Review
Endocrinology & Metabolism
Michelle Henry, Kevin Garth Flusk Thomas, Ian Louis Ross
Summary: Sleep is critical for cognitive well-being and disruptions can lead to memory deficits, with cortisol levels potentially playing a role in this relationship. Patients with AD experience disrupted sleep and impaired memory due to consistent cortisol imbalances from glucocorticoid therapy, highlighting the importance of restoring a normal circadian rhythm. Future initiatives should focus on improving cognitive performance and quality of life for AD patients through prioritizing and optimizing sleep.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Xiao-Qian Chen, Xiu-Min Jiang, Qing-Xiang Zheng, Hai-Wei Wang, Heng Xue, Yu-Qing Pan, Yan-Ping Liao, Xiao-Xia Gao
Summary: This study aimed to explore the factors influencing sub-health and circadian rhythm disorder among midwives and examine the relationship between circadian rhythm disorder and sub-health. A cross-sectional study was conducted among 91 Chinese midwives from six hospitals using cluster sampling. The results showed that sub-health and circadian rhythm disorder were common among midwives and were significantly related to age, exercise duration, working hours, job satisfaction, cortisol rhythm, and melatonin rhythm. Nurse administrators should take measures to prevent sub-health and circadian rhythm disorder among midwives.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Agriculture, Dairy & Animal Science
Lisandro Munoz, Tomas Salazar, Camila Donaire, Reinaldo Ortiz, Jaime Cruces, Mario Briones
Summary: This study aimed to estimate the heritability of crib-biting in Chilean horses. The prevalence of crib-biting was found to be 4%, more common in males, with a heritability of 0.229, indicating it follows a quantitative model of inheritance with moderate to low additive genetic factors.
Article
Behavioral Sciences
Amanda C. dos Santos, Murilo S. de Abreu, Gabriel P. de Mello, Vanusa Costella, Nicoli R. do Amaral, Alexander Zanella, Julia Poletto, Elena Petersen, Allan Kalueff, Ana C. V. V. Giacomini
Summary: Music therapy has positive effects on improving cognitive function and mood in humans and animals. This study examines the impact of solfeggio-frequency music exposure on behavior, cognition, and endocrine parameters in adult zebrafish that were subjected to a disturbance in circadian rhythm. It was found that continuous exposure to music for 24 hours or intermittent exposure for 2 or 6 hours twice daily reversed the cognitive deficits and elevated cortisol levels caused by 24-hour light exposure. These findings highlight the positive modulation of cognitive and endocrine responses in adult zebrafish through long-term music exposure.
BEHAVIOURAL BRAIN RESEARCH
(2023)
Article
Anesthesiology
Jingjing Li, Shining Cai, Xiao Liu, Jinghua Mei, Wenyan Pan, Ming Zhong, Yuxia Zhang
Summary: This study investigated the relationship between delirium and the circadian rhythms of melatonin, cortisol, and sleep in ICU patients. The results showed that the disturbance of melatonin and cortisol secretion rhythms was associated with the development of delirium. Therefore, it is important for clinical staff to pay attention to maintaining normal circadian rhythms in ICU patients.
BMC ANESTHESIOLOGY
(2023)
Article
Psychiatry
Zheng Xie, Yajie Deng, Chunyu Xie, Yuanlong Yao
Summary: The objective of this study was to explore the rhythm of adrenocorticotropic hormone (ACTH) and cortisol in patients with depression and anxiety, and their effects on mental state. A diagnosis model based on artificial intelligence (AI) showed high recognition accuracy for depression. The study found that depression with anxiety had a higher severity level and a higher incidence of cortisol rhythm disorder, indicating different effects on the mental state of patients.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Environmental Sciences
Zihe Zhao, Yushi Yu, Huiyan Wang, Xiyuan Huang, Peng Ding, Yingzhuo Sun, Jun Ding, Yaqing Chang, Chong Zhao
Summary: The study found that sea cucumbers exhibit different behavioral and physiological responses to the circadian rhythm. These findings suggest that aqua-farmers should consider carrying out seeding at night and providing diets before the peak of sea cucumber feeding at night. The study also revealed that cortisol concentration is higher at night, indicating that sea cucumbers may be more stressed during this time. However, 5-HT and melatonin are not significantly affected by the circadian rhythm. Overall, this study provides valuable insights into the behavior and physiology of sea cucumbers and their aquaculture.
MARINE ENVIRONMENTAL RESEARCH
(2023)
Article
Endocrinology & Metabolism
Weiying Dai, Swanand A. Wagh, Steffi Chettiar, Grace D. Zhou, Runia Roy, Xingye Qiao, Paul S. Visich, Eric P. Hoffman
Summary: This study found that circadian cortisol levels in children are associated with cardiovascular health outcomes, with lower morning cortisol levels being linked to increased blood pressure, body fat, and poor lipid profiles. Adjusting for potential confounding variables revealed that lower morning cortisol levels in 4th grade were associated with increased blood pressure a year later.
PSYCHONEUROENDOCRINOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Wanxin Tang, Lu Yin, Juliane R. Sempionatto, Jong-Min Moon, Hazhir Teymourian, Joseph Wang
Summary: The new touch-based non-invasive cortisol sensor allows for rapid, simple, and reliable detection of cortisol in sweat, with highly selective binding and direct electrical signaling. Additionally, the use of highly permeable sweat-wicking porous hydrogel enables convenient and rapid collection of instantly secreted fingertip sweat.
ADVANCED MATERIALS
(2021)
Review
Behavioral Sciences
Roberto Zefferino, Sante Di Gioia, Massimo Conese
Summary: The article reviews the complex relations among important molecules in the CNS, IS, and ES during chronic stress. A speculative hypothesis is proposed regarding the interplay of signaling molecules, with IL-1beta highlighted as a main biomarker of these effects.
BRAIN AND BEHAVIOR
(2021)
Article
Public, Environmental & Occupational Health
Xin-xin Huang, Xiu-min Jiang, Qing-Xiang Zheng, Xiao-Qian Chen
Summary: The study explored the association between cortisol rhythm trends and shift work regularity in midwives. Results showed a circadian rhythm in cortisol secretion among midwives, with slightly lower fluctuation range in those with irregular shift patterns. Shift work regularity significantly impacted cortisol levels independent of total working hours per week.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Biochemistry & Molecular Biology
Guobin Huang, Huan Ma, Xihui Gan, Silin Li, Xiaohong Ma, Siyu Chen, Huiying Yang, Xinhai Zhu, Hongmei Jiang, Qian Bi, Yongcong Shao, Yebing Yang, Jinhu Guo
Summary: The study revealed that non-24 h and shift schedules can disrupt circadian rhythms and lead to changes in blood/serum variables, including increased phosphate levels. miRNA regulation of genes related to phosphate transport may play a key role in affecting serum phosphate levels.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2021)
Article
Biophysics
Gopi Karuppaiah, Min-Ho Lee, Shekhar Bhansali, Pandiaraj Manickam
Summary: Psychological stress plays a significant role in health disparities among individuals, and the release of cortisol is a crucial response to stress. Electrochemical sensing has emerged as a reliable method for cortisol detection, and this review focuses on the progress made in electrochemical sensors, their design, principles, and analytical methodologies. The challenges faced in the development of electrochemical cortisol sensors are also discussed, highlighting the need for more sensitive electrodes and materials.
BIOSENSORS & BIOELECTRONICS
(2023)
Review
Clinical Neurology
Emily J. Ricketts, Daniel S. Joyce, Ariel J. Rissman, Helen J. Burgess, Christopher S. Colwell, Leon C. Lack, Michael Gradisar
Summary: Light exposure plays a significant role in regulating circadian rhythms, and disruptions to this regulation can lead to various impairments. This is particularly relevant for adolescents, whose sleep-wake patterns are affected by reduced daytime light exposure and prolonged use of electronic devices in the evening. Implementing measures to adjust light intensity, spectra, duration, and delivery modality can support the sleep-wake health of adolescents in different contexts.
SLEEP MEDICINE REVIEWS
(2022)
Review
Cell Biology
Yihao Tian, Jian Ming
Summary: Osteoporosis is a common and impactful disease with no known treatments. Recent studies have shown that melatonin can be used to treat osteoporosis by regulating biological rhythms in bone tissue, promoting bone formation and inhibiting bone resorption. This review provides an overview of these processes and offers treatment and management strategies for individuals with osteoporosis.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Pharmacology & Pharmacy
Magdy Adam, Jere Linden, Marja Raekallio, Anna Meller, Bettina Mannerstrom, Ahmed Abu-Shahba, Riitta Seppanen-Kaijansinkko, Kati Salla
Summary: The study found that premedication with vatinoxan can alleviate xylazine-induced pulmonary alterations, but may lead to other histological changes. The decrease in oxygen saturation caused by xylazine was prevented by premedication with vatinoxan.
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
(2022)
Article
Veterinary Sciences
Ninja P. Karikoski, Justin R. Box, Anna K. Mykkanen, Veikko V. Kotiranta, Marja R. Raekallio
Summary: The study found that the oral sugar test results and adiponectin plasma concentration do not vary with season, but there were a substantial number of horses with variable insulin dysregulation status throughout the year, in which repeated OSTs may be beneficial. Lack of exercise was identified as a risk factor for insulin dysregulation.
EQUINE VETERINARY JOURNAL
(2022)
Article
Multidisciplinary Sciences
Antti Vehkaoja, Sanni Somppi, Heini Tornqvist, Anna Valldeoriola Cardo, Pekka Kumpulainen, Heli Vaataja, Paivi Majaranta, Veikko Surakka, Miiamaaria V. Kujala, Outi Vainio
Summary: This study collected movement sensor data from 45 middle to large sized dogs, including both static and dynamic behaviors. The annotated data, obtained through post-hoc annotation of video recordings, was used to train behavior classification machine learning algorithms.
Article
Veterinary Sciences
Hanna Nurmi, Sauli Laaksonen, Marja Raekallio, Laura Ha euro Nninen
Summary: This study investigated the pharmacokinetics of orally and intravenously administered meloxicam in semi domesticated reindeer. The results showed that both routes of administration maintained therapeutic concentration of meloxicam in reindeer plasma for up to 3 days without evident adverse effects.
VETERINARY ANAESTHESIA AND ANALGESIA
(2022)
Article
Agriculture, Dairy & Animal Science
Sanni Somppi, Heini Tornqvist, Aija Koskela, Antti Vehkaoja, Katriina Tiira, Heli Vaataja, Veikko Surakka, Outi Vainio, Miiamaaria Kujala
Summary: The relationship between owner and dog has an impact on the emotional reactions and stress coping of the dog. Both negative and positive situations can provoke emotional arousal in dogs. The dog-owner relationship influences the dog's emotional reactions, with emotional closeness associated with a secure base effect and shared activities leading to attachment-related arousal.
Article
Agriculture, Dairy & Animal Science
Hanna Nurmi, Sauli Laaksonen, Taija Haatyla, Anna Valros, Mikaela Sauvala, Laura Hanninen
Summary: This study aimed to investigate the effects of castration on reindeer behavior and rectal temperature, and the impact of handling, lidocaine anesthesia, and meloxicam on these factors. The results showed that reindeer displayed pain-related behaviors during castration, and local lidocaine anesthesia did not significantly reduce the pain. In addition, prolonged handling time increased the rectal temperature of reindeer.
APPLIED ANIMAL BEHAVIOUR SCIENCE
(2022)
Article
Behavioral Sciences
Lilli Frondelius, Heli Lindeberg, Matti Pastell
Summary: This study aimed to investigate the normalization of behavior data and the impact of lameness on lying and feeding behaviors in dairy cows. By ranking cows and analyzing behaviors, the study found that rank order variables have potential applications in the development of automated lameness detection systems.
JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH
(2022)
Article
Veterinary Sciences
Vilhelmiina Huuskonen, Flavia Restitutti, Marja Raekallio, Juhana Honkavaara, Tommi Pesonen, Outi Vainio
Summary: This study aimed to determine whether dobutamine, norepinephrine, or phenylephrine infusions can alleviate hypotension in isoflurane-anesthetized dogs administered dexmedetomidine and vatinoxan. The results showed that both dobutamine and norepinephrine were effective in treating hypotension in these dogs.
VETERINARY ANAESTHESIA AND ANALGESIA
(2022)
Article
Veterinary Sciences
Kati M. Salla, Heta A. Turunen, Ira J. Kallio-Kujala, Vuokko Pekkola, Daniela C. Casoni, Jaan Lepajoe, Pia Bjorkenheim, Marja R. Raekallio, Outi Vainio
Summary: The study investigated the effects of vatinoxan on dogs undergoing anaesthesia for surgical castration. It found that vatinoxan administration resulted in hypotension compared to the control group, with no significant differences in other physiological variables or anaesthetic quality.
VETERINARY ANAESTHESIA AND ANALGESIA
(2022)
Article
Veterinary Sciences
Tuuli Laukkanen, Leena Karma, Anna-Maija Virtala, Anna Mykkanen, Jaana Pehkonen, Heini Rossi, Kati Tuomola, Marja Raekallio
Summary: The study aimed to determine the dental findings that may cause behavioral signs associated with dental pain. It found that broadened or darkened fissures, complicated fractures, and secondary dentine defects were associated with various behavioral signs in horses. The results suggest that horses with these potentially painful dental problems may require intervention if they exhibit behavioral signs related to dental pain.
JOURNAL OF EQUINE VETERINARY SCIENCE
(2023)
Article
Pathology
Jere Linden, Suvi Taponen, Vera Talvitie, Eveliina Leppavori, Laura Hanninen
Summary: This study describes the histological tissue damage and healing process in dairy calves disbudded using cauterization or alkaline caustic paste application. The caustic paste disbudding resulted in more severe and extensive necrosis compared to cauterization, and took longer to heal.
JOURNAL OF COMPARATIVE PATHOLOGY
(2023)
Article
Chemistry, Analytical
Victor Bloch, Lilli Frondelius, Claudia Arcidiacono, Massimo Mancino, Matti Pastell
Summary: Due to technological developments, wearable sensors for monitoring farm animal behavior have become more affordable, durable, and accessible for small farms and researchers. Advances in deep machine learning methods offer new opportunities for behavior recognition. This study trained a CNN-based model to classify feeding behavior in dairy cows and analyzed the training process with a dataset and transfer learning. The findings provide insights into the necessary dataset size and accuracy of neural network classifiers for different environments.
Article
Pharmacology & Pharmacy
Annemari Jokela, Alexandra Nyrhila, Magdy Adam, Kati Salla, Marja Raekallio, Riikka Aho, Marianna Norring, Ann-Helena Hokkanen
Summary: The pharmacokinetics of Meloxicam were studied in pre-ruminant calves after intravenous, subcutaneous, and oral administration, and the results showed high bioavailability and prolonged elimination half-lives for the subcutaneous and oral routes.
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
(2023)
Article
Multidisciplinary Sciences
Rafael Munoz-Tamayo, Birte L. Nielsen, Mohammed Gagaoua, Florence Gondret, E. Tobias Krause, Diego P. Morgavi, I. Anna S. Olsson, Matti Pastell, Masoomeh Taghipoor, Luis Tedeschi, Isabelle Veissier, Christian Nawroth
Summary: This article provides practical steps to embrace Open Science in animal science, aiming to promote the field's development, increase public trust, and address future challenges.
Article
Education & Educational Research
Liisa Myyry, Terhi Karaharju-Suvanto, Anna-Maija K. Virtala, Marja R Raekallio, Outi Salminen, Marjo Vesalainen, Anne Nevgi
Summary: Based on social cognitive theory, this study investigated how self-efficacy beliefs were linked to assessment practices among experienced university teachers. The data from 16 thematic interviews of award-winning teachers revealed that mastery experience was the primary source of self-efficacy in assessment, with fairness being a prominent feature in assessment for experienced teachers.
ASSESSMENT & EVALUATION IN HIGHER EDUCATION
(2022)
Article
Veterinary Sciences
L. Alibrandi, R. Tognetti, O. Domenech, M. Croce, M. Giuntoli, G. Grosso, T. Vezzosi
Summary: This study assessed the feasibility and diagnostic reliability of a new smartphone-based ECG device in dogs, and found no significant differences compared to a traditional ECG device. The results suggest that the smartphone-based device is clinically reliable for assessing heart rate and rhythm in dogs.
VETERINARY JOURNAL
(2024)
