Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality

Ageing and inflammation – A central role for mitochondria in brain health and disease

(2015) Antonio Currais   AGEING RESEARCH REVIEWS

Atypical antidepressants extend lifespan ofCaenorhabditis elegansby activation of a non-cell-autonomous stress response

(2015) Sunitha Rangaraju et al.   AGING CELL

Gene expression defines natural changes in mammalian lifespan

(2015) Alexey A. Fushan et al.   AGING CELL

Accelerated epigenetic aging in Down syndrome

(2015) Steve Horvath et al.   AGING CELL

The Biology of Proteostasis in Aging and Disease

(2015) Johnathan Labbadia et al.   Annual Review of Biochemistry

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

(2015) Dirk M. Walther et al.   CELL

Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal

(2015) Kristopher Burkewitz et al.   CELL

Neuronal Serotonin Release Triggers the Heat Shock Response in C. elegans in the Absence of Temperature Increase

(2015) Marcus C. Tatum et al.   CURRENT BIOLOGY

Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span

(2015) Mintie Pu et al.   GENES & DEVELOPMENT

H3K36 methylation promotes longevity by enhancing transcriptional fidelity

(2015) Payel Sen et al.   GENES & DEVELOPMENT

Measuring Food Intake and Nutrient Absorption in Caenorhabditis elegans

(2015) Rafael L. Gomez-Amaro et al.   GENETICS

Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction

(2015) Johnathan Labbadia et al.   MOLECULAR CELL

Deciphering death: a commentary on Gompertz (1825) 'On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies'

(2015) T. B. L. Kirkwood   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Uncoupling lifespan and healthspan inCaenorhabditis eleganslongevity mutants

(2015) Ankita Bansal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetric Transcript Discovery by RNA-seq in C. elegans Blastomeres Identifies neg-1, a Gene Important for Anterior Morphogenesis

(2015) Erin Osborne Nishimura et al.   PLoS Genetics

Measuring Food Intake and Nutrient Absorption in Caenorhabditis elegans

(2015) Rafael L. Gomez-Amaro et al.   GENETICS

Visualizing samples with box plots

(2014) Martin Krzywinski et al.   NATURE METHODS

Systemic stress signalling: understanding the cell non-autonomous control of proteostasis

(2014) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Isolation of Specific Neurons from C. elegans Larvae for Gene Expression Profiling

(2014) W. Clay Spencer et al.   PLoS One

Life spanning murine gene expression profiles in relation to chronological and pathological aging in multiple organs

(2013) Martijs J. Jonker et al.   AGING CELL

Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile

(2013) Evi M. Mercken et al.   AGING CELL

Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes

(2013) Mohammed Mahidur Rahman et al.   AGING CELL

A pharmacological network for lifespan extension inCaenorhabditis elegans

(2013) Xiaolan Ye et al.   AGING CELL

Mitonuclear protein imbalance as a conserved longevity mechanism

(2013) Riekelt H. Houtkooper et al.   NATURE

The origin of aging: imperfectness-driven non-random damage defines the aging process and control of lifespan

(2013) Vadim N. Gladyshev   TRENDS IN GENETICS

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

DNA damage, chromatin, and transcription: the trinity of aging

(2012) Rebecca C Burgess et al.   CURRENT OPINION IN CELL BIOLOGY

RPN-6 determines C. elegans longevity under proteotoxic stress conditions

(2012) David Vilchez et al.   NATURE

Detecting Differential Expression in RNA-sequence Data Using Quasi-likelihood with Shrunken Dispersion Estimates

(2012) Steven P. Lund et al.   Statistical Applications in Genetics and Molecular Biology

Early cohort mortality predicts the rate of aging in the cohort: a historical analysis

(2012) H. Beltrán-Sánchez et al.   Journal of Developmental Origins of Health and Disease

The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner

(2011) Travis J. Maures et al.   AGING CELL

Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

(2011) Guang-Hui Liu et al.   NATURE

Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan

(2011) Silvestre Alavez et al.   NATURE

Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans

(2011) Eric L. Greer et al.   NATURE

New insights into oncogenic stress

(2011) Kevin M Haigis et al.   NATURE GENETICS

Aging as an Event of Proteostasis Collapse

(2011) R. C. Taylor et al.   Cold Spring Harbor Perspectives in Biology

MicroRNA Predictors of Longevity in Caenorhabditis elegans

(2011) Zachary Pincus et al.   PLoS Genetics

Measuring Caenorhabditis elegans Life Span in 96 Well Microtiter Plates

(2011) Gregory M. Solis et al.   Jove-Journal of Visualized Experiments

Effects of Oxidative Stress on Behavior, Physiology, and the Redox Thiol Proteome of Caenorhabditis elegans

(2010) Caroline Kumsta et al.   ANTIOXIDANTS & REDOX SIGNALING

Elevated Histone Expression Promotes Life Span Extension

(2010) Jason Feser et al.   MOLECULAR CELL

Biodemography of human ageing

(2010) James W. Vaupel   NATURE

Neural mechanisms of ageing and cognitive decline

(2010) Nicholas A. Bishop et al.   NATURE

Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

(2010) Brian Onken et al.   PLoS One

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans

(2010) Della C. David et al.   PLOS BIOLOGY

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Condition-adapted stress and longevity gene regulation byCaenorhabditis elegansSKN-1/Nrf

(2009) Riva P. Oliveira et al.   AGING CELL

Meta-analysis of age-related gene expression profiles identifies common signatures of aging

(2009) João Pedro de Magalhães et al.   BIOINFORMATICS

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

The HIF-1 Hypoxia-Inducible Factor Modulates Lifespan in C. elegans

(2009) Yi Zhang et al.   PLoS One

Aging Mice Show a Decreasing Correlation of Gene Expression within Genetic Modules

(2009) Lucinda K. Southworth et al.   PLoS Genetics

Valproic acid extends Caenorhabditis elegans lifespan

(2008) Kimberley Evason et al.   AGING CELL

An elt-3/elt-5/elt-6 GATA Transcription Circuit Guides Aging in C. elegans

(2008) Yelena V. Budovskaya et al.   CELL

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE