Review
Biochemistry & Molecular Biology
Michael N. Armitage, Daniella A. Spittle, Alice M. Turner
Summary: A systematic review and meta-analysis found that approximately 41% of patients with stable COPD have potentially pathogenic microorganisms (PPMs) in their sputum. The most common PPMs reported were H. influenzae, M catarrhalis, S. pneumoniae, S. aureus, and P. aeruginosa. There was a weak correlation between declining lung function and prevalence of PPMs.
Article
Environmental Sciences
Humairat H. Rahman, Danielle Niemann, Stuart H. Munson-McGee
Summary: This study investigated the correlation between asthma, emphysema, chronic bronchitis, chronic obstructive lung disease (COPD) and lung cancer in the US adult population. The study found a significant correlation between emphysema, chronic bronchitis, COPD and lung cancer. However, no correlation was established between asthma and lung cancer.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Respiratory System
Nicola Murgia, Angela Gambelunghe
Summary: Chronic obstructive pulmonary disease (COPD) is primarily caused by smoking and occupational exposure, with the latter often being underestimated. Early diagnosis, identification of occupational causes, and collaborative treatment are crucial for preventing further decline in lung function and reducing the burden of COPD.
Article
Medicine, General & Internal
Alvise Casara, Graziella Turato, Marta Marin-Oto, Umberto Semenzato, Davide Biondini, Mariaenrica Tine, Nicol Bernardinello, Elisabetta Cocconcelli, Pablo Cubero, Elisabetta Balestro, Paolo Spagnolo, Jose M. Marin, Manuel G. Cosio, Marina Saetta, Erica Bazzan
Summary: Chronic bronchitis (CB) significantly affects symptoms, quality of life, and survival in smokers without COPD, with 27% of noCOPD smokers having CB. CB does not impact FEV1 decline in noCOPD but does significantly in COPD patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
D. Pellegrino, S. Casas-Recasens, R. Faner, P. Palange, A. Agusti
Summary: The term GETomics refers to the concept that human health and disease are the result of dynamic gene-environment interactions occurring throughout a person's lifetime. This approach has led to a dramatic shift in our understanding of chronic obstructive pulmonary disease (COPD), as it is not solely caused by smoking and affects both genders and different age groups. By applying a GETomics approach, new perspectives on the relationship between COPD, exercise limitation, and aging can be gained.
RESPIRATORY MEDICINE
(2023)
Article
Medicine, General & Internal
Sandra Casas-Recasens, Nuria Mendoza, Alejandra Lopez-Giraldo, Tamara Garcia, Borja G. Cosio, Sergi Pascual-Guardia, Ady Acosta-Castro, Alicia Borras-Santos, Joaquim Gea, Gloria Garrabou, Alvar Agusti, Rosa Faner
Summary: The study suggests a link between respiratory diseases such as COPD and accelerated ageing. Telomere length may be associated with lung function impairment, and there are differences in mitochondrial function in COPD patients of different age groups.
FRONTIERS IN MEDICINE
(2021)
Review
Medicine, Research & Experimental
Michael C. Ferrera, Wassim W. Labaki, MeiLan K. Han
Summary: COPD is a common respiratory disorder with high morbidity and mortality, often underdiagnosed until clinical advancement. Research focuses on early changes for better diagnosis and identifying patients for early intervention. Treatment options have significantly expanded in the past 20 years with new medications and procedures.
ANNUAL REVIEW OF MEDICINE, VOL 72, 2021
(2021)
Review
Environmental Sciences
Priya Upadhyay, Ching-Wen Wu, Alexa Pham, Amir A. Zeki, Christopher M. Royer, Urmila P. Kodavanti, Minoru Takeuchi, Hasan Bayram, Kent E. Pinkerton
Summary: Chronic obstructive pulmonary disease (COPD) is a major cause of mortality globally, characterized by lung damage, inflammation, and airflow obstruction. Tobacco smoking is the primary cause, but exposure to air pollutants and workplace fumes also contribute. Animal models have helped to improve our understanding of COPD pathogenesis and potential treatments.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS
(2023)
Review
Cardiac & Cardiovascular Systems
Alvar Agusti, Michael Bohm, Bartolome Celli, Gerard J. Criner, Ana Garcia-Alvarez, Fernando Martinez, Don D. Sin, Claus F. Vogelmeier
Summary: Many patients with cardiovascular disease also suffer from chronic obstructive pulmonary disease (COPD), but COPD is often undiagnosed and untreated. It is important for cardiologists to recognize and treat COPD in patients with cardiovascular diseases because optimal COPD treatment can have significant benefits on cardiovascular outcomes. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) publishes annual reports that serve as clinical guidelines for COPD diagnosis and management worldwide, and the recently released 2023 report provides recommendations specifically relevant to cardiologists dealing with CVD patients who may have COPD.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Environmental Sciences
Ren Zhou, Shanliang Jin, Chenyu Jin, Yu Sun, Lei Zhang, Jia Yan, Hong Jiang
Summary: Studies have shown that exposure to bisphenol A (BPA) can lead to pulmonary diseases, but there is limited evidence on the association between urinary BPA level and COPD-related diseases. This study analyzed data from the National Health and Nutrition Examination Survey and found a significant association between urinary BPA and COPD-related diseases, particularly in males.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Kana Fujikura, Alessandra Albini, R. Graham Barr, Megha Parikh, Julia Kern, Eric Hoffman, Grant T. Hiura, David A. Bluemke, James Carr, Joao A. C. Lima, Erin D. Michos, Antoinette S. Gomes, Martin R. Prince
Summary: This study found that patients with COPD and severe emphysema had a larger aorta diameter. Compared to COPD related to chronic bronchitis or bronchial wall thickening, the dilation of aorta was more significant in these patients.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Computer Science, Artificial Intelligence
Xiaojin Zhang, Yan Kang, Kai Chen, Lixin Fan, Qiang Yang
Summary: This article introduces the requirements for privacy protection and model utility improvement in federated learning and proposes a unified federated learning framework. The article also presents the No-Free-Lunch theorem for the federated learning system, indicating that it is unrealistic to expect excellent privacy, utility, and efficiency simultaneously in certain scenarios. Additionally, the article analyzes the lower bounds of several widely-adopted protection mechanisms, providing guidance for selecting appropriate protection parameters.
ACM TRANSACTIONS ON INTELLIGENT SYSTEMS AND TECHNOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Yunus Colak, Borge G. Nordestgaard, Jorgen Vestbo, Shoaib Afzal, Peter Lange
Summary: Targeted spirometry in a general population setting can detect undiagnosed cases of COPD. A significant proportion of individuals with undiagnosed COPD also have other treatable conditions, such as smoking, respiratory symptoms, low physical activity, hypertension, hypercholesterolemia, and diabetes.
RESPIRATORY MEDICINE
(2022)
Article
Cell Biology
Sukesh Kumar Bajire, Rajesh P. Shastry
Summary: This article discusses the connection between COVID-19 and COPD, emphasizing the role of SARS-CoV-2 infection in severe COPD exacerbations. It provides a comprehensive overview of the subject matter, covering the pathogenesis, diagnosis, and therapy of COPD. The article highlights the need for a better understanding of the interaction between microbial infections, particularly with SARS-CoV-2, in order to effectively manage COPD.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2023)
Article
Computer Science, Artificial Intelligence
Qihong Wu, Jinchuan Tang, Shuping Dang, Gaojie Chen
Summary: In this article, the authors propose a privacy funnel based on mutual information to optimize the trade-off between user privacy and data utility in the era of big data and IoT. The proposed approach uses a mutual information neural estimator (MINE) to estimate mutual information, and optimizes the privacy utility trade-off through an encoding and decoding process. Simulations show that the designed framework has better performance and faster convergence compared to traditional methods.
EXPERT SYSTEMS WITH APPLICATIONS
(2022)
