标题
Adaptive trial designs: a review of barriers and opportunities
作者
关键词
-
出版物
Trials
Volume 13, Issue 1, Pages -
出版商
Springer Nature
发表日期
2012-08-23
DOI
10.1186/1745-6215-13-145
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Rest versus exercise as treatment for patients with low back pain and Modic changes. a randomized controlled clinical trial
- (2012) Rikke K Jensen et al. BMC Medicine
- Efficacy and tolerability of rizatriptan in pediatric migraineurs: Results from a randomized, double-blind, placebo-controlled trial using a novel adaptive enrichment design
- (2012) Tony W Ho et al. CEPHALALGIA
- Planning and Executing Response-Adaptive Learn-Phase Clinical Trials: 1. The Process
- (2012) Parvin Fardipour et al. DRUG INFORMATION JOURNAL
- Adaptive Randomization for Clinical Trials
- (2012) William F. Rosenberger et al. Journal of Biopharmaceutical Statistics
- Design Issues in Randomized Phase II/III Trials
- (2012) Edward L. Korn et al. JOURNAL OF CLINICAL ONCOLOGY
- NeuroNEXT: accelerating drug development in neurology
- (2012) The Lancet Neurology LANCET NEUROLOGY
- Potential of adaptive clinical trial designs in pharmacogenetic research
- (2012) Frederieke H van der Baan et al. PHARMACOGENOMICS
- The covariate-adaptive biased coin design for balancing clinical trials in the presence of prognostic factors
- (2011) A. Baldi Antognini et al. BIOMETRIKA
- A point-of-care clinical trial comparing insulin administered using a sliding scale versus a weight-based regimen
- (2011) Louis D Fiore et al. Clinical Trials
- Phase I study of continuous MKC-1 in patients with advanced or metastatic solid malignancies using the modified Time-to-Event Continual Reassessment Method (TITE-CRM) dose escalation design
- (2011) Amye Tevaarwerk et al. INVESTIGATIONAL NEW DRUGS
- FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
- (2011) Thierry Conroy et al. NEW ENGLAND JOURNAL OF MEDICINE
- Benefits, challenges and obstacles of adaptive clinical trial designs
- (2011) Shein-Chung Chow et al. Orphanet Journal of Rare Diseases
- A Bayesian response-adaptive covariate-balanced randomization design with application to a leukemia clinical trial
- (2011) Ying Yuan et al. STATISTICS IN MEDICINE
- Safety and Tolerability of Deferoxamine Mesylate in Patients With Acute Intracerebral Hemorrhage
- (2011) Magdy Selim et al. STROKE
- Efficiency Perspectives on Adaptive Designs in Stroke Clinical Trials
- (2011) Ken Cheung et al. STROKE
- Internal pilots for observational studies
- (2010) Matthew J. Gurka et al. BIOMETRICAL JOURNAL
- A simulation study for comparing testing statistics in response-adaptive randomization
- (2010) Xuemin Gu et al. BMC Medical Research Methodology
- Enrichment of Clinical Study Populations
- (2010) R Temple CLINICAL PHARMACOLOGY & THERAPEUTICS
- Combining an Internal Pilot with an Interim Analysis for Single Degree of Freedom Tests
- (2010) John A. Kairalla et al. COMMUNICATIONS IN STATISTICS-THEORY AND METHODS
- Adaptive Methods: Telling “The Rest of the Story”
- (2010) Scott S. Emerson et al. Journal of Biopharmaceutical Statistics
- Outcome-Adaptive Randomization: Is It Useful?
- (2010) Edward L. Korn et al. JOURNAL OF CLINICAL ONCOLOGY
- Seamless phase II/III designs
- (2010) Nigel Stallard et al. STATISTICAL METHODS IN MEDICAL RESEARCH
- Adaptive increase in sample size when interim results are promising: A practical guide with examples
- (2010) Cyrus R. Mehta et al. STATISTICS IN MEDICINE
- Comparative effectiveness research: Policy context, methods development and research infrastructure
- (2010) Sean R. Tunis et al. STATISTICS IN MEDICINE
- The Bias Issue Under the Complete Null With Response Adaptive Randomization: Commentary on “Adaptive and Model-Based Dose-Ranging Trials: Quantitative Evaluation and Recommendation”
- (2010) Sue-Jane Wang Statistics in Biopharmaceutical Research
- Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III
- (2009) Petra Kaufmann et al. ANNALS OF NEUROLOGY
- Adaptive patient enrichment designs in therapeutic trials
- (2009) Sue-Jane Wang et al. BIOMETRICAL JOURNAL
- Sample size re-estimation in clinical trials
- (2009) Michael A. Proschan BIOMETRICAL JOURNAL
- High-Dose Lovastatin for Acute Ischemic Stroke: Results of the Phase I Dose Escalation Neuroprotection with Statin Therapy for Acute Recovery Trial (NeuSTART)
- (2009) Mitchell S.V. Elkind et al. CEREBROVASCULAR DISEASES
- Dose Escalation Methods in Phase I Cancer Clinical Trials
- (2009) Christophe Le Tourneau et al. JNCI-Journal of the National Cancer Institute
- Blinded sample size recalculation for clinical trials with normal data and baseline adjusted analysis
- (2009) Tim Friede et al. PHARMACEUTICAL STATISTICS
- Handling Covariates in the Design of Clinical Trials
- (2009) William F. Rosenberger et al. STATISTICAL SCIENCE
- Adaptive designs for confirmatory clinical trials
- (2009) Frank Bretz et al. STATISTICS IN MEDICINE
- Group Sequential and Adaptive Designs - A Review of Basic Concepts and Points of Discussion
- (2008) Marc Vandemeulebroecke BIOMETRICAL JOURNAL
- Adaptive Clinical Trials
- (2008) Christopher S Coffey et al. Drugs in research & development
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More