Article
Immunology
Zhuochen Li, Rachel L. Winer, Selly Ba, Marie Pierre Sy, John Lin, Qinghua Feng, Geoffrey S. Gottlieb, Papa Salif Sow, Nancy B. Kiviat, Stephen E. Hawes
Summary: In Senegalese women, HIV-positive women had a lower likelihood of clearing incident HPV infections compared to HIV-negative women, while HIV-2-infected or dually infected women were more likely to clear incident HPV infections than HIV-1-infected women.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Review
Microbiology
Michel Carlos Tommo Tchouaket, Aude Christelle Ka'e, Ezechiel Ngoufack Jagni Semengue, Samuel Martin Sosso, Rachel Kamgaing Simo, Bouba Yagai, Alex Durand Nka, Collins Ambe Chenwi, Aissatou Abba, Nadine Fainguem, Carlo-Federico Perno, Vittorio Colizzi, Joseph Fokam
Summary: This systematic review aimed to identify HR-HPV genotypes and their associated factors among women in Sub-Saharan Africa (SSA). The overall pooled prevalence of HR-HPV genotypes in SSA was 55.13%, with a higher prevalence of 75.51% among HIV-positive women. The most commonly reported risk factors associated with HR-HPV infection were HIV infection, multiple sexual partners, and young age. These findings highlight the need for revised vaccination policies to prevent HR-HPV infections.
Article
Multidisciplinary Sciences
Mwiza Gideon Singini, Freddy Sitas, Debbie Bradshaw, Wenlong Carl Chen, Melitah Motlhale, Abram Bunya Kamiza, Chantal Babb de Villiers, Cathryn M. Lewis, Christopher G. Mathew, Tim Waterboer, Robert Newton, Mazvita Muchengeti, Elvira Singh
Summary: In black South African women, the risks factors for cervical cancer were ranked in order of priority as being HIV positive, having lower educational attainment, higher parity, using hormonal contraceptives, heavy alcohol consumption, current smoking, and living in rural areas.
Article
Virology
Charbell M. H. Kury, Gabriela R. Guimaraes, Cinthia G. Leandro, Lorena A. Fernandes, Paulo Ricardo T. Silva, Tania Cristina M. B. Petraglia, Oswaldo G. Cruz, Rodrigo da Costa Carneiro, Silvia M. B. Cavalcanti
Summary: The human immunodeficiency virus (HIV) increases the susceptibility to human papillomavirus (HPV) infection in women. A city in Brazil implemented quadrivalent HPV vaccine (4vHPV) for women living with HIV (WLWH) before the public vaccination program. A prospective cohort study was conducted to characterize the genomic diversity and predictors of HPV infection in WLWH. Age, marital status, number of children, number of sexual partners, and CD4 count were identified as protective factors against HPV infection. The use of 4vHPV is beneficial for this population and should be recommended at an age from 26 to 45 years as part of the public vaccination program.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Oncology
Simon P. Boni, Vanessa Tenet, Apollinaire Horo, Danielle A. M. Heideman, Maaike C. G. Bleeker, Aristophane Tanon, Boston Mian, Isidore D. Mohenou, Didier K. Ekouevi, Tarik Gheit, Judith Didi-Kouko Coulibaly, Boris K. Tchounga, Innocent Adoubi, Gary M. Clifford, Antoine Jaquet, IeDEA West Africa Collaboration
Summary: This study investigated the distribution of high-risk HPV in cervical cancer among women in Cote d'Ivoire. The study confirmed the significant role of HPV16/18 in cervical cancer in this region and suggested the expansion of HPV16/18 vaccination programs regardless of HIV status. Additionally, vaccines targeting other high-risk HPV types could further decrease the incidence of cervical cancer.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Health Care Sciences & Services
Leticia Munoz-Hernando, Reyes Oliver-Perez, Victoria Bravo-Violeta, Alejandro Olloqui, Belen Parte-Izquierdo, Cristina Almansa-Gonzalez, Rocio Bermejo-Martinez, Ana Belen Bolivar-De Miguel, Alvaro Diez, Jose Miguel Seoane-Ruiz, Lucia Parrilla-Rubio, Alvaro Tejerizo-Garcia
Summary: This study analyzed the prevalence of anal high-risk HPV infection and abnormal anal cytology in women living with HIV, finding that concomitant HR-HPV cervical infection is the main predictor of HR-HPV anal infection.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Review
Geriatrics & Gerontology
SeyedAhmad SeyedAlinaghi, Morteza Ghayomzadeh, Pegah Mirzapour, Seyed Farzad Maroufi, Zahra Pashaei, Zoha Ali, Marcarious M. Tantuoyir, Narjes Aghaie, Farzin Vahedi, Roghayeh Salmani, Mehrzad MohsseniPour, Kowsar Qaderi, Ramin Shahidi, Akram Peyman, Sanaz Varshochi, Arian Afzalian, Seyede Parmis Maroufi, Esmaeil Mehraeen, Omid Dadras, Daniel Hackett
Summary: People living with HIV are at a higher risk of sarcopenia, which can significantly impact their quality of life and ultimately lead to death. This systematic review explored the prevalence of sarcopenia in this population and identified several factors associated with its development. The findings indicate that age, gender, time since HIV diagnosis, vertebral fractures, drug use, and gamma-glutamyl transferase level are promoting factors, while higher education, employment, physical exercise, calf circumference, and gait speed are protective factors against sarcopenia.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Medicine, General & Internal
Benedicta N. Nkeh-Chungag, Nandu Goswami, Godwill A. Engwa, Constance R. Sewani-Rusike, Vuyolwethu Mbombela, Ingrid Webster, Patrick De Boever, Harald H. Kessler, Evelyn Stelzl, Hans Strijdom
Summary: Limited information is available on the effect of antiretroviral treatment (ART) on vascular function in South Africans of African descent living with human immunodeficiency virus (HIV). This study found that ART was associated with cardiovascular risk factors, particularly dyslipidaemia, in hypertensive South Africans of African ancestry with HIV. However, ART was not associated with endothelial dysfunction, and flow-mediated dilatation was positively associated with CD4 count in HIV-positive participants on ART.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Virology
Ongeziwe Taku, Zizipho Z. A. Mbulawa, Keletso Phohlo, Mirta Garcia-Jardon, Charles B. Businge, Anna-Lise Williamson
Summary: South African women in the Eastern Cape province have a high prevalence of HPV infection in CIN, especially in HIV-positive individuals. The study found a higher rate of multiple HPV types in HIV-positive women and identified common HPV genotypes in CIN2 and CIN3 cases. The nonavalent HPV vaccine could offer some benefits in preventing CIN2 and CIN3 in both HIV-negative and HIV-positive women, although complete protection may not be guaranteed.
Article
Biotechnology & Applied Microbiology
Charbell Miguel Haddad Kury, Katia Cristina Da Silva Santos, Fernanda Nahoum Carestiato, Gabriela Rapozo, Cinthia Guimaraes Leandro, Lorena Abreu Fernandes, Paulo Ricardo Telles Silva, Mauro Romero Leal Passos, Oswaldo Goncalves Cruz, Silvia Maria Baeta Cavalcanti
Summary: This study analyzed the prevalence of HPV infection in HIV-positive women in Brazil, with a total prevalence of 36%. The majority of HPV types found were included in 4vHPV, indicating potential vaccine effectiveness. Age less than 45 years was identified as a risk factor for infection.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Virology
Cremildo Maueia, Alltalents Murahwa, Alice Manjate, Soren Andersson, Jahit Sacarlal, Darlene Kenga, Tufaria Mussa, Anna-Lise Williamson
Summary: This study demonstrates a high prevalence of HPV infection in women from Maputo, Mozambique, with HIV-positive women having the highest HPV prevalence and being more susceptible to multiple HPV types. High-risk genotypes were the most commonly found.
Article
Infectious Diseases
Kahasit Gebrehiwet, Endalkchew Biranu, Wondatir Nigatu, Atsbeha Gebreegziabher, Kassu Desta
Summary: This study assessed the prevalence and associated risk factors of hepatitis B virus (HBV), human immunodeficiency virus (HIV), and tuberculosis (TB) among individuals with presumptive pulmonary tuberculosis in Addis Ababa, Ethiopia. The findings suggest that HBV, HIV, and TB are still significant public health issues that require awareness and health education on risky behaviors and transmission.
INFECTION AND DRUG RESISTANCE
(2023)
Article
Medicine, General & Internal
Yan-Hua Chen, Tzu-Ming Jao, Yow-Ling Shiue, I-Jung Feng, Ping- Hsu
Summary: This study aimed to investigate the prevalence of Candida esophagitis (CE) among HIV-negative individuals and determine the risk factors predicting CE. The study found that older age, chronic kidney disease, alcohol consumption, and steroid use were independent risk factors for CE development.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Surgery
Gabrielle G. Massey, Joseph M. Firriolo, Laura C. Nuzzi, Tannishtha Pramanick, Shannon M. Malloy, Amy D. DiVasta, Brian I. Labow
Summary: This study found that overweight or obesity, racial or ethnic minority status, early menarche, and patient-reported gynecologic or endocrine complaints were all positively associated with macromastia severity. Awareness of these factors can empower physicians to identify and address modifiable risk factors to prevent progression to more severe disease.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Article
Public, Environmental & Occupational Health
Ray M. Merrill, Elizabeth N. Williams, Heidi Fuhriman
Summary: Women with HIV risk behavior are more likely to pursue Pap, HPV, and HIV testing, with the strongest association found for HIV testing and the weakest for Pap testing after adjusting for selected variables. HIV risk behavior correlates significantly with several variables, which are in turn associated with testing outcomes. However, there is no direct association between HIV risk behavior and HPV vaccination.
JOURNAL OF WOMENS HEALTH
(2021)
Article
Environmental Sciences
Kim Gruetzmacher, William B. Karesh, John H. Amuasi, Adnan Arshad, Andrew Farlow, Sabine Gabrysch, Jens Jetzkowitz, Susan Lieberman, Clare Palmer, Andrea S. Winkler, Chris Walzer
Summary: The One Health approach emphasizes the interconnectedness of human health, non-human animal health, and ecosystem health, providing key guidance for future health. The outbreak of COVID-19 has shown the high cost of inaction, highlighting the importance of taking action now.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Nutrition & Dietetics
Jillian L. Waid, Sheela S. Sinharoy, Masum Ali, Md Mashud Alam, Amanda S. Wendt, Sabine Gabrysch
Summary: Bangladesh has seen significant improvements in child nutrition over the past few decades, with key drivers including child care practices, household diets, and income levels. These improvements highlight the importance of nutrition-specific and nutrition-sensitive interventions to reduce child undernutrition, particularly during the critical first 1000 days of life.
JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Andrea U. Seiermann, Hudaalrahman Al-Mufti, Jillian L. Waid, Amanda S. Wendt, Shafinaz Sobhan, Sabine Gabrysch
Summary: In rural Bangladesh, pregnant Muslim women tend to fast regularly during Ramadan and believe it has positive health effects on both mother and unborn child. Research indicates that Muslim women have more diverse diets during Ramadan, with increased consumption of pulses, dairy, fruit, and large fish. Dietary diversity tends to improve to a lesser extent on non-fasting days during Ramadan.
MATERNAL AND CHILD NUTRITION
(2021)
Article
Multidisciplinary Sciences
Charlene Adaken, Janet T. Scott, Raman Sharma, Robin Gopal, Steven Dicks, Saidia Niazi, Samreen Ijaz, Tansy Edwards, Catherine C. Smith, Christine P. Cole, Philip Kamara, Osman Kargbo, Heidi A. Doughty, Johan van Griensven, Peter W. Horby, Sahr M. Gevao, Foday Sahr, Richard J. Dimelow, Richard S. Tedder, Malcolm G. Semple, William A. Paxton, Georgios Pollakis
Summary: Neutralizing antibody function is crucial for vaccine and therapy efficacy. In this study, a wide spectrum of antibody responses in healthy survivors of the Sierra Leone EBOV outbreak was described, with pseudo-particle virus-neutralizing antibodies correlating with total anti-EBOV reactivity. A pharmacodynamic model identified a decay half-life and doubling time in survivors, suggesting that EBOV antibody reactivity declines over time after recovery. Vigilant follow-up and possible vaccine immunization for de novo antigenic stimulation should be considered to prevent EBOV viral recrudescence in recovering individuals.
Article
Green & Sustainable Science & Technology
Ipsita Sutradhar, Meredith Jackson-deGraffenried, Sayema Akter, Shannon A. McMahon, Jillian L. Waid, Hans-Peter Schmidt, Amanda S. Wendt, Sabine Gabrysch
Summary: The study found that cow urine-enriched biochar fertilizer was preferred over human urine-enriched biochar in Bangladesh, as cow urine was seen as cleaner and socially acceptable. The research showed that biochar-based fertilizer could increase crop yields, cost less, utilize readily available natural materials, improve crop quality, and strengthen social and financial capital. Farmers were motivated to adopt this technology due to its low risks and perceived benefits, indicating strong potential for scaling up in Bangladesh.
ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY
(2021)
Article
Public, Environmental & Occupational Health
Sarah Dupuis, Monique Hennink, Amanda S. Wendt, Jillian L. Waid, Md Abul Kalam, Sabine Gabrysch, Sheela S. Sinharoy
Summary: This study developed a novel framework to describe a pathway to empowerment among female participants in an HFP intervention, as implemented in the FAARM trial. These results have implications for the design of future nutrition-sensitive agriculture interventions, which should prioritize opportunities to increase empowerment and mitigate the barriers identified in our study.
Article
Toxicology
Nicholas N. A. Kyei, Benedikt Cramer, Hans-Ulrich Humpf, Gisela H. Degen, Nurshad Ali, Sabine Gabrysch
Summary: This study investigates the exposure of 439 pregnant women in rural Bangladesh to 35 mycotoxins and their corresponding health risks and finds that exposure to multiple mycotoxins during early pregnancy is widespread in this rural community and represents a potential health risk for mothers and their offspring.
ARCHIVES OF TOXICOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Shafinaz Sobhan, Anna A. Mueller-Hauser, Tarique Md Nurul Huda, Jillian L. Waid, Om Prasad Gautam, Giorgia Gon, Amanda S. Wendt, Sabine Gabrysch
Summary: This study successfully integrated a food hygiene intervention into a nutrition-sensitive agriculture trial in rural Bangladesh, achieving satisfactory participation and uptake of promoted behaviors.
Article
Public, Environmental & Occupational Health
Anna A. Mueller-Hauser, Shafinaz Sobhan, Tarique Md. Nurul Huda, Jillian L. Waid, Amanda S. Wendt, Mohammad Aminul Islam, Mahbubur Rahman, Sabine Gabrysch
Summary: Microbial contamination in complementary foods can be reduced by practicing improved handwashing and food hygiene behaviors. This study found that handwashing with soap at critical times and fresh preparation of food before feeding were strongly associated with reduced odds of food contamination. On the other hand, reheating of stored food, safe food storage, and cleanliness of feeding utensils showed weak evidence in reducing contamination. It was found that a combination of multiple food hygiene behaviors had a greater impact on reducing contamination compared to single practices.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2022)
Article
Development Studies
Jillian L. Waid, Amanda S. Wendt, Sheela S. Sinharoy, Abdul Kader, Sabine Gabrysch
Summary: Nutrition-sensitive agricultural programs have the potential to improve women's and children's nutrition, along with women's empowerment. A study conducted in rural Bangladesh evaluated the impact of a three-year homestead food production program on women's and men's agency using the project-level Women's Empowerment in Agriculture Index (pro-WEAI). The results showed that women in the intervention group had higher levels of agency compared to the control group, driven by intrinsic and collective agency.
Article
Toxicology
Nicholas N. A. Kyei, Jillian L. Waid, Nurshad Ali, Benedikt Cramer, Hans-Ulrich Humpf, Sabine Gabrysch
Summary: Limited and inconsistent evidence suggests a potential link between mycotoxins and adverse birth outcomes. This study examines the role of maternal dietary exposure to multiple mycotoxins in the development of adverse pregnancy and birth outcomes. The findings indicate that exposure to OTA is associated with higher odds of low birth weight babies.
ARCHIVES OF TOXICOLOGY
(2023)
Article
Nutrition & Dietetics
Nathalie J. Lambrecht, Jillian L. Waid, Amanda S. Wendt, Shafinaz Sobhan, Abdul Kader, Sabine Gabrysch
Summary: Women and children in Bangladesh suffer from micronutrient deficiencies. A 3-year Homestead Food Production (HFP) intervention was conducted to improve poultry production and increase egg consumption among women and children. The intervention resulted in increased poultry ownership and egg production, as well as higher odds of women and children consuming eggs.
MATERNAL AND CHILD NUTRITION
(2023)
Article
Genetics & Heredity
Amanda S. Wendt, Joaquin Brintrup, Jillian L. Waid, Abdul Kader, Nathalie J. Lambrecht, Sabine Gabrysch
Summary: The prevalence of alpha thalassemia is high among women and children in rural Sylhet, Bangladesh, higher than all other identified hemoglobinopathies combined. Therefore, future research on inherited blood disorders in Bangladesh should include estimates of alpha thalassemia to raise public health awareness and facilitate couples counseling.
ORPHANET JOURNAL OF RARE DISEASES
(2023)
Article
Environmental Sciences
Sophie Gepp, Laura Jung, Katharina Wabnitz, Frederick Schneider, Friederike v Gierke, Hannah Otto, Sylvia Hartmann, Theresa Gemke, Christian Schulz, Sabine Gabrysch, Marischa Fast, Eva-Maria Schwienhorst-Stich
Summary: The planetary crises call for health professionals to understand the connection between health and environmental changes, and to reduce ecological harm and promote positive change. However, their education and training in these aspects are lacking. This viewpoint presents findings from the evaluation of the Planetary Health Academy in Germany, which was the first online lecture series for transformative planetary health education. The survey results provide insights for future transformative education efforts and suggest that education, combined with networking and movement building, can contribute to taking actions to mitigate global environmental changes.
LANCET PLANETARY HEALTH
(2023)
Article
Immunology
Jacqueline K. Lim, Mabel Carabali, Tansy Edwards, Ahmed Barro, Jung-Seok Lee, Desire Dahourou, Kang Sung Lee, Teguewende Nikiema, Mee Young Shin, Emmanuel Bonnet, Therese Kagone, Losseni Kaba, Suk Namkung, Paul-Andre Som, Jae Seung Yang, Valery Ridde, In-Kyu Yoon, Neal Alexander, Yaro Seydou
Summary: This study conducted 4 consecutive age-stratified longitudinal serologic surveys in Burkina Faso, revealing a high force of infection (FOI) for dengue, which could provide valuable support for decision-making regarding control and preventive measures for dengue.
EMERGING INFECTIOUS DISEASES
(2021)