Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy

Contractile dysfunction in muscle may underlie androgen-dependent motor dysfunction in spinal bulbar muscular atrophy

(2015) Kentaro Oki et al.   JOURNAL OF APPLIED PHYSIOLOGY

Protein Arginine Methyltransferase 6 Enhances Polyglutamine-Expanded Androgen Receptor Function and Toxicity in Spinal and Bulbar Muscular Atrophy

(2015) Chiara Scaramuzzino et al.   NEURON

Muscle Expression of Mutant Androgen Receptor Accounts for Systemic and Motor Neuron Disease Phenotypes in Spinal and Bulbar Muscular Atrophy

(2014) Constanza J. Cortes et al.   NEURON

Peripheral Androgen Receptor Gene Suppression Rescues Disease in Mouse Models of Spinal and Bulbar Muscular Atrophy

(2014) Andrew P. Lieberman et al.   Cell Reports

Androgen-dependent impairment of myogenesis in spinal and bulbar muscular atrophy

(2013) Adriana Malena et al.   ACTA NEUROPATHOLOGICA

Ube3a/E6AP is involved in a subset of MeCP2 functions

(2013) Soeun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Polyglutamine Disease Toxicity Is Regulated by Nemo-like Kinase in Spinocerebellar Ataxia Type 1

(2013) H. Ju et al.   JOURNAL OF NEUROSCIENCE

Aggregation formation in the polyglutamine diseases: Protection at a cost?

(2013) Tiffany W. Todd et al.   MOLECULES AND CELLS

More than a bystander: the contributions of intrinsic skeletal muscle defects in motor neuron diseases

(2013) Justin G. Boyer et al.   Frontiers in Physiology

Nemo-like kinase, a multifaceted cell signaling regulator

(2012) Tohru Ishitani et al.   CELLULAR SIGNALLING

An open trial of long-term testosterone suppression in spinal and bulbar muscular atrophy

(2012) Tomotaka Yamamoto et al.   MUSCLE & NERVE

Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract

(2012) Makoto Minamiyama et al.   NATURE MEDICINE

Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA)

(2012) Masahisa Katsuno et al.   PROGRESS IN NEUROBIOLOGY

SIRT1 Modulates Aggregation and Toxicity through Deacetylation of the Androgen Receptor in Cell Models of SBMA

(2011) H. L. Montie et al.   JOURNAL OF NEUROSCIENCE

Efficacy and safety of dutasteride in patients with spinal and bulbar muscular atrophy: a randomised placebo-controlled trial

(2011) Lindsay E Fernández-Rhodes et al.   LANCET NEUROLOGY

Transcriptional Synergy between Melanoma Antigen Gene Protein-A11 (MAGE-11) and p300 in Androgen Receptor Signaling

(2010) Emily B. Askew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Interdomain Interaction of the Androgen Receptor Is Required for Its Aggregation and Toxicity in Spinal and Bulbar Muscular Atrophy

(2010) Christopher R. Orr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disrupted Transforming Growth Factor-  Signaling in Spinal and Bulbar Muscular Atrophy

(2010) M. Katsuno et al.   JOURNAL OF NEUROSCIENCE

Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial

(2010) Masahisa Katsuno et al.   LANCET NEUROLOGY

Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex

(2010) Tohru Ishitani et al.   NATURE CELL BIOLOGY

Native Functions of the Androgen Receptor Are Essential to Pathogenesis in a Drosophila Model of Spinobulbar Muscular Atrophy

(2010) Natalia B. Nedelsky et al.   NEURON

Microarray Analysis of Gene Expression by Skeletal Muscle of Three Mouse Models of Kennedy Disease/Spinal Bulbar Muscular Atrophy

(2010) Kaiguo Mo et al.   PLoS One

Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy

(2009) Haruhiko Banno et al.   ANNALS OF NEUROLOGY

Clinical features of spinal and bulbar muscular atrophy

(2009) Lindsay E. Rhodes et al.   BRAIN

Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy

(2009) Heather L. Montie et al.   HUMAN MOLECULAR GENETICS

Molecular cell biology of androgen receptor signalling

(2009) Nigel C. Bennett et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Melanoma Antigen Gene Protein-A11 (MAGE-11) F-box Links the Androgen Receptor NH2-terminal Transactivation Domain to p160 Coactivators

(2009) Emily B. Askew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serum creatine kinase levels in spinobulbar muscular atrophy and amyotrophic lateral sclerosis

(2009) Nizar Chahin et al.   MUSCLE & NERVE

Overexpression of IGF-1 in Muscle Attenuates Disease in a Mouse Model of Spinal and Bulbar Muscular Atrophy

(2009) Isabella Palazzolo et al.   NEURON

Aberrant E2F activation by polyglutamine expansion of androgen receptor in SBMA neurotoxicity

(2009) E. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nemo-like kinase induces apoptosis and inhibits androgen receptor signaling in prostate cancer cells

(2009) Katayoon H. Emami et al.   PROSTATE

Spinal and bulbar muscular atrophy: a motoneuron or muscle disease?

(2008) C JORDAN et al.   CURRENT OPINION IN PHARMACOLOGY

Androgen receptor and Kennedy disease/spinal bulbar muscular atrophy

(2008) Douglas Ashley Monks et al.   HORMONES AND BEHAVIOR

Mitochondrial abnormalities in spinal and bulbar muscular atrophy

(2008) Srikanth Ranganathan et al.   HUMAN MOLECULAR GENETICS

Spinal and bulbar muscular atrophy: Skeletal muscle pathology in male patients and heterozygous females

(2007) Gianni Sorarù et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES