Article
Medicine, General & Internal
Bronwyn Myers, Carl J. Lombard, Crick Lund, John A. Joska, Naomi Levitt, Tracey Naledi, Petal Petersen Williams, Claire van der Westhuizen, Pim Cuijpers, Dan J. Stein, Katherine R. Sorsdahl
Summary: This study compares the effectiveness of dedicated community health workers (CHWs), designated CHWs, and treatment as usual for patients with chronic physical diseases. The results showed that both the dedicated and designated groups had greater improvement in depression scores at 12 months, while reductions in alcohol use scores were similar across all groups. This study extends the evidence for CHW-delivered psychological interventions and provides insights into the effect of different delivery approaches on patient outcomes.
Article
Medicine, General & Internal
Giorgio Bosso, Mariarosaria De Luca, Giovanni Alma, Vincenzo Carbone, Ferdinando Ferrara, Biagio Fimiani, Franco Guarnaccia, Alessandro Iandolo, Sabato Murolo, Maurizio Olivares, Emanuele Romeo, Giosue Santoro, Antonio Valvano, Giovanni Zito, Ugo Oliviero
Summary: This study evaluated the adherence to guidelines-oriented dyslipidaemia's treatment in an outpatient population and found that optimizing therapies improved LDL-c levels in patients of different cardiovascular risks. The results showed a significant reduction in LDL-c in all risk categories at the end of the study, with an increase in the percentage of patients reaching lipid targets. It suggests carefully implementing measures to encourage outpatients and their cardiologists to achieve the targeted lipid profile according to cardiovascular risk.
INTERNAL AND EMERGENCY MEDICINE
(2022)
Article
Medicine, Research & Experimental
Federico Rea, Laura Savare, Giovanni Corrao, Giuseppe Mancia
Summary: Patients who were prescribed a single-pill combination of statin/ezetimibe were more likely to exhibit good adherence and less likely to have poor adherence to treatment compared to those prescribed a two-pill combination. This was associated with a decreased risk of cardiovascular events in patients with high adherence.
ADVANCES IN THERAPY
(2021)
Article
Medicine, General & Internal
Sun Hyoung Bae, Jung Jun Lee, Sun Young Son, Hee Young Kim, Man Ki Ju
Summary: This study aimed to investigate the correlations between health literacy, transplant effects, and compliance to treatment in organ transplant recipients and identify the factors influencing treatment compliance. The participants were organ transplant recipients visiting a transplantation center in Seoul, South Korea. The findings showed that health literacy, specifically actively managing one's health and social support for health, significantly affected treatment compliance. This highlights the importance of assessing patients' health literacy and providing tailored interventions to enhance patient outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Marjan Zakeri, Benjamin D. Lewing, Jennifer Contreras, Sujit S. Sansgiry
Summary: This study evaluated the impact of nonadherence to American Diabetes Association (ADA) guidelines on healthcare expenditures for patients with type 2 diabetes (T2D). Using retrospective cross-sectional cohort design and 2016-2018 Medical Expenditure Panel Survey data, patients diagnosed with T2D who completed the supplemental T2D care survey were included. The results showed that nonadherence to ADA guidelines led to a significant increase in healthcare expenditures, highlighting the importance of providing care based on ADA guidelines.
AMERICAN JOURNAL OF MANAGED CARE
(2023)
Review
Multidisciplinary Sciences
Ashok Kumar Das, Banshi Saboo, Anuj Maheshwari, V. Mohanan Nair, Samar Banerjee, C. Jayakumar, P. Benny, P. Sunil Prasobh, Anjana Ranjit Mohan, Vasudevan Sambu Potty, Jothydev Kesavadev
Summary: The Indian healthcare system faces challenges such as socioeconomic factors, insufficient medical resources, and economic disparities. This article proposes solutions and a model to address these issues.
Article
Oncology
Ronda Copher, Arianna Kee, Aaron Gerds
Summary: Myelofibrosis results in increased resource utilization and costs for patients and the US healthcare system. This study provides insights into treatment patterns, healthcare resource utilization, and costs associated with myelofibrosis, particularly in patients treated with ruxolitinib.
Review
Allergy
Melissa B. Gilkey, Wei Yi Kong, Kathryn L. Kennedy, Jennifer Heisler-MacKinnon, Elena Faugno, Barbara Gwinn, Ann Chen Wu, Ceila E. Loughlin, Alison A. Galbraith
Summary: Telemedicine has the potential to reduce the financial burden of asthma care, but it may also increase costs. The research highlights the importance of care coordination and communication in telemedicine.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2022)
Article
Medicine, General & Internal
Daniel A. Goldstein, Gary M. Ginsberg, Dorit Hofnung-Gabbay, Richard De Abreu Lourenco, Herbert H. Loong, Boon Cher Goh, Kelvin K. W. Chan, Massimo Di Maio, Francesco Perrone, Peter S. Hall, Alona Zer, Eli Rosenbaum
Summary: The US FDA has recently approved new dosing options for immune checkpoint inhibitors, including extended-interval fixed dosing. The economic impact of this new dosing strategy compared to the standard dosing strategy is unknown.
Review
Medicine, Research & Experimental
Amber Martin, Leona Bessonova, Rachel Hughes, Michael J. Doane, Amy K. O'Sullivan, Kassandra Snook, Allie Cichewicz, Peter J. Weiden, Philip D. Harvey
Summary: This study summarizes treatment patterns and associated costs related to oral antipsychotic treatment of patients with schizophrenia in the USA. The study found that suboptimal adherence, antipsychotic switching, and antipsychotic augmentation were all associated with high costs of care.
ADVANCES IN THERAPY
(2022)
Article
Multidisciplinary Sciences
Nelsensius Klau Fauk, Lillian Mwanri, Karen Hawke, Paul Russell Ward
Summary: This study highlights the barriers to access HIV care services among people living with HIV in Belu, including the use of traditional medicines and family and social influences.
Article
Multidisciplinary Sciences
Simiane Salete Volpi, Daiana Biduski, Ericles Andrei Bellei, Danieli Tefili, Lynn McCleary, Ana Luisa Sant'Anna Alves, Ana Carolina Bertoletti De Marchi
Summary: The study demonstrates that using an mHealth app can enhance patients' self-management of health and increase adherence to hypertension treatment, especially when the app provides a positive user experience.
Article
Otorhinolaryngology
Amanda Del Risco, Alex Cherches, Sherri L. Smith, Kristal M. Riska
Summary: This study retrospectively reviewed the charts of 458 patients diagnosed with benign paroxysmal positional vertigo (BPPV) in primary care. It found gaps in adherence to the 2017 AAO-HNS guidelines for the management and treatment of BPPV. However, these gaps did not differ by sex, race, or insurance status.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Health Care Sciences & Services
Beatriz Navarro-Brazalez, Fernando Vergara-Perez, Virginia Prieto-Gomez, Beatriz Sanchez-Sanchez, Maria Jose Yuste-Sanchez, Maria Torres-Lacomba
Summary: In the conservative treatment of pelvic floor dysfunction, patients' adherence to home exercises is influenced by factors such as the nature of the exercise program, its efficacy, personal experiences, intrinsic factors like self-awareness and beliefs, and external factors like professional feedback. Effective physiotherapy programs that include agreed-upon home exercises and simple movements can help improve patient adherence.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Letter
Medicine, General & Internal
Suveen Angraal, Arun George Zachariah, Raaisa Raaisa, Rohan Khera, Praveen Rao, Harlan M. Krumholz, John A. Spertus
Summary: This study investigates online crowdsourced fundraising for US health care costs from 2010 to 2018, examining trends by medical condition and geographic distribution.
Article
Pharmacology & Pharmacy
Sylvie Perreault, Alice Dragomir, Robert Cote, Aurelie Lenglet, Simon de Denus, Marc Dorais, Brian White-Guay, James Brophy, Mireille E. Schnitzer, Marie-Pierre Dube, Jean-Claude Tardif
Summary: This study compares the effectiveness and safety of different doses of direct oral anticoagulants (DOACs) with warfarin or other DOACs for patients with atrial fibrillation (AF). The results show that low-dose dabigatran has better effectiveness but worse safety compared to warfarin, while low-dose apixaban has better safety than warfarin.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Psychiatry
Veronique Bouchard, Annie Robitaille, Sylvie Perreault, Marie-Christyne Cyr, Jean -Claude Tardif, David Busseuil, Bianca D'Antono
Summary: This study examined the impact of psychological distress on outpatient care utilization in patients with coronary artery disease (CAD). The results showed a significant correlation between depressive symptoms and outpatient care utilization, particularly in CAD patients. Further research is needed to determine whether psychosocial interventions can have an impact on healthcare utilization.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Multidisciplinary Sciences
Sylvie Perreault, Robert Cote, Alice Dragomir, Brian White-Guay, Aurelie Lenglet, Marc Dorais
Summary: There was no significant difference in the effectiveness or safety outcome between low-dose and standard-dose rivaroxaban in patients with atrial fibrillation. However, low-dose apixaban was associated with a greater risk of stroke/systemic embolism and death without a reduction in bleeding rates.
Article
Multidisciplinary Sciences
Sylvie Perreault, Mireille E. Schnitzer, Eliane Disso, Jakub Qazi, Laurie-Anne Boivin-Proulx, Marc Dorais
Summary: Polypharmacy is associated with increased mortality risk in patients with heart failure, while cardiovascular and non-cardiovascular polypharmacy do not show significant associations. Certain heart conditions and health problems are associated with increased mortality risk, while the use of certain medications can lower the risk.
SCIENTIFIC REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Laurie-Anne Boivin-Proulx, Brian J. Potter, Marc Dorais, Sylvie Perreault
Summary: This study investigated the changes in antithrombotic medication prescription patterns among patients with atrial fibrillation undergoing percutaneous coronary intervention. The results showed that the publication of guidelines in 2016 had a positive impact on the prescription of oral anticoagulation therapy. However, a substantial treatment gap still existed even after the guidelines were published.
Article
Oncology
Alice Dragomir, Nawar Touma, Jason Hu, Sylvie Perreault, Armen G. Aprikian
Summary: This study evaluated the risk of cardiovascular disease (CVD) associated with gonadotropin-releasing hormone (GnRH) agonists versus GnRH antagonist in patients with prostate cancer. The results showed that the use of GnRH antagonist decreased the risk of heart failure in patients with prior CVD, and decreased the risk of ischemic heart disease in patients without prior CVD but increased the risk of arrhythmia.
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK
(2023)
Article
Cardiac & Cardiovascular Systems
Rahul Aggarwal, Christian T. Ruff, Saverio Virdone, Sylvie Perreault, Ajay K. Kakkar, Michael G. Palazzolo, Marc Dorais, Gloria Kayani, Daniel E. Singer, Eric Secemsky, Jonathan Piccini, Usman A. Tahir, Changyu Shen, Robert W. Yeh
Summary: A clinical risk score was developed and validated to personalize bleeding risk assessment for individuals with atrial fibrillation taking direct-acting oral anticoagulants (DOACs). The risk score showed superior performance compared to existing clinical decision tools and can help stratify patients based on their expected bleeding risk.
Meeting Abstract
Cardiac & Cardiovascular Systems
Laurie-Anne Boivin Proulx, Marc Dorais, Sylvie Perreault
Meeting Abstract
Cardiac & Cardiovascular Systems
Laurie-Anne Boivin Proulx, Aurelie Langlet, Catherine Legault, Marc Dorais, Sylvie Perreault
Meeting Abstract
Cardiac & Cardiovascular Systems
Laurie-Anne Boivin Proulx, Aurelie Langlet, Marc Dorais, Sylvie Perreault
Meeting Abstract
Cardiac & Cardiovascular Systems
Laurie-Anne Boivin Proulx, Brian J. Potter, Sylvie Perreault
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Laurie-Anne Boivin-Proulx, Brian J. Potter, Marc Dorais, Sylvie Perreault
Summary: Obese patients are often excluded from clinical trials comparing the effectiveness and safety of direct oral anticoagulants in atrial fibrillation patients. However, this study found that the use of direct oral anticoagulants in obese atrial fibrillation patients showed similar effectiveness and safety compared to warfarin use.
Meeting Abstract
Economics
S. Perreault, M. Schnitzer, E. Disso, J. Qazi, M. Dorais
Meeting Abstract
Economics
S. Perreault, A. Dragomir, A. Lenglet, M. Dorais
Meeting Abstract
Economics
A. Lenglet, J. Qazi, M. Dorais, S. Perreault