4.3 Article

A decade of Japanese encephalities surveillance in Sarawak, Malaysia: 1997-2006

期刊

TROPICAL MEDICINE & INTERNATIONAL HEALTH
卷 13, 期 1, 页码 52-55

出版社

BLACKWELL PUBLISHING
DOI: 10.1111/j.1365-3156.2007.01967.x

关键词

Japanese encephalitis; surveillance; vaccine

资金

  1. Wellcome Trust [076330] Funding Source: Medline

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Japanese encephalitis virus (JEV) is an important encephalitis virus in Asia, but there are few data on Malaysia. A hospital-based surveillance system for Japanese encephalitis (JE) has been in operation in Sarawak, Malaysia, for the last 10 years. JEV is endemic in Sarawak, with cases occurring throughout the year and a seasonal peak in the last quarter (one-way ANOVA, P < 0.0001). Ninety-two per cent of 133 cases were children aged 12 years or younger; the introduction of JE vaccination in July 2001 reduced the number of JE cases (84 in the four seasons prior to vs. 49 in the six seasons after, McNemar's test, P = 0.0001). After implementation of the programme, the mean age of infected children increased from 6.3 to 8.0 years (Student's t-test, P = 0.0037), suggesting the need for a catch-up programme.

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