Review
Parasitology
Qing Liu, Xianyong Liu, Xiaomin Zhao, Xing-Quan Zhu, Xun Suo
Summary: This review evaluates the advantages and limitations of attenuation methods and attenuated Eimeria strains, and summarizes recent advances in transient/stable transfection systems and CRISPR-based genome editing for Eimeria parasites. It also discusses the trends and challenges in developing live attenuated anticoccidial vaccines based on transgenesis and genome editing.
TRENDS IN PARASITOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Carolina Trujillo-Peralta, Aaron Ashcraft, Roberto Senas-Cuesta, Makenly Coles, Xochitl Hernandez-Velasco, Callie Selby, Aaron Forga, Guillermo Tellez-Isaias, Christine Vuong, Lisa Bielke, John Barta, Billy Hargis, Danielle Graham
Summary: Over 100 wild turkey fecal samples were collected from non-commercial turkey production areas in the United States between 2018 and 2020. The presence of anticoccidial-sensitive Eimeria spp. in the samples was confirmed, and their sensitivity to specific anticoccidial drugs was tested.
Article
Agriculture, Dairy & Animal Science
A. L. Kraieski, G. B. C. Salles, E. C. Muniz, D. V. J. Nascimento, A. J. Lima Neto, I. L. Santos, A. M. B. N. Madeira
Summary: Rotation with different active ingredients and ASTs are effective strategies to preserve the efficacy of anticoccidial drugs and reduce resistance. This study evaluated sensitivity of EA and EM isolates from different regions in Brazil using four ASTs, identifying varying levels of drug sensitivity and impact on anticoccidial activity.
Article
Veterinary Sciences
Mingzheng Han, Wenfeng Hu, Tong Chen, Hanxing Guo, Jianfeng Zhu, Feng Chen
Summary: The effects of eight plant extracts and essential oils, as well as their mixture, on the pathogenic parasite Eimeria tenella were investigated. Both in vitro and in vivo studies showed that these extracts and essential oils inhibited the invasion of Eimeria tenella and improved the symptoms of coccidial infection. They have potential as anticoccidial agents.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
M. Glorieux, L. J. Newman, Y-T Wang, P. De Herdt, J. Hautekeur, M. De Gussem, I Christiaens, J. Verbeke
Summary: A study on 27 Eimeria spp. field isolates from 10 European countries found that isolates collected from farms using in-feed anticoccidial medication demonstrated poor sensitivity to narasin + nicarbazin. In contrast, isolates collected from farms using coccidiosis vaccination showed good sensitivity to narasin + nicarbazin.
JOURNAL OF APPLIED POULTRY RESEARCH
(2022)
Article
Veterinary Sciences
Chen Chen, Junzhi Su, Mingmin Lu, Lixin Xu, Ruofeng Yan, Xiangrui Li, Xiaokai Song
Summary: In this study, a DNA vaccine encoding T-cell epitopes derived from common antigens of Eimeria parasites was designed and shown to increase immune responses and alleviate enteric lesions in vaccinated chickens. However, the vaccine's protective efficacy against multiple Eimeria coinfections was not satisfactory.
VETERINARY RESEARCH
(2023)
Article
Parasitology
Thanakarn Nasri, Somboon Sangmaneedet, Nguyen Hoai Nam, Kanlaya Worawong, Weerapol Taweenan, Peerapol Sukon
Summary: The limitations of live oocyst anticoccidial vaccines in poultry have led to the search for new generation vaccines. The protective efficacy of these vaccines is influenced by various factors, such as the vaccine platform and route of administration. Meta-analysis of challenge trials in chickens showed that the new generation of anticoccidial vaccine candidates partially protected against coccidiosis by reducing the lesion score and oocyst output. However, there was high heterogeneity and publication bias, indicating the need for further experimental trials to better understand the protective efficacy.
VETERINARY PARASITOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
R. R. Santos, F. C. Velkers, J. C. M. Vernooij, L. Star, J. L. T. Heerkens, J. van Harn, I. C. de Jong
Summary: Different combinations of gut health-promoting dietary interventions were tested to support broilers during different stages of Eimeria infection. The best feed conversion ratio, as well as lower oocyst output and lesion scores, were observed in broilers that received multispecies probiotics, saponins, artemisin, curcumin, coated butyrate and threonine.
Article
Parasitology
Zhenzhao Zhang, Muzi Li, Junpeng Chen, Jinxuan Li, Nianyuan Chen, Qingyang Song, Xiaomin Zhao, Hongmei Li, Xiao Zhang
Summary: In this study, the natural sesquiterpene alcohol cedrol was found to have an anticoccidial effect in chicks. The chicks administered with cedrol showed reduced oocyst count, increased relative weight gain rate, and decreased severe swelling of the cecum. Cedrol did not have any adverse effects on the chickens' biochemical parameters but altered oxidative stress biomarkers and cytokine levels associated with anticoccidial response, indicating an improved anticoccidial ability.
PARASITOLOGY INTERNATIONAL
(2023)
Article
Parasitology
Jordan Eckert, Miranda Carrisosa, Ruediger Hauck
Summary: The study found that broilers vaccinated against coccidia have similar body weight and feed conversion rate at processing age compared to those given anticoccidial drugs, with results slightly favoring the use of drugs. This meta-analysis also confirmed the robustness of the research and highlighted the need for further investigation into under-researched areas and concerns regarding data quality in coccidia research.
VETERINARY PARASITOLOGY
(2021)
Article
Parasitology
Haixia Wang, Qiping Zhao, Shunhai Zhu, Hui Dong, Shuilan Yu, Qingjie Wang, Yu Yu, Shanshan Liang, Huanzhi Zhao, Bing Huang, Hongyu Han
Summary: Chicken coccidiosis is a major parasitic disease in poultry industry caused by Eimeria genus, with resistance to anticoccidial drugs becoming a growing concern. The study indicated that EtCS may be involved in host cell invasion of E. tenella and contribute to the development of E. tenella resistance to certain drugs.
PARASITOLOGY RESEARCH
(2021)
Article
Environmental Sciences
Mohamed A. Dkhil, Felwa A. Thagfan, Mostafa Y. Morad, Esam M. Al-Shaebi, Sherif Elshanat, Amira A. Bauomy, Murad Mubaraki, Taghreed A. Hafiz, Saleh Al-Quraishy, Rewaida Abdel-Gaber
Summary: This study investigates the action of silver nanoparticles prepared from Zingiber officinale rhizomes in the treatment of mice infected with Eimeria papillata. The results demonstrate that the nanoparticles can improve the jejunal mucosa and reduce the pathological damage associated with the infection.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Agriculture, Dairy & Animal Science
R. P. Snyder, M. T. Guerin, B. M. Hargis, P. S. Kruth, G. Page, E. Rejman, J. L. Rotolo, W. Sears, E. G. Zeldenrust, J. Whale, J. R. Barta
Summary: Increasing resistance of Eimeria species to anticoccidial medications is a concern in the broiler chicken industry. Using drug-sensitive vaccine strains has been shown to enhance anticoccidial effectiveness in Canadian broiler production facilities. However, the requirement to remove litter between flocks under Canadian broiler production rules may limit the establishment of vaccine-strain Eimeria species and potentially reduce the longevity of improved drug sensitivity observed in this study.
Article
Multidisciplinary Sciences
Ali Nouri
Summary: This study investigated the effects of encapsulated organic acids and anticoccidial drugs on the anticoccidial and immunogenic properties of broilers reared on reused infected litter. The results showed that simultaneous feeding of organic acids and anticoccidials significantly improved broiler's production efficiency, survival rate, immunity, and reduced oocyst output and caecal lesion scores. The combination of organic acids and diclazuril had the highest anticoccidial index.
SCIENTIFIC REPORTS
(2022)
Review
Agriculture, Dairy & Animal Science
Radhia Aitfella Lahlou, Mustapha Bounechada, Arezki Mohammedi, Luis R. Silva, Gilberto Alves
Summary: Coccidiosis is a parasitic disease caused by protozoa which affects poultry production significantly. Anticoccidial drugs and vaccination are common preventive measures, but drug resistance and environmental pollutants have led to a search for alternative methods. The use of medicinal plants or plant-derived products could provide a solution, as they contain bioactive compounds that could be developed into new chemical entities.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2021)
Article
Veterinary Sciences
W. J. M. Landman, J. H. H. van Eck
Article
Veterinary Sciences
W. J. M. Landman, K. Huyge, J. P. Remon, C. Vervaet, J. H. H. van Eck
Article
Veterinary Sciences
R. Dijkman, A. Feberwee, W. J. M. Landman
Article
Veterinary Sciences
W. J. M. Landman, R. J. Molenaar, A. Cian, H. M. J. F. van der Heijden, E. Viscogliosi
Editorial Material
Veterinary Sciences
W. J. M. Landman, J. H. H. van Eck
Article
Veterinary Sciences
W. J. M. Landman, E. A. Germeraad, M. J. Kense
Article
Veterinary Sciences
T. T. M. Manders, M. G. R. Matthijs, S. Veraa, J. H. H. van Eck, W. J. M. Landman
Summary: The study examined the success rates of inoculating chicken embryos in brown eggs and found that targeting albumen, yolk, amniotic cavity, and embryo yielded low scores. Magnetic resonance imaging was used to understand the reasons behind this, leading to adjustments in the inoculation method. Despite challenges, full scores were obtained for most compartments, making this study a useful guide for future inoculation procedures.
Article
Veterinary Sciences
W. J. M. Landman, N. Gantois, M. Sawant, F. A. Majoor, J. H. H. van Eck, E. Viscogliosi
Summary: Trichomonads are prevalent among wetland birds in the Netherlands, with Tetratrichomonas gallinarum being the dominant species. The potential impact of these infections on commercial poultry is raised as a concern.
Article
Veterinary Sciences
W. J. M. Landman, G. J. Buter, R. Dijkman, J. H. H. van Eck
Summary: Fourteen genetically different chicken Escherichia coli strains were biotyped in hens to examine their ability to induce E. coli peritonitis syndrome (EPS). Strains from bone marrow and pericardium were found to be associated with EPS, while strains from other sources were not. The embryo lethality test showed good reproducibility and can be considered a useful alternative for biotyping E. coli in productive hens.
Article
Veterinary Sciences
T. T. M. Manders, J. H. H. van Eck, G. J. Buter, W. J. M. Landman
Summary: The study aimed to determine the best inoculation route for virulotyping E. cecorum strains in a chicken embryo lethality assay. The albumen inoculation route showed the greatest difference in mortality between cloaca and lesion strains, making it the most suitable route for virulotyping.
Article
Veterinary Sciences
W. J. M. Landman, C. Vervaet, J. P. Remon, K. Huyge, J. H. H. van Eck
Article
Veterinary Sciences
R. Dijkman, A. Feberwee, W. J. M. Landman
Article
Veterinary Sciences
A. Feberwee, R. Dijkman, D. Klinkenberg, W. J. M. Landman
Article
Veterinary Sciences
W. J. M. Landman, J. H. H. van Eck
Article
Veterinary Sciences
H. W. Peek, C. ter Veen, R. Dijkman, W. J. M. Landman