Article
Endocrinology & Metabolism
In-Ho Jung, Seonah Choi, Cheol Ryong Ku, Sang-Guk Lee, Eun Jig Lee, Sun Ho Kim, Eui Hyun Kim
Summary: This study evaluated the reliability of IGF-1 levels as an alternative for disease monitoring after surgical treatment of acromegaly. The results showed that IGF-1 levels can serve as a reliable alternative to OGTT and play a valuable role in monitoring acromegaly status.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Review
Endocrinology & Metabolism
Mengyang Li
Summary: The GH/IGF system plays a role in growth regulation in the body. By studying the basal chordate amphioxus, it was discovered that most members of the GH/IGF system are present in amphioxus, providing strong evidence for the origin of this system in amphioxus.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Yang Xu, Chang Yong Han, Mi Jung Park, Myung Chan Gye
Summary: This study investigated the mechanism of precocious sexual maturation following prepubertal rhGH therapy. The results showed that rhGH can promote gonadal maturation by activating the steroidogenic pathway of LCs and increasing testicular IGF1 levels.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2022)
Article
Psychiatry
Naomichi Okamoto, Koji Yoshino, Shogo Kitagawa, Rintaro Fujii, Shinsuke Hamada, Atsuko Ikenouchi, Yuki Konishi, Nobuhisa Ueda, Yoshinori Eto, Yasunari Tsutsumi, Reiji Yoshimura
Summary: This study found no significant difference in serum IGF-1 levels between patients with chronic schizophrenia and healthy controls. Serum IGF-1 levels were significantly negatively correlated with PANSS total and general scores, and were associated with patient age.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Medicine, General & Internal
Layla Damen, Melitza S. M. Elizabeth, Stephany H. Donze, Sjoerd A. A. van den Berg, Laura C. G. de Graaff, Anita C. S. Hokken-Koelega
Summary: In children with Prader-Willi syndrome receiving GH treatment, high immunoreactive IGF-I levels are often observed, while free IGF-I levels are low, indicating a significant discrepancy between the two.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Genetics & Heredity
Rui-Lin Xie, Rui Liang, Yuan-Yuan Luo, Zhuo-Hao Ruan, Yi-Fu Li, Wen-Sheng Liu
Summary: This study investigates the effects of growth hormone changes on the genes and regulatory roles of the turtle. The results show that the injection of recombinant human growth hormone promotes the growth of the turtle by affecting the expression of SS, GHR, and IGF-1 genes.
Review
Endocrinology & Metabolism
Laura E. Dichtel, Jose Cordoba-Chacon, Rhonda D. Kineman
Summary: This article summarizes the high prevalence of nonalcoholic fatty liver disease (NAFLD) in patients with obesity and its progression to nonalcoholic steatohepatitis (NASH). Understanding the etiology of NAFLD is clinically relevant as it is an independent risk factor for diabetes and cardiovascular disease. The potential role of growth hormone and insulin-like growth factor 1 in regulating hepatic steatosis, inflammation, and fibrosis is discussed.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Dermatology
Yesim Akpinar Kara
Summary: The study revealed that acne severity and serum IGF-1 levels are significantly higher in patients under the age of 21 compared to patients over the age of 21. However, there was no significant difference in the serum IGF-1, insulin, and glucose levels between the acne group and the control group.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Endocrinology & Metabolism
Christa C. van Bunderen, Rick I. Meijer, Paul Lips, Mark H. Kramer, Erik H. Serne, Madeleine L. Drent
Summary: The study found that increasing IGF-1 levels had a beneficial effect on body composition but was detrimental to insulin resistance. At the same time, the contribution of the neurogenic vasomotion domain also increased.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Chemistry, Medicinal
Fatemeh Meshkini, Nahid Ramezani-Jolfaie, Saman Sargazi, Cain C. T. Clark, Sepideh Soltani
Summary: A systematic review of the effects of lycopene on circulating IGF-1 and IGFBPs in adults found no consistent modifying effect of lycopene supplementation on IGF-1 and IGFBP levels. More research is needed to explore the effect of lycopene on the IGF-1 system.
PHYTOTHERAPY RESEARCH
(2022)
Article
Endocrinology & Metabolism
Ioannis Ilias, Aristidis Diamantopoulos, Efthymia Botoula, Nikolaos Athanasiou, Alexandros Zacharis, Stamatios Tsipilis, Edison Jahaj, Alice G. Vassiliou, Dimitra A. Vassiliadi, Anastasia Kotanidou, Stylianos Tsagarakis, Ioanna Dimopoulou
Summary: The study aimed to measure IGF1 and GH in critically and non-critically ill Covid-19 patients. Results showed that IGF-1 levels were higher in survivors compared to non-survivors, suggesting a potential association between low IGF1 and poor outcomes in Covid-19 patients.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Yoshifumi Horie, Kensuke Mitsunaga, Chee Kong Yap
Summary: Pyriproxyfen, an agricultural pesticide, was found to have a lethal effect on zebrafish in a concentration-dependent manner. The study also revealed that pyriproxyfen disrupts thyroid hormone activity in zebrafish and inhibits their growth by suppressing the expression of growth hormone.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Qian Xin, Victoria Anthony Uyanga, Hongchao Jiao, Jingpeng Zhao, Xiaojuan Wang, Haifang Li, Yunlei Zhou, Hai Lin
Summary: The decrease in serum and follicular IGF1 concentration is associated with the reduced egg production of aged laying hens. This study provides novel insights into the endocrine changes in aged hens with different egg production rates.
JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Kangkang Chen, Xiaoyi Dou, Jai Hoon Eum, Ruby E. Harrison, Mark R. Brown, Michael R. Strand
Summary: This study assessed the expression of insulin-like peptides (ILPs) and ovary ecdysteroidogenic hormone (OEH) in Aedes aegypti during a gonadotrophic cycle and further functionally characterized these peptides to understand their roles in regulating egg formation. The results showed that all ILPs and OEH were expressed during the cycle, and there were differences in their biological activities and insulin- insulin growth factor signaling (IIS) phosphorylation levels.
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2023)
Article
Medical Laboratory Technology
Jason K. Y. Lee, Kendall Cradic, Ravinder J. Singh, JoAnna Jones, Jieli Li
Summary: This study compared the measurement of IGF-1 on four different platforms and found significant variations between them. These variations should be considered when managing patients with pituitary disorders.
CLINICA CHIMICA ACTA
(2023)