The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin

Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis

(2015) R. Micanovic et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Colon-Specific Deletion of Epithelial Sodium Channel Causes Sodium Loss and Aldosterone Resistance

(2014) S. Malsure et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Common Variants in UMOD Associate with Urinary Uromodulin Levels: A Meta-Analysis

(2014) M. Olden et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Role of hepsin in factor VII activation in zebrafish

(2013) Gauri Khandekar et al.   BLOOD CELLS MOLECULES AND DISEASES

Three deaf mice: mouse models for TECTA-based human hereditary deafness reveal domain-specific structural phenotypes in the tectorial membrane

(2013) P. K. Legan et al.   HUMAN MOLECULAR GENETICS

Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension

(2013) Caroline Ronzaud et al.   JOURNAL OF CLINICAL INVESTIGATION

Calcium signaling-related proteins are associated with broncho-pulmonary dysplasia progression

(2013) Cinzia Magagnotti et al.   Journal of Proteomics

Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression

(2013) Matteo Trudu et al.   NATURE MEDICINE

A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing

(2013) Bob Glaudemans et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in mice

(2012) Yu-Chen Hsu et al.   HEPATOLOGY

Uromodulin Triggers IL-1 -Dependent Innate Immunity via the NLRP3 Inflammasome

(2012) M. N. Darisipudi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Urinary secretion and extracellular aggregation of mutant uromodulin isoforms

(2012) Céline Schaeffer et al.   KIDNEY INTERNATIONAL

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Activation of the Bumetanide-sensitive Na+,K+,2Cl−Cotransporter (NKCC2) Is Facilitated by Tamm-Horsfall Protein in a Chloride-sensitive Manner

(2011) Kerim Mutig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The rediscovery of uromodulin (Tamm–Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease

(2011) Luca Rampoldi et al.   KIDNEY INTERNATIONAL

Proteolytic Activation of Pro-Macrophage-Stimulating Protein by Hepsin

(2011) R. Ganesan et al.   MOLECULAR CANCER RESEARCH

Insights into Egg Coat Assembly and Egg-Sperm Interaction from the X-Ray Structure of Full-Length ZP3

(2010) Ling Han et al.   CELL

Establishment of an in vivo model facilitates B2 receptor protein maturation and heterodimerization

(2010) Joshua Abd Alla et al.   Integrative Biology

Tamm-Horsfall Glycoprotein Interacts with Renal Outer Medullary Potassium Channel ROMK2 and Regulates Its Function

(2010) Aparna Renigunta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MOF and Histone H4 Acetylation at Lysine 16 Are Critical for DNA Damage Response and Double-Strand Break Repair

(2010) G. G. Sharma et al.   MOLECULAR AND CELLULAR BIOLOGY

Atlas of gene expression in the mouse kidney: new features of glomerular parietal cells

(2010) Lydie Cheval et al.   PHYSIOLOGICAL GENOMICS

Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension

(2010) Sandosh Padmanabhan et al.   PLoS Genetics

Calreticulin enhances B2 bradykinin receptor maturation and heterodimerization

(2009) Joshua Abd Alla et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA

(2009) Kate A. Owen et al.   BIOCHEMICAL JOURNAL

Probing the substrate specificities of matriptase, matriptase-2, hepsin and DESC1 with internally quenched fluorescent peptides

(2009) François Béliveau et al.   FEBS Journal

Hepsin activates prostasin and cleaves the extracellular domain of the epidermal growth factor receptor

(2009) Mengqian Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Multiple loci associated with indices of renal function and chronic kidney disease

(2009) Anna Köttgen et al.   NATURE GENETICS

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

(2009) Eric Campeau et al.   PLoS One

Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct

(2009) M.-J. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Urinary uromodulin carries an intact ZP domain generated by a conserved C-terminal proteolytic cleavage

(2008) Sara Santambrogio et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Analysis of Uromodulin Polymerization Provides New Insights into the Mechanisms Regulating ZP Domain-mediated Protein Assembly

(2008) Céline Schaeffer et al.   MOLECULAR BIOLOGY OF THE CELL

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice

(2008) Milena Traykova-Brauch et al.   NATURE MEDICINE