GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function
出版年份 2015 全文链接
标题
GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function
作者
关键词
-
出版物
eLife
Volume 4, Issue -, Pages -
出版商
eLife Sciences Organisation, Ltd.
发表日期
2015-12-10
DOI
10.7554/elife.08881
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Nuclear accumulation of mRNAs underlies G4C2-repeat-induced translational repression in a cellular model of C9orf72 ALS
- (2015) S. Rossi et al. JOURNAL OF CELL SCIENCE
- Fragile X mental retardation protein interactions with a G quadruplex structure in the 3′-untranslated region of NR2B mRNA
- (2015) Snezana Stefanovic et al. Molecular BioSystems
- The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
- (2015) Ke Zhang et al. NATURE
- GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
- (2015) Brian D. Freibaum et al. NATURE
- Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
- (2015) Ana Jovičić et al. NATURE NEUROSCIENCE
- Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS
- (2015) Helene Tran et al. NEURON
- C9orf72 nucleotide repeat structures initiate molecular cascades of disease
- (2014) Aaron R. Haeusler et al. NATURE
- Combating neurodegenerative disease with chemical probes and model systems
- (2014) Priyanka Narayan et al. Nature Chemical Biology
- A census of human RNA-binding proteins
- (2014) Stefanie Gerstberger et al. NATURE REVIEWS GENETICS
- Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
- (2014) Nael H. Alami et al. NEURON
- Identification of STAT5A and STAT5B Target Genes in Human T Cells
- (2014) Takahiro Kanai et al. PLoS One
- C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins
- (2014) S. Mizielinska et al. SCIENCE
- Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells
- (2014) I. Kwon et al. SCIENCE
- Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
- (2013) Sandra Almeida et al. ACTA NEUROPATHOLOGICA
- The Disease-associated r(GGGGCC)nRepeat from theC9orf72Gene Forms Tract Length-dependent Uni- and Multimolecular RNA G-quadruplex Structures
- (2013) Kaalak Reddy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Central Dogma Decentralized: New Perspectives on RNA Function and Local Translation in Neurons
- (2013) Christine E. Holt et al. NEURON
- Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
- (2013) Peter E.A. Ash et al. NEURON
- RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
- (2013) Christopher J. Donnelly et al. NEURON
- The Unstable Repeats—Three Evolving Faces of Neurological Disease
- (2013) David L. Nelson et al. NEURON
- TDP-43 pathology in polyglutamine diseases: With reference to amyotrphic lateral sclerosis
- (2013) Yasuko Toyoshima et al. NEUROPATHOLOGY
- Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration
- (2013) Z. Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
- (2013) K. Mori et al. SCIENCE
- Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95
- (2012) Nien-Pei Tsai et al. CELL
- A Pan-European Study of theC9orf72Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats
- (2012) Julie van der Zee et al. HUMAN MUTATION
- RNA-mediated toxicity in neurodegenerative disease
- (2012) Veronique V. Belzil et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Modulation of dendritic AMPA receptor mRNA trafficking by RNA splicing and editing
- (2012) Luca La Via et al. NUCLEIC ACIDS RESEARCH
- PolyQ disease: misfiring of a developmental cell death program?
- (2012) Elyse S. Blum et al. TRENDS IN CELL BIOLOGY
- Cytoplasmic RNA-Binding Proteins and the Control of Complex Brain Function
- (2012) J. C. Darnell et al. Cold Spring Harbor Perspectives in Biology
- C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes
- (2012) Pietro Fratta et al. Scientific Reports
- FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
- (2011) Jennifer C. Darnell et al. CELL
- G–quadruplex RNA structure as a signal for neurite mRNA targeting
- (2011) Murugan Subramanian et al. EMBO REPORTS
- Cellular toxicity of expanded RNA repeats: focus on RNA foci
- (2011) Marzena Wojciechowska et al. HUMAN MOLECULAR GENETICS
- A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study
- (2011) Ilse Gijselinck et al. LANCET NEUROLOGY
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
- (2010) Andrew C. Elden et al. NATURE
- Spatiotemporal expression of PSD-95 in Fmr1 knockout mice brain
- (2010) Zhi-Wei Zhu et al. NEUROPATHOLOGY
- A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons
- (2010) Shu-Chun Peng et al. NUCLEIC ACIDS RESEARCH
- Drosophila Orb2 targets genes involved in neuronal growth, synapse formation, and protein turnover
- (2010) T. Mastushita-Sakai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non-ATG-initiated translation directed by microsatellite expansions
- (2010) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mRNA Localization: Gene Expression in the Spatial Dimension
- (2009) Kelsey C. Martin et al. CELL
- Egalitarian is a selective RNA-binding protein linking mRNA localization signals to the dynein motor
- (2009) M. Dienstbier et al. GENES & DEVELOPMENT
- Genetic Modifiers of dFMR1 Encode RNA Granule Components in Drosophila
- (2009) Anne-Marie J. Cziko et al. GENETICS
- The FXG: A Presynaptic Fragile X Granule Expressed in a Subset of Developing Brain Circuits
- (2009) S. B. Christie et al. JOURNAL OF NEUROSCIENCE
- m-TAG: a PCR-based genomic integration method to visualize the localization of specific endogenous mRNAs in vivo in yeast
- (2009) Liora Haim-Vilmovsky et al. Nature Protocols
- A Direct Role for FMRP in Activity-Dependent Dendritic mRNA Transport Links Filopodial-Spine Morphogenesis to Fragile X Syndrome
- (2008) Jason B. Dictenberg et al. DEVELOPMENTAL CELL
- RNA toxicity is a component of ataxin-3 degeneration in Drosophila
- (2008) Ling-Bo Li et al. NATURE
- Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes
- (2008) Daisuke Satoh et al. NATURE CELL BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started