期刊
VACCINE
卷 32, 期 15, 页码 1768-1773出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2013.11.107
关键词
Japanese encephalitis; Live attenuated vaccine; Safety; Adverse event following immunization
We reviewed the adverse events following immunization of live attenuated Japanese encephalitis vaccine in Guangdong Province, China. During the period of 2005-2012, 23 million doses of live attenuated Japanese encephalitis vaccine were used and 1426 adverse events were reported (61.24 per million doses); of which, 570 (40%) were classified as allergic reactions (24.48 per million doses), 31 (2%) were neurologic events (1.33 per million doses), and 36(2.5%) were diagnosed as serious adverse events (1.55 per million doses). This study suggests that the JEV-L has a reasonable safety profile, most adverse events are relatively mild, with relatively rare neurologic events being observed. (C) 2014 Elsevier Ltd. All rights reserved.
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