HIFs enhance the migratory and neoplastic capacities of hepatocellular carcinoma cells by promoting EMT

Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion

(2013) Hildegonda P.H. Naber et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma

(2013) Lin Zhang et al.   BMC CANCER

MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways

(2013) Longlong Bao et al.   CANCER LETTERS

HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression

(2013) B. Philip et al.   CARCINOGENESIS

Wnt/β-catenin signaling enhances hypoxia-induced epithelial–mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling

(2013) Qi Zhang et al.   CARCINOGENESIS

Slug promoted vasculogenic mimicry in hepatocellular carcinoma

(2013) Dan Sun et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

HIF1α and HIF2α independently activate SRC to promote melanoma metastases

(2013) Sara C. Hanna et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibitions of epithelial to mesenchymal transition and cancer stem cells-like properties are involved in miR-148a-mediated anti-metastasis of hepatocellular carcinoma

(2013) Han Yan et al.   MOLECULAR CARCINOGENESIS

Claudin-1 as a promoter of EMT in hepatocellular carcinoma

(2013) J Stebbing et al.   ONCOGENE

Blockade of p53 by HIF-2α, but not HIF-1α, is involved in arsenite-induced malignant transformation of human bronchial epithelial cells

(2012) Yuan Xu et al.   ARCHIVES OF TOXICOLOGY

Sonic hedgehog signaling pathway induces cell migration and invasion through focal adhesion kinase/AKT signaling-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 in liver cancer

(2012) Jing-Song Chen et al.   CARCINOGENESIS

Overexpression of macrophage migration inhibitory factor in adenoid cystic carcinoma: correlation with enhanced metastatic potential

(2012) Hui Liu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

EMT and Stem Cell-Like Properties Associated with HIF-2α Are Involved in Arsenite-Induced Transformation of Human Bronchial Epithelial Cells

(2012) Yuan Xu et al.   PLoS One

The accumulations of HIF-1α and HIF-2α by JNK and ERK are involved in biphasic effects induced by different levels of arsenite in human bronchial epithelial cells

(2012) Yuan Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

EMT: A new vision of hypoxia promoting cancer progression

(2011) Jian Jiang et al.   CANCER BIOLOGY & THERAPY

Matrix metalloproteinase-9 cooperates with transcription factor Snail to induce epithelial-mesenchymal transition

(2011) Chun-Yu Lin et al.   CANCER SCIENCE

Therapeutic and prognostic importance of epithelial–mesenchymal transition in liver cancers: Insights from experimental models

(2011) Olorunseun O. Ogunwobi et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma

(2011) Xiao Qi Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells

(2011) Mingli Han et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The expression of HIF-1α in primary hepatocellular carcinoma and its correlation with radiotherapy response and clinical outcome

(2011) Zuo-Lin Xiang et al.   MOLECULAR BIOLOGY REPORTS

Promotion of hepatocellular carcinoma metastasis through matrix metalloproteinase activation by epithelial-mesenchymal transition regulator Twist1

(2010) Xiu-lan Zhao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hepatocellular Carcinoma: Consensus Recommendations of the National Cancer Institute Clinical Trials Planning Meeting

(2010) Melanie B. Thomas et al.   JOURNAL OF CLINICAL ONCOLOGY

Hypoxia-inducible factor-1 alpha, in association with inflammation, angiogenesis and MYC, is a critical prognostic factor in patients with HCC after surgery

(2009) Chen-Xin Dai et al.   BMC CANCER

HIF-1α mediates the induction of IL-8 and VEGF expression on infection with Afa/Dr diffusely adheringE. coliand promotes EMT-like behaviour

(2009) Gaëlle Cane et al.   CELLULAR MICROBIOLOGY

Epithelial–mesenchymal transition in hepatocellular carcinoma

(2009) Franziska van Zijl et al.   Future Oncology

Hyperoxic Treatment Induces Mesenchymal-to-Epithelial Transition in a Rat Adenocarcinoma Model

(2009) Ingrid Moen et al.   PLoS One