Article
Microbiology
Eva Conkova, Martina Proskovcova, Peter Vaczi, Zuzana Malinovska
Summary: This study aimed to investigate the intensity of biofilm production by Malassezia pachydermatis strains isolated from the ear canal of healthy dogs and determine their susceptibility to three commonly used azole antifungal drugs. The results showed that higher concentrations of antifungal agents are needed to treat infections caused by biofilm-forming strains of M. pachydermatis.
Article
Agriculture, Dairy & Animal Science
Ifarajimi Rapheal Olabode, Nadezhda Sachivkina, Arfenia Karamyan, Ramziya Mannapova, Olga Kuznetsova, Anna Bobunova, Natallia Zhabo, Marina Avdonina, Regina Gurina
Summary: Despite the development of new antimycotic drugs, drug resistance remains a major clinical challenge in the treatment of fungal infections. The use of phytopreparations with direct fungicidal effects on fungal biofilms is of great interest. This research focused on studying the biofilm infection caused by Malassezia pachydermatis, identifying the most resistant strains to antimycotics, investigating the correlation between resistance and biofilm formation, and examining the effect of Farnesol on biofilms. The study provided evidence for the relationship between biofilm density and drug sensitivity, and showed the antibiofilm effect of Farnesol at different concentrations.
Article
Mycology
Leyna Diaz, Gemma Castella, M. Rosa Bragulat, F. Javier Cabanes
Summary: In this study, the in vitro antifungal susceptibility of 89 strains of M. pachydermatis was investigated. The results showed that four antifungal drugs were highly effective against most strains. Additionally, a high diversity of ERG11 gene sequences was observed, with several mutations associated with reduced susceptibility to azoles.
Review
Microbiology
Dorota Chrobak-Chmiel, Anna Golke, Ewelina Kwiecien, Malgorzata J. Bieganska, Kourou Dembele, Malgorzata Dziekiewicz-Mrugasiewicz, Michal Czopowicz, Magdalena Kizerwetter-Swida, Magdalena Rzewuska
Summary: Canine atopic dermatitis (CAD) is a common inflammatory skin disease in dogs, with secondary organisms overgrowth and skin infections. The causes of this disease are not fully understood, so lifelong symptomatic treatment is the only option.
Article
Veterinary Sciences
Brooke D. Esquivel, Elisa M. Rouse Salcido, Allison M. Schweiker, Brandon L. Holder, Butch Kukanich, Kate S. Kukanich, Theodore C. White
Summary: The purpose of this study was to characterize the oral mycobiome of domestic dogs and identify potential pathogenic fungi. Samples were obtained from 251 dogs and analyzed using DNA sequencing and drug susceptibility tests. The findings highlight the importance of understanding the oral mycobiome for canine dental hygiene, health, and medical treatment, as well as the potential transmission of fungal pathogens from dogs to humans.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Veterinary Sciences
Nobuo Murayama, Rui Kano
Summary: This study aimed to determine the most effective drug against azole-resistant M. pachydermatis. Susceptibility to azoles and terbinafine was evaluated using a modified broth microdilution method. The results showed that the strains with low susceptibility to azoles were relatively susceptible to terbinafine.
JOURNAL OF VETERINARY MEDICAL SCIENCE
(2023)
Article
Microbiology
Fabrizio Bertelloni, Giulia Cagnoli, Valentina Virginia Ebani
Summary: Dogs can harbor different species of Staphylococcus and can develop various clinical forms caused by these bacteria. Most of the clinical Staphylococcus isolates cultured from sick dogs were Staphylococcus pseudointermedius, with common characteristics including gelatinase, biofilm, and slime production, as well as high levels of multi-drug resistance.
Article
Cell Biology
Andrea J. Wolf, Jose J. Limon, Christopher Nguyen, Alexander Prince, Anthony Castro, David M. Underhill
Summary: Malassezia spp. yeasts are commonly found on mammalian skin, but can also be found in the intestines in certain diseases. They induce inflammatory responses by activating proinflammatory cytokine production, mainly through the Dectin2 and CARD9 signaling pathways, and stimulate NLRP3 inflammasome activation.
JOURNAL OF LEUKOCYTE BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Fahimeh Hashemi Arani, Stephanie Kadow, Melanie Kramer, Simone Keitsch, Lisa Kirchhoff, Fabian Schumacher, Burkhard Kleuser, Peter-Michael Rath, Erich Gulbins, Alexander Carpinteiro
Summary: This study found that sphingosine is effective in prophylaxis against Aspergillus spp. and Candida spp. It improves survival rates in mice with invasive aspergillosis and induces apoptosis through mitochondrial depolarization and cytochrome C release. Inhaled sphingosine shows promise as a prophylactic agent against pulmonary aspergillosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Microbiology
Magdalena Frej-Madrzak, Sabina Golec, Katarzyna Wlodarczyk, Irena Choroszy-Krol, Urszula Nawrot
Summary: The study aimed to determine the susceptibility of 125 Candida isolates from the genitourinary system of hospitalized patients and outpatients to clotrimazole. Most isolates showed sensitivity to clotrimazole, but there was a trend of increasing resistant isolates.
Article
Infectious Diseases
Marianne Moerer, Antina Luebke-Becker, Astrid Bethe, Roswitha Merle, Wolfgang Baeumer
Summary: The aim of this study was to investigate the impact of the second amendment to the Regulation of Veterinary Pharmacies (TaHAV) in 2018 on the occurrence of antimicrobial resistance in selected bacterial pathogens isolated from dogs and cats in Germany. The study found that the amendment led to an increase in sample submissions in Germany. The highest resistance rates were found for Staphylococcus pseudintermedius, Staphylococcus aureus, and Escherichia coli, while resistance rates were low for Pasteurella multocida and β-hemolytic streptococci. Significant decreases in resistance rates were observed for S. pseudintermedius against penicillin G and ampicillin, S. felis against amoxicillin-clavulanic acid and cefovecin, and S. aureus against enrofloxacin.
Article
Reproductive Biology
Wallaya Phongphaew, Mintraporn Kongtia, Kiyeon Kim, Kaitkanoke Sirinarumitr, Theerapol Sirinarumitr
Summary: The study compared the prevalence of bacterial species and results of drug susceptibility testing of bacteria isolated from prostatic fluids and urine samples from dogs with prostatitis and cystitis. Staphylococcus spp., Escherichia coli, Pseudomonas spp., Streptococcus spp., Proteus mirabilis, and Klebsiella pneumoniae were the major species detected, with Staphylococcus spp. and Escherichia coli being the most prevalent. Imipenem and gentamicin were found to be the most potent antimicrobial drugs, but caution is needed when administering imipenem for treating prostatitis and cystitis in dogs. Additionally, there were no significant differences in antimicrobial drug susceptibility trends between prostatic fluid and urine samples.
Article
Infectious Diseases
Florencia Dinorah Rojas, Maria de los Angeles Sosa, Wenceslao Latorre, Javier Mussin, Liliana Alegre, Gustavo Giusiano
Summary: Malassezia yeasts are common in human skin microbiome and can cause various diseases. This study proposes tentative epidemiological cutoff values (ECVs) for three Malassezia species against five antifungal drugs, which can be helpful in guiding therapy decisions.
Article
Microbiology
Brooke Rathie, Bart Theelen, Martin Laurence, Rebecca S. Shapiro
Summary: This study tested the efficacy of four antifungal drugs against three Malassezia species, finding new drugs isavuconazole and artemisinin with antifungal properties. Itraconazole was found most effective against Malassezia. This research is important for identifying effective antifungal therapies.
MICROBIOLOGY SPECTRUM
(2023)
Article
Immunology
Ming-Chi Li, Hung-Jen Tang, Chi-Jung Wu, Shin-Wei Wang, Shu-Li Su, Wei-Lun Liu, Wen-Chien Ko, Yee-Chun Chen
Summary: This study aimed to compare the identification performance of two MALDI-TOF MS systems and an oligonucleotide array for uncommon Candida species isolates. The results showed that the oligonucleotide array and the two MALDI-TOF MS systems had high identification rates for these isolates. Elevated fluconazole minimal inhibitory concentrations were observed for some uncommon Candida species.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2022)
Article
Biology
Maria Samires Martins Castro, Angela Maria de Vasconcelos, Raquel Oliveira dos Santos Fontenelle, Murilo Sergio da Silva Juliao, Ana Thais Lira Soares, Leonardo Costa da Silva, Francisco Jeffessor Soares de Sousa, Robson Mateus Freitas Silveira
Summary: This study aimed to analyze the factors that affect water quality for small ruminants in the Brazilian semiarid region, finding high levels of total coliform, Escherichia coli, and nitrate in the water samples. The implementation of preventive measures, such as regular cleaning of drinkers and chlorination, is necessary to guarantee adequate water consumption for the animals.
BIOLOGICAL RHYTHM RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Fernando M. Sombra, Ana Rosa Richter, Alyne Rodrigues de Araujo, Fabio de Oliveira Silva Ribeiro, Josilayne de Fatima Souza Mendes, Raquel Oliveira dos Santos Fontenelle, Durcilene Alves da Silva, Haroldo C. B. Paula, Judith P. A. Feitosa, Francisco M. Goycoolea, Regina C. M. de Paula
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Biotechnology & Applied Microbiology
F. L. L. de Aguiar, C. S. D. P. Cavalcante, R. O. dos Santos Fontenelle, C. B. Falcao, D. Andreu, G. Radis-Baptista
JOURNAL OF APPLIED MICROBIOLOGY
(2020)
Article
Microbiology
Rossana de A. Cordeiro, Fernando V. M. Portela, Livia M. G. Pereira, Ana R. C. de Andrade, Jose K. de Sousa, Ana L. R. Aguiar, Mariana L. M. Pergentino, Gyrliane S. de Sales, Jonathas S. de Oliveira, Delia J. A. Medrano, Raimunda S. N. Brilhante, Marcos F. G. Rocha, Debora de S. C. M. Castelo-Branco, Jose J. C. Sidrim
FUTURE MICROBIOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Lana Glerieide Silva Garcia, Glaucia Morgana de Melo Guedes, Xhaulla Maria Quariguasi Cunha Fonseca, Waldemiro Aquino Pereira-Neto, Debora Souza Collares Maia Castelo-Branco, Jose Julio Costa Sidrim, Rossana de Aguiar Cordeiro, Marcos Fabio Gadelha Rocha, Rodrigo Silveira Vieira, Raimunda Samia Nogueira Brilhante
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Infectious Diseases
Debora de Souza Collares Maia Castelo-Branco, Manoel de Araujo Neto Paiva, Carlos Eduardo Cordeiro Teixeira, Erica Pacheco Caetano, Glaucia Morgana de Melo Guedes, Rossana de Aguiar Cordeiro, Raimunda Samia Nogueira Brilhante, Marcos Fabio Gadelha Rocha, Jose Julio Costa Sidrim
Article
Infectious Diseases
Raimunda Samia Nogueira Brilhante, Wilker Jose Perez Gotay, Vandbergue Santos Pereira, Jonathas Sales de Oliveira, Waldemiro Aquino Pereira-Neto, Debora de Souza Collares Maia Castelo-Branco, Rossana de Aguiar Cordeiro, Jose Julio Costa Sidrim, Marcos Fabio Gadelha Rocha
Article
Mycology
A. M. Rodrigues, M. A. Beale, F. Hagen, M. C. Fisher, P. P. D. Terra, S. de Hoog, R. S. N. Brilhante, R. de Aguiar Cordeiro, D. de Souza Collares Maia Castelo-Branco, M. F. G. Rocha, J. J. C. Sidrim, Z. P. de Camargo
STUDIES IN MYCOLOGY
(2020)
Article
Microbiology
Jose J. C. Sidrim, Crister J. Ocadaque, Bruno R. Amando, Glaucia M. Guedes, Cecilia L. Costa, Raimunda S. N. Brilhante, Rossana de Cordeiro, Marcos F. G. Rocha, Debora SCM Castelo-Branco
FUTURE MICROBIOLOGY
(2020)
Review
Biotechnology & Applied Microbiology
Debora de Souza Collares Maia Castelo-Branco, Bruno Rocha Amando, Crister Jose Ocadaque, Lara de Aguiar, Debora Damasio de Queiroz Paiva, Expedito Maia Diogenes, Glaucia Morgana de Melo Guedes, Cecilia Leite Costa, Anisio Silvestre Pinheiro Santos-Filho, Ana Raquel Colares de Andrade, Rossana de Aguiar Cordeiro, Marcos Fabio Gadelha Rocha, Jose Julio Costa Sidrim
Article
Chemistry, Inorganic & Nuclear
Talles Andre Feitosa de Carvalho, Francisco Xavier Nobre, Amanda de Lima Barros, Anupama Ghosh, Andre de Almeida Lima e Silva, Raquel Oliveira dos Santos Fontenelle, Maria Rita de Morais Chaves Santos, Jose Milton Elias de Matos
Summary: Lindgrenite microstructures were obtained through different synthesis methods, exhibiting good optical properties and thermal stability, showing promising antifungal performance against Candida albicans and Trichophyton rubrum.
JOURNAL OF SOLID STATE CHEMISTRY
(2021)
Article
Chemistry, Medicinal
Vanessa Moreira Frota, Francisco Matheus F. Dias, Mariana Ferreira do Nascimento, Lavosyer da Silva Mendonca, Emanuella Cristina dos Santos Moita, Laressa Cristyne dos Santos Gomes, Antonio Linkoln Alves Borges Leal, Humberto Medeiros Barreto, Maria Francilene Souza Silva, Raquel Oliveira dos Santos Fontenelle, Geovany Amorim Gomes, Jean Parcelli C. do Vale, Murilo Sergio da Silva Juliao, Paulo Nogueira Bandeira, Claudia do O. Pessoa, Helcio Silva dos Santos, Guilherme Juliao Zocolo, Tigressa Helena S. Rodrigues
Summary: Brown propolis from Brazil contains mainly sesquiterpenes and an apolar fraction, with potential biological activities in combating Staphylococcus aureus infections and as an alternative treatment for cancer.
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
(2021)
Review
Agriculture, Dairy & Animal Science
Maria Gleiciane Soares Coutinho, Andrea Maria Neves, Ana Sancha Malveira Batista, Raquel Oliveira dos Santos Fontenelle
JOURNAL OF CANDIDO TOSTES DAIRY INSTITUTE
(2020)
Article
Biology
Antonio Carlos Nogueira Sobrinho, Helcio Silva dos Santos, Selene Maia de Morais, Carolina Sidrim de Paula Cavalcante, Elnatan Bezerra de Souza, Halisson Araujo de Sousa, Maria Rose Jane Ribeiro Albuquerque, Raquel Oliveira dos Santos Fontenelle
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
(2020)
Article
Chemistry, Multidisciplinary
P. T. Silva, L. M. A. Lopes, J. C. Xavier, M. C. S. Carvalho, M. O. Moraes, C. Pessoa, F. W. A. Barros-Nepomuceno, P. N. Bandeira, C. S. P. C. Targino, A. M. R. Teixeira, R. O. S. Fontenelle, H. S. Santos
REVISTA VIRTUAL DE QUIMICA
(2020)
Article
Veterinary Sciences
L. Alibrandi, R. Tognetti, O. Domenech, M. Croce, M. Giuntoli, G. Grosso, T. Vezzosi
Summary: This study assessed the feasibility and diagnostic reliability of a new smartphone-based ECG device in dogs, and found no significant differences compared to a traditional ECG device. The results suggest that the smartphone-based device is clinically reliable for assessing heart rate and rhythm in dogs.
VETERINARY JOURNAL
(2024)