期刊
UROLOGE
卷 48, 期 11, 页码 1346-1351出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00120-009-2086-1
关键词
Propiverine ER; Non-interventional study; Overactive bladder; Urge urinary incontinence
Background. The aim of this non-interventional study was to evaluate the efficacy and tolerability of propiverine ER under real life conditions. Patients and methods. The treatment of 5,565 patients with urge urinary incontinence, urgency or mixed urinary incontinence was documented over a 12-week period. Incontinence episodes, voiding frequency and voided volume were recorded at 3 visits (admission, after 4 and 12 weeks). Additionally the tolerability was evaluated at visits 2 and 3. Results. The average incontinence episodes/24 h decreased during therapy from 4.23 to 2.89. The frequency of micturitions/24 h decreased by 5.50. The voided volume improved by 69 ml. Approximately 92 % of investigators and patients assessed the efficacy similarly with very good and good. Dry mouth was the most frequent adverse drug reaction and decreased from 16.5 % after 4 weeks to 13.6 % after 12 weeks of treatment. Conclusion. The efficacy and tolerability of propiverine ER were confirmed under real life conditions.
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