Article
Nanoscience & Nanotechnology
Chao Jiang, Lingfeng He, Cody A. Dennett, Marat Khafizov, J. Matthew Mann, David H. Hurley
Summary: We demonstrate the use of ab initio basin-hopping simulations in synergy with object kinetic Monte Carlo simulations as a powerful tool for identifying small defect complexes in irradiated materials. Our study reveals an unexpected role of bound anti-Schottky defect clusters in mediating defect transport.
SCRIPTA MATERIALIA
(2022)
Article
Microscopy
C. Gao, C. Hofer, T. J. Pennycook
Summary: Ptychography provides high dose efficiency images that can reveal light elements next to heavy atoms. However, contrast reversals can occur when the projected potential becomes strong. Recent research has shown that these reversals can be counteracted by adapting the focus. This study explains why the best contrast is often found with the probe focused to the middle of the sample and highlights the importance of convergence angle in thin samples to remove contrast reversals.
Article
Chemistry, Multidisciplinary
Ze Zhang, Joel Martis, Xintong Xu, Hao-Kun Li, Chenlu Xie, Brad Takasuka, Jonghoon Lee, Ajit K. Roy, Arun Majumdar
Summary: Photoabsorption microscopy using electron analysis achieves high-resolution spectrally specific photoabsorption imaging, offering a general approach for nanometer-scale optical spectroscopic imaging and material characterization.
Article
Polymer Science
Botao Hao, Zhiyuan Ding, Xudong Tao, Peter D. Nellist, Hazel E. Assender
Summary: Polyvinyl alcohol (PVA) is a promising material in medical and packaging applications due to its biocompatibility, water solubility, low density, and cost-effectiveness. This study uses electron ptychography to image the crystallinity of PVA, revealing deviations from previous models derived from X-ray diffraction. A new model is proposed based on these findings, and simulated results confirm its accuracy. The ability to directly image molecular order in PVA crystals opens up new opportunities for research in this field.
Article
Cell Biology
Kiranjit K. Bains, Robert D. Young, Elena Koudouna, Philip N. Lewis, Andrew J. Quantock
Summary: Imaging techniques were used to study the three-dimensional microanatomy and spatiotemporal relationships of cells, extracellular matrix, and vasculature at the corneo-scleral limbus of developing and mature chicken eyes. Results showed the development of structures similar to Palisades of Vogt, associated with characteristics of stem cells, and direct cell-cell associations between corneal epithelial and stromal cells.
Article
Nanoscience & Nanotechnology
T. W. J. Kwok, T. P. McAuliffe, A. K. Ackerman, B. H. Savitzky, M. Danaie, C. Ophus, D. Dye
Summary: A TWIP steel with a specific composition was deformed to 6% strain and analyzed using 4D-STEM technique. It was found that the average elastic strain parallel and perpendicular to the twinning direction was about 6%, but there were hot spots with even larger strains up to 12%. These hot spots were attributed to a high density of Frank dislocations on the twin boundary. The strain fields in the TWIP steel were significantly larger than other twinning materials, and could explain the early thickness saturation of nanotwins.
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2023)
Article
Chemistry, Multidisciplinary
Ivo Konvalina, Ales Patak, Martin Zouhar, Ilona Muellerova, Tomas Fort, Marek Uncovsky, Eliska Materna Mikmekova
Summary: This paper introduces the use of segmented semiconductor detectors in ultrahigh resolution scanning electron microscopes and studies the capability of the detector and quantification of measured images. A new method is proposed to enable better comparison between measured and simulated data through additional measurements, called calibration curves. The measurements acquired using a 2D pixel array detector are also analyzed. The comparison between experimental and simulation data can help estimate the composition or thickness of the sample.
Article
Chemistry, Multidisciplinary
Xu Zhang, Xiang Zhang, Pulickel M. Ajayan, Jianguo Wen, Horacio D. Espinosa
Summary: The annihilation of vacancy clusters in monolayer molybdenum diselenide (MoSe2) under electron beam irradiation is achieved by diffusion of vacancies towards the free edge. It is shown that electron beam irradiation and pre-stress in the suspended MoSe2 monolayer are necessary for vacancies to overcome energy barriers for diffusion. This new mechanism of vacancy healing in 2D materials expands the capability of electron beam in defect engineering and tuning the properties of 2D materials for applications.
Article
Multidisciplinary Sciences
Koji Inoue, Kenta Yoshida, Yasuyoshi Nagai, Kyosuke Kishida, Haruyuki Inui
Summary: APT and TEM/STEM were used correlatively to explore the atomic-scale local structure and chemistry changes during the growth of the LPSO phase in Mg-Al-Gd alloy. It was discovered that enrichment of Gd atoms precedes that of Al atoms, and the formation of Al6Gd8 clusters requires sufficient diffusion of Al atoms into the relevant portions. Lateral growth of the LPSO phase is believed to occur through a 'ledge' mechanism controlled by diffusion of Al atoms.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Physical
Muhammad Ali, Fuzhou Han, Wenbin Guo, Jie Ren, Yingdong Zhang, Fusen Yuan, Qichen Wang, Jianan Hu, Chengze Liu, Hengfei Gu, Geping Li
Summary: Fractured C14 (hexagonal close-packed) Laves phase Zr(Fe,Cr)2 precipitates were observed in beta forged Zircaloy4. The fractures mainly occurred along the c-axes of Laves phase precipitates. The narrow interfacial width and small misorientation angle suggested the retention of brittle nature at high temperature.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Chemistry, Physical
Qiang Yang, Xiaohan Wu, Wei Zhang, Zixaing Yan, Guodong Tong, Xuegang Chen, Shuhui Lv, Tao Xu, Jun Li, Xin Qiu
Summary: An ultrathin wall Mg-8Zn-8Al alloy with coarse ix-Mg grains, ultra-fine beta-Mg grains, and nano-sized icosahedral quasicrystal phase particles has been manufactured by high-pressure die casting. The alloy exhibits outstanding strength and acceptable elongation. The observations through HAADF-STEM reveal possible amorphous regions, C-containing phase and/or MgO aggregations, and Zn-rich clusters and pyramidal precipitates. The combination of ultra-fine grains and the skeleton consisting of nano-sized I-phase particles and solutes contributes to the ultra-high strength. In addition, the study indicates the unavoidable interaction of alloy melt with CO2 during ultra-thin wall HPDC and the possibility of pyramidal precipitation in Zn-containing magnesium alloys.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Food Science & Technology
Amal S. Albedwawi, Reem Al Sakkaf, Tareq M. Osaili, Ahmed Yusuf, Amin Olaimat, Shao-Quan Liu, Giovanni Palmisano, Nagendra P. Shah, Mutamed M. Ayyash
Summary: This paper investigated the ability of lactic acid bacteria (LAB) and Bifidobacterium to remove acrylamide (AA) and examined the mechanism(s) of the AA removal using various microscopic techniques. The results showed that Bifidobacterium breve and Lactiplantibacillus plantarum exhibited higher acrylamide reduction rates. The study also found that both strains could tolerate low pH levels and remove acrylamide under in vitro gastrointestinal conditions.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Yaowei Hu, Matthieu Picher, Marlene Palluel, Nathalie Daro, Eric Freysz, Laurentiu Stoleriu, Cristian Enachescu, Guillaume Chastanet, Florian Banhart
Summary: The unusual expansion dynamics of individual spin crossover nanoparticles were investigated using ultrafast transmission electron microscopy. Upon exposure to nanosecond laser pulses, the particles exhibited significant length oscillations during and after expansion. The observed oscillation period of 50-100 ns was similar to the time required for the particles to transition between low-spin and high-spin states. Monte Carlo calculations incorporating elastic and thermal coupling between molecules within a crystalline spin crossover particle were able to explain the observed length oscillations. The system underwent repeated transitions between the two spin states until relaxation in the high-spin state occurred due to energy dissipation.
Article
Nanoscience & Nanotechnology
Yawei Li, Li Wang, Yufeng He, Wei Zheng, Langhong Lou, Jian Zhang
Summary: The study found that as the temperature increases, the spacing of dislocation networks in the gamma/gamma' interface decreases, while the minimum creep rate increases non-linearly. This is due to the enhanced dislocation-climb in the interface and gamma'-cutting by a <010> superdislocations.
SCRIPTA MATERIALIA
(2022)
Article
Materials Science, Multidisciplinary
Ryan B. Sills, Douglas L. Medlin
Summary: The characterization of the three-dimensional arrangement of dislocations is important for many analyses in materials science. This paper presents a semi-automated object-based approach that reduces data collection requirements by utilizing the prior knowledge that dislocations are line objects.
MICROSCOPY AND MICROANALYSIS
(2022)
Article
Biochemistry & Molecular Biology
E. L. McBride, A. Rao, G. Zhang, J. D. Hoyne, G. N. Calco, B. C. Kuo, Q. He, A. A. Prince, I. D. Pokrovskaya, B. Storrie, A. A. Sousa, M. A. Aronova, R. D. Leapman
JOURNAL OF STRUCTURAL BIOLOGY
(2018)
Article
Chemistry, Multidisciplinary
Andre L. Lira, Rodrigo S. Ferreira, Ricardo J. S. Torquato, Huaying Zhao, Maria Luiza V. Oliva, Sergio A. Hassan, Peter Schuck, Alioscka A. Sousa
Article
Anatomy & Morphology
Xiaobing Chen, Christine Winters, Virginia Crocker, Michael Lazarou, Alioscka A. Sousa, Richard D. Leapman, Thomas S. Reese
FRONTIERS IN NEUROANATOMY
(2018)
Article
Chemistry, Physical
Rodrigo S. Ferreira, Andre L. Lira, Ricardo J. S. Torquato, Peter Schuck, Alioscka A. Sousa
JOURNAL OF PHYSICAL CHEMISTRY C
(2019)
Article
Chemistry, Physical
Luiza L. Knittel, Huaying Zhao, Ai Nguyen, Antonio Miranda, Peter Schuck, Alioscka A. Sousa
JOURNAL OF PHYSICAL CHEMISTRY B
(2020)
Article
Chemistry, Multidisciplinary
Andre L. Lira, Rodrigo S. Ferreira, Maria Luiza Oliva, Alioscka A. Sousa
Article
Cell Biology
John P. McCauley, Maurice A. Petroccione, Lianna Y. D'Brant, Gabrielle C. Todd, Nurat Affinnih, Justin J. Wisnoski, Shergil Zahid, Swasti Shree, Alioscka A. Sousa, Rose M. De Guzman, Rosanna Migliore, Alexey Brazhe, Richard D. Leapman, Alexander Khmaladze, Alexey Semyanov, Damian G. Zuloaga, Michele Migliore, Annalisa Scimemi
Article
Chemistry, Medicinal
Andre L. Lira, Natasha Mina, Camila R. Bonturi, Ruben S. Nogueira, Ricardo J. S. Torquato, Maria Luiza V. Oliva, Alioscka A. Sousa
Summary: Ultrasmall gold nanoparticles (usNPs) and nanoclusters are a type of emerging nanomaterials with unique physicochemical properties and in vivo behaviors. This study found that anionic usNPs can bind to and activate factor XII (FXII), leading to the promotion of coagulation cascade. This suggests that anionic usNPs may disrupt the normal hemostatic balance.
CHEMICAL RESEARCH IN TOXICOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Andre F. Lima, Vinicius S. Guido, Natasha Mina, Ricardo J. S. Torquato, Alioscka A. Sousa
Summary: This study investigated the interactions between ultrasmall gold nanoparticles (usGNPs) and six different proteins. The results showed that prolonged interactions between proteins and usGNPs permanently altered protein function, while both short and long-term interactions yielded short-lived complexes. This study enhances our understanding of nano-bio interactions in the ultrasmall size regime.
Article
Chemistry, Multidisciplinary
Paulo H. Jr Jr Olivieri, Marcelo B. Jesus, Helena B. Nader, Giselle Z. Justo, Alioscka A. Sousa
Summary: This study reveals that surface glycosaminoglycans (GAGs) can regulate the cellular internalization of nanoparticles. Anionic nanoparticles are hindered by the charged surface GAGs, while cationic nanoparticles interact favorably with GAGs. Further investigation shows that the interaction of nanoparticles with GAGs is different, and heparan sulfate plays a crucial role in the cellular internalization of cationic nanoparticles.
Review
Chemistry, Multidisciplinary
Alioscka A. Sousa, Peter Schuck, Sergio A. Hassan
Summary: The use of nanoparticles in biomedicine has transitioned from concept to clinical trials, with ultrasmall nanoparticles showing potential applications in diagnosis and therapy. The ability to control the behavior of these nanoparticles is limited, and further advances are needed in nanoengineering and chemical synthesis to fully understand their interactions in biological environments.
NANOSCALE ADVANCES
(2021)
Article
Chemistry, Multidisciplinary
Rodrigo S. Ferreira, Andre L. Lira, Alioscka A. Sousa
Article
Chemistry, Multidisciplinary
Alioscka A. Sousa
Article
Chemistry, Multidisciplinary
Andre L. Lira, Rodrigo S. Ferreira, Ricardo J. S. Torquato, Maria Luiza Oliva, Peter Schuck, Alioscka A. Sousa
NANOSCALE ADVANCES
(2019)
Proceedings Paper
Engineering, Biomedical
Matthew Guay, Zeyad Emam, Adam Anderson, Richard Leapman
2018 IEEE 15TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI 2018)
(2018)
Article
Microscopy
C. Gao, C. Hofer, T. J. Pennycook
Summary: Ptychography provides high dose efficiency images that can reveal light elements next to heavy atoms. However, contrast reversals can occur when the projected potential becomes strong. Recent research has shown that these reversals can be counteracted by adapting the focus. This study explains why the best contrast is often found with the probe focused to the middle of the sample and highlights the importance of convergence angle in thin samples to remove contrast reversals.
Article
Microscopy
J. Lindner, U. Ross, T. Meyer, V. Boureau, M. Seibt, Ch. Jooss
Summary: Phase-shifting electron holography is an excellent method with high phase sensitivity to reveal electron wave phase information. An advanced drift correction scheme is proposed in this study, which exploits the interface of the TEM specimen and the vacuum area in the hologram. This method allows for obtaining reliable phase information.
Article
Microscopy
Ali Jaberi, Nicolas Brodusch, Jun Song, Raynald Gauvin
Summary: This study investigates knock-on damage in lithium-ion batteries (LIBs) by computing threshold displacement energies (TDEs) and performing Monte Carlo simulation. The results indicate that Li is most sensitive to knock-on damage at moderate electron energies, and TDE is the principal parameter for assessing Li sensitivity to knock-on damage across similar structures.
Article
Microscopy
Alexander Schroeder, Christopher Rathje, Leon van Velzen, Maurits Kelder, Sascha Schaefer
Summary: This study utilizes novel event-based electron detector platforms to extend the temporal resolution of electron microscopy. By training a neural network to predict electron arrival time, the researchers were able to improve the timing accuracy and achieve a promising solution for enhancing electron timing precision in various electron microscopy applications.
Article
Microscopy
Avi Auslender, Nivedita Pandey, Amit Kohn, Oswaldo Dieguez
Summary: This article describes a faster implementation based on DFT for computing the mean inner potential of crystals, providing quantum-mechanical calculations beyond the independent-atom approximation. The study also reveals the dependence of the mean inner potential on sample boundary conditions, mass density, and magnetic susceptibility, highlighting its correlation with various material properties.
Article
Microscopy
Zhidong Yang, Dawei Zang, Hongjia Li, Zhao Zhang, Fa Zhang, Renmin Han
Summary: In this work, we propose a self-supervised deep learning model for cryo-ET volumetric image denoising based on noise modeling and sparsity guidance. Experimental results demonstrate that our method can achieve reliable denoising by training on single noisy volume and outperform existing methods.
Article
Microscopy
J. Kuttruff, J. Holder, Y. Meng, P. Baum
Summary: In this study, a robust clustering algorithm is proposed that can find clusters in a continuous stream of raw data in real time. This algorithm converts pixel hits measured by hybrid pixel detectors to real single-electron events. By continuously comparing with previous hits, the algorithm efficiently identifies the merging of new and old events.
Article
Microscopy
D. G. Senturk, C. P. Yu, A. De Backer, S. Van Aert
Summary: This article presents a statistics-based method for accurately counting the number of atoms in nanostructures, especially for images acquired with low electron doses and multiple element structures.
Article
Microscopy
Mauricio J. Prieto, Lucas de Souza Caldas, Liviu C. Tanase, Thomas Schmidt, Oscar Rodriguez de la Fuente
Summary: This study presents a synchrotron-based investigation of the synthesis process of a magnetite/hematite bilayer. Ion bombardment gradually transforms hematite into magnetite, and the growth of magnetite leads to the formation of stable boundaries. These findings are significant for understanding novel oxide heterostructures.
Article
Microscopy
Emre Yoruk, Holger Klein, Stephanie Kodjikian
Summary: Beam sensitive nanomaterials pose challenges for crystallographic structure determination. A dose symmetric electron diffraction tomography (DS-EDT) method is developed to reduce beam damage and obtain complete data sets by merging individual datasets from multiple crystals.
Article
Microscopy
A. Pofelski, Y. Zhu, G. A. Botton
Summary: The precision and sensitivity of the GPA method for strain characterization is a widely discussed topic. This study introduces the concept of phase noise and analyzes the parameter of sampling to improve the precision of GPA. Experimental and theoretical results demonstrate that using a larger pixel spacing in STEM can enhance the precision and sensitivity of the GPA method.
Article
Microscopy
Sangjun Kang, Di Wang, Christian Kuebel, Xiaoke Mu
Summary: Transmission electron microscopy is a valuable tool for assessing strain fields within materials. However, using thin specimens in TEM analysis can affect atomic configuration and deformation structure.
