AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches

(2012) Megan A. Hatlen et al.   Frontiers of Medicine

PRDM proteins: Important players in differentiation and disease

(2011) Cathrine K. Fog et al.   BIOESSAYS

Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis

(2011) Florian Grebien et al.   CELL

Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells

(2011) Katsuhiko Hayashi et al.   CELL

Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells

(2011) M. Saitou et al.   DEVELOPMENT

Substrate and product specificities of SET domain methyltransferases

(2011) Paul A. Del Rizzo et al.   Epigenetics

Teaching an Old Scaffold New Tricks: Monobodies Constructed Using Alternative Surfaces of the FN3 Scaffold

(2011) Akiko Koide et al.   JOURNAL OF MOLECULAR BIOLOGY

Prdm14 initiates lymphoblastic leukemia after expanding a population of cells resembling common lymphoid progenitors

(2011) E J Dettman et al.   ONCOGENE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

Nucleosome dynamics define transcriptional enhancers

(2010) Housheng Hansen He et al.   NATURE GENETICS

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain

(2010) John Wojcik et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates

(2010) Ziyang Ma et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Decision-making in structure solution using Bayesian estimates of map quality: thePHENIX AutoSolwizard

(2009) Thomas C. Terwilliger et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity

(2009) S. Park et al.   BLOOD

Jarid2/Jumonji Coordinates Control of PRC2 Enzymatic Activity and Target Gene Occupancy in Pluripotent Cells

(2009) Jamy C. Peng et al.   CELL

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

Engineering of recombinant crystallization chaperones

(2009) Shohei Koide   CURRENT OPINION IN STRUCTURAL BIOLOGY

Chemical mechanisms of histone lysine and arginine modifications

(2008) Brian C. Smith et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Novel RNA-binding properties of the MTG chromatin regulatory proteins

(2008) Stefano Rossetti et al.   BMC MOLECULAR BIOLOGY

A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein–Protein Interfaces

(2008) Ryan N. Gilbreth et al.   JOURNAL OF MOLECULAR BIOLOGY

Critical function of Prdm14 for the establishment of the germ cell lineage in mice

(2008) Masashi Yamaji et al.   NATURE GENETICS