期刊
VACCINE
卷 28, 期 45, 页码 7273-7278出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2010.08.085
关键词
Hepatitis C virus; Vaccine; People who inject drugs
资金
- National Health and Medical Research Council (NHMRC) [630483]
- Michael Smith Foundation for Health Research
- Canadian Institutes for Health Research
- U.S. National Institutes for Health (NIH) [2 R01 DA016017-03A1, 5 U19 AI40034-13]
- Australian Government Department of Health and Ageing
People who inject drugs (PWID) are at high risk of HCV. Limited evidence of the effectiveness of prevention interventions and low uptake of treatment in this group highlight the need for increased investment in biomedical interventions, notably safe and efficacious vaccines. While several candidates are currently in development, field trials in PWID present challenges, including ethical issues associated with trial literacy, informed consent and standards of care. Significant biological and social factors and differences between HIV and HCV suggest that HCV warrants targeted vaccine preparedness research to lay the groundwork for successful implementation of future trials. (C) 2010 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据