The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing

A Short Splice Form of Xin-Actin Binding Repeat Containing 2 (XIRP2) Lacking the Xin Repeats Is Required for Maintenance of Stereocilia Morphology and Hearing Function

(2015) S. P. Francis et al.   JOURNAL OF NEUROSCIENCE

Assembly of hair bundles, an amazing problem for cell biology

(2015) Peter-G. Barr-Gillespie   MOLECULAR BIOLOGY OF THE CELL

Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear

(2015) Meghan C. Drummond et al.   Nature Communications

Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins

(2015) Praveena Narayanan et al.   Nature Communications

SHIELD: an integrative gene expression database for inner ear research

(2015) Jun Shen et al.   Database-The Journal of Biological Databases and Curation

XIRP2, an Actin-Binding Protein Essential for Inner Ear Hair-Cell Stereocilia

(2015) Déborah I. Scheffer et al.   Cell Reports

Absence of plastin 1 causes abnormal maintenance of hair cell stereocilia and a moderate form of hearing loss in mice

(2014) Ruth Taylor et al.   HUMAN MOLECULAR GENETICS

Chaperone-enhanced purification of unconventional myosin 15, a molecular motor specialized for stereocilia protein trafficking

(2014) J. E. Bird et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Actin and Fascin-2 Cooperate to Maintain Stereocilia Length

(2013) B. J. Perrin et al.   JOURNAL OF NEUROSCIENCE

Molecular architecture of the chick vestibular hair bundle

(2013) Jung-Bum Shin et al.   NATURE NEUROSCIENCE

Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2

(2013) David N. Furness et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Screening forMYO15Agene mutations in autosomal recessive nonsyndromic,GJB2negative Iranian deaf population

(2012) Zohreh Fattahi et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

TMHS Is an Integral Component of the Mechanotransduction Machinery of Cochlear Hair Cells

(2012) Wei Xiong et al.   CELL

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia

(2012) Duan-Sun Zhang et al.   NATURE

Use the force: membrane tension as an organizer of cell shape and motility

(2012) Alba Diz-Muñoz et al.   TRENDS IN CELL BIOLOGY

Principles of Unconventional Myosin Function and Targeting

(2011) M. Amanda Hartman et al.   Annual Review of Cell and Developmental Biology

Regulation of Stereocilia Length by Myosin XVa and Whirlin Depends on the Actin-Regulatory Protein Eps8

(2011) Uri Manor et al.   CURRENT BIOLOGY

Prioritized sequencing of the second exon of MYO15A reveals a new mutation segregating in a Pakistani family with moderate to severe hearing loss

(2011) Rasheeda Bashir et al.   European Journal of Medical Genetics

Actin in hair cells and hearing loss

(2011) Meghan C. Drummond et al.   HEARING RESEARCH

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes

(2011) Yoshiyuki Kawashima et al.   JOURNAL OF CLINICAL INVESTIGATION

Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia

(2011) E. Caberlotto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction

(2011) Anthony W. Peng et al.   Nature Communications

Eps8 Regulates Hair Bundle Length and Functional Maturation of Mammalian Auditory Hair Cells

(2011) Valeria Zampini et al.   PLOS BIOLOGY

Actin-Bundling Protein TRIOBP Forms Resilient Rootlets of Hair Cell Stereocilia Essential for Hearing

(2010) Shin-ichiro Kitajiri et al.   CELL

Recurrent and Private MYO15A Mutations Are Associated with Deafness in the Turkish Population

(2010) F. Basak Cengiz et al.   Genetic Testing and Molecular Biomarkers

The cell biology of hearing

(2010) Martin Schwander et al.   JOURNAL OF CELL BIOLOGY

Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-β2 and RanGTP

(2010) John F. Dishinger et al.   NATURE CELL BIOLOGY

A Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution

(2010) Q. Hu et al.   SCIENCE

Fast Adaptation and Ca2+ Sensitivity of the Mechanotransducer Require Myosin-XVa in Inner But Not Outer Cochlear Hair Cells

(2009) R. Stepanyan et al.   JOURNAL OF NEUROSCIENCE

Localization of inner hair cell mechanotransducer channels using high-speed calcium imaging

(2009) Maryline Beurg et al.   NATURE NEUROSCIENCE

Unconventional myosin traffic in cells reveals a selective actin cytoskeleton

(2009) C. M. Brawley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic length regulation of sensory stereocilia

(2008) U MANOR et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY