Article
Medicine, General & Internal
Bruno Giraudeau, Agnes Caille, Sandra M. Eldridge, Charles Weijer, Merrick Zwarenstein, Monica Taljaard
Summary: Pragmatic trials aim to generate evidence to inform decisions, but heterogeneity in patient characteristics and other factors can affect outcomes. Different sources of heterogeneity in trials should be managed, and some heterogeneity can be acceptable. Heterogeneity in centers and patients should be welcomed, control interventions should reflect usual care, and flexibility in interventions should be allowed. Objective outcomes and intention-to-treat analysis should be favored. Process analyses can provide further understanding of trial results.
Article
Psychiatry
Gemma Lombardi, Elena Chipi, Domenico Arenella, Ambra Fiorani, Giovanni Battista Frisoni, Simona Linarello, Chiara Montanucci, Cristina Muscio, Irene Pacifico, Silvia Pelizzari, Daniela Perani, Fabrizio Piras, Luca Rozzini, Sandro Sorbi, Gianfranco Spalletta, Fabrizio Tagliavini, Pietro Tiraboschi, Lucilla Parnetti, Graziella Filippini
Summary: This study aimed to evaluate the effectiveness of an educational intervention for Italian family physicians in improving timely detection and management of cognitive decline. The results showed an overall improvement in diagnostic procedures and patient management by family physicians, but non-pharmacological interventions and support services were underrepresented even after the intervention.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Medicine, General & Internal
Michael Rimmer, Nagla Elfaki, Cheryl Dunlop, Damien Coleburt, Neil Cowan, Olivia Raglan, Jhia Jiat Teh, Maria Fisher, Sarah Mcrobbie, Nilaani Murugesu, Meera Ramcharn, Mohamed Abdelrahman, Yazid Jibrel, Matthew Wood, William Parry-Smith, Bassel H. Al Wattar
Summary: The Web-Ed trial aims to evaluate the educational benefits, feasibility, and acceptability of web-based virtual journal clubs (JC) compared with traditional face-to-face ones. This multicentre pragmatic parallel-group randomized trial will enrol qualified doctors or medical students in the UK National Health Service (NHS) and assess their knowledge acquisition and retention using standardized multiple-choice questions. The trial results will be published in peer-reviewed journals and presented at scientific conferences.
Article
Medicine, Research & Experimental
Rami A. Alyami, Rebecca Simpson, Phillip Oliver, Steven A. Julious
Summary: In this study, a simple letter sent from the family doctor to parents of children with asthma during the school holidays increased prescriptions by 30% in August and reduced medical contacts from September to December. Informing GP practices of this intervention may improve the implementation of asthma preventer medication and increase prescription uptake.
Review
Geriatrics & Gerontology
Lenique K. L. Huggins, Se Hee Min, Chelsea-Ann Dennis, Truls Ostbye, Kimberly S. Johnson, Hanzhang Xu
Summary: Existing educational interventions promoting dementia knowledge mainly focus on racial/ethnic minority groups in the United States and the UK. The interventions target Asian/Pacific Islander, Black, and Hispanic groups, with varied delivery modes including workshops and online videos. These interventions show positive impacts on improving dementia knowledge and attitudes, but overall quality is relatively low.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Article
Geriatrics & Gerontology
Maria P. Aranda, Rosa Baier, Ladson Hinton, Katherine D. Peak, Jonathan D. Jackson, Peggye Dilworth-Anderson, Laura N. Gitlin, Eric Jutkowitz, Ana R. Quinones
Summary: Inequities in brain health, economic costs, and evidence base for dementia care persist. Achieving health equity in dementia care involves ensuring affected populations' full participation in and benefit from clinical research. Embedding proven interventions in real-world conditions and healthcare systems can enhance dementia care, resource utilization, and exam effectiveness. Developing ePCT research designs for non-pharmacological dementia care interventions requires careful considerations and frameworks for health equity readiness.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Health Care Sciences & Services
Kelsey L. Grantham, Andrew B. Forbes, Richard Hooper, Jessica Kasza
Summary: This article introduces the 'staircase' design, which is a new experimental design method based on the zigzag pattern of steps. It can alleviate the burden on participating clusters, promote trial involvement, and reduce attrition. Although there is a lack of consistent methodology, we provide variance expressions for sample size and power calculations for the staircase designs.
STATISTICAL METHODS IN MEDICAL RESEARCH
(2023)
Article
Medicine, General & Internal
Frank R. Lin, James R. Pike, Marilyn S. Albert, Michelle Arnold, Sheila Burgard, Theresa Chisolm, David Couper, Jennifer A. Deal, Adele M. Goman, Nancy W. Glynn, Theresa Gmelin, Lisa Gravens-Mueller, Kathleen M. Hayden, Alison R. Huang, David Knopman, Christine M. Mitchell, Thomas Mosley, James S. Pankow, Nicholas S. Reed, Victoria Sanchez, Jennifer A. Schrack, B. Gwen Windham, ACHIEVE Collaborative Res Grp
Summary: This study aimed to investigate the impact of a hearing intervention on cognitive decline in older adults. The results showed that the hearing intervention did not reduce cognitive decline over 3 years in the total sample. However, a sensitivity analysis indicated that the hearing intervention might reduce cognitive change in populations at increased risk for cognitive decline.
Review
Nursing
Ita Daryanti Saragih, Santo Imanuel Tonapa, Tien-Lung Sun, Lin Chia-Ju, Bih-O Lee
Summary: Robotic care interventions show positive effects on anxiety, cognitive function, depression, sleep duration, and quality of life among patients with dementia. Further studies are needed to confirm the effects of robotic care on anxiety and explore potential negative outcomes.
JOURNAL OF CLINICAL NURSING
(2021)
Review
Nursing
Prativa Dhakal, Debra K. Creedy, Jenny Gamble, Elizabeth Newnham, Rhona McInnes
Summary: This systematic review evaluated the impact of educational interventions on enhancing the knowledge and attitudes of midwives, nurses, and midwifery/nursing students towards respectful maternity care. The study found that educational interventions can improve healthcare professionals' knowledge and perceptions of respectful care, enhance communication with women, and reduce women's experience of disrespect and abuse. However, the variation in intervention content and delivery hindered robust conclusions. Continuous education and inclusion of other healthcare providers and managerial staff are needed to promote respectful care.
NURSE EDUCATION IN PRACTICE
(2022)
Article
Communication
Gabriela Ferreira, Andre Carvalho, M. Graca Pereira
Summary: Diabetic foot is a serious complication of diabetes, and foot ulcer recurrence is related to poor foot care. Educational programs can promote knowledge and self-care behaviors, reduce ulcerative complications, and improve quality of life. This study will analyze the impact of two different educational strategies on adherence, knowledge, and patients' perception of foot health.
HEALTH COMMUNICATION
(2023)
Review
Health Care Sciences & Services
Sandra Shi, Emily A. Largent, Ellen McCreedy, Susan L. Mitchell
Summary: Advance care planning (ACP) is crucial for dementia patients, but its clinical usage remains limited. Embedded pragmatic clinical trials (ePCTs) can help integrate evidence-based ACP interventions into real-world settings. However, conducting rigorous ePCTs for dementia patients presents methodological challenges. In this study, a framework for constructing these research studies is described, with a focus on participant identification, recruitment, intervention implementation, and outcome selection. The approaches from three published trials are discussed, highlighting how challenges were overcome through tradeoffs in study design. Future directions for advancing ePCTs for ACP among dementia patients are also proposed.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2023)
Article
Medicine, General & Internal
Grant M. Russell, Katrina Long, Virginia Lewis, Joanne C. Enticott, Nilakshi Gunatillaka, I--Hao Cheng, Geraldine Marsh, Shiva Vasi, Jenny Advocat, Shoko Saito, Hyun Song, Sue Casey, Mitchell Smith, Mark F. Harris
Summary: The study aimed to investigate whether primary care outreach facilitation could enhance the quality of care for general practice patients from refugee backgrounds. The results showed that the intervention led to an increase in the proportion of refugee patients receiving Medicare-billed health assessments, but had limited impact on other aspects of care.
MEDICAL JOURNAL OF AUSTRALIA
(2021)
Article
Public, Environmental & Occupational Health
Nienke van Wezel, Iris van der Heide, Walter L. J. M. Deville, Emine Kayan Acun, Julie H. C. M. Meerveld, Peter Spreeuwenberg, Marco M. Blom, Anneke L. Francke
Summary: This study examined the effects of an educational peer-group intervention on family caregivers with Turkish or Moroccan immigrant backgrounds, showing that this intervention can improve their knowledge about dementia and increase support from home-care staff. Offering peer-group-based education about dementia is crucial for multicultural dementia care.
PATIENT EDUCATION AND COUNSELING
(2021)
Article
Education & Educational Research
Antti Rajala, Michael Cole, Moises Esteban-Guitart
Summary: This article examines the methodological foundations for a utopian methodology in Design-Based Intervention Research (DBR) and proposes principles for its implementation. The author illustrates the broad usefulness of this methodology through examples.
JOURNAL OF THE LEARNING SCIENCES
(2023)
Article
Health Care Sciences & Services
Kethakie Lamahewa, Rammya Mathew, Steve Iliffe, Jane Wilcock, Jill Manthorpe, Elizabeth L. Sampson, Nathan Davies
HEALTH EXPECTATIONS
(2018)
Article
Geriatrics & Gerontology
Nathan Davies, Steve Iliffe, Jenny Hopwood, Nina Walker, Jamie Ross, Greta Rait, Kate Walters
AGING & MENTAL HEALTH
(2020)
Article
Environmental Sciences
Gesa Czwikla, Filip Boen, Derek G. Cook, Johan de Jong, Tess Harris, Lisa K. Hilz, Steve Iliffe, Richard Morris, Saskia Muellmann, Denise A. Peels, Claudia R. Pischke, Benjamin Schuez, Martin Stevens, Frank J. van Lenthe, Julie Vanderlinden, Gabriele Bolte
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2019)
Article
Geriatrics & Gerontology
K. Kharicha, J. Manthorpe, S. Iliffe, C. A. Chew-Graham, M. Cattan, C. Goodman, M. Kirby-Barr, J. H. Whitehouse, K. Walters
Summary: Engaging with older people who self-identify as lonely can help professionals understand how they cope with loneliness. The study aimed to explore how lonely older people in England manage their experiences of loneliness, finding that participants utilized a range of strategies to alleviate distress.
AGING & MENTAL HEALTH
(2021)
Article
Nutrition & Dietetics
Gotaro Kojima, Steve Iliffe, Stephen Jivraj, Kate Walters
Review
Rehabilitation
Marlot Kruisbrink, Rik Crutzen, Gertrudis I. J. M. Kempen, Kim Delbaere, Ton Ambergen, Kei Long Cheung, Denise Kendrick, Steve Iliffe, G. A. Rixt Zijlstra
Summary: Based on a systematic review of scientific literature databases, it was found that components such as meditation, holistic exercises, and body awareness were more effective in reducing fear of falling in older adults, while interventions with self-monitoring, balance exercises, or tailoring were less effective. These findings can help in designing and optimizing treatments to reduce FoF.
DISABILITY AND REHABILITATION
(2022)
Article
Public, Environmental & Occupational Health
E. Orton, N. Lafond, D. A. Skelton, C. Coupland, J. R. F. Gladman, S. Iliffe, P. A. Logan, T. Masud, C. Timblin, S. Timmons, D. Kendrick
Summary: This study aimed to examine the implementation fidelity of the FaME programme when delivered in the community in order to inform quality improvement strategies. The research found that FaME programmes can be implemented with a high degree of fidelity in the 'real world', although important deviations were identified. Interviews with FaME instructors helped to explain why certain elements of programme content and quality were not delivered.
Article
Primary Health Care
Conceicao Balsinha, Steve Iliffe, Sonia Dias, Alexandre Freitas, Filipa F. Barreiros, Manuel Goncalves-Pereira
Summary: This study aims to explore the barriers to the implementation of the Portuguese Dementia Strategy by primary care teams from the perspectives of service users and professionals. The findings identified several system barriers and individual barriers that hindered users' access to dementia services. Enhanced competence in dementia and nurse-led systematic care, along with better community support, are necessary to improve the quality of life for people with dementia.
PRIMARY HEALTH CARE RESEARCH AND DEVELOPMENT
(2022)
Article
Gerontology
Laura Cole, Vari M. Drennan, Jill Manthorpe, Eleni Hatzidimitriadou, Steve Iliffe
Summary: This study investigated the experiences of intimate continence care for people living with dementia and their family members, and whether they viewed this as impacting on their relationship. The findings showed that attitudes towards providing intimate continence care varied among carers, with some taking a task-focused approach and others feeling disgust and distress. However, some carers felt that the care and support received from professionals were insufficient, leading to additional stress and negatively affecting the family dyad relationship.
DEMENTIA-INTERNATIONAL JOURNAL OF SOCIAL RESEARCH AND PRACTICE
(2022)
Article
Health Policy & Services
Rachael Frost, Kate Walters, Jane Wilcock, Louise Robinson, Karen Harrison Dening, Martin Knapp, Louise Allan, Greta Rait
Summary: The study found significant variation in the types of post-diagnostic dementia support provided in England, with information, caregiver assessments, and dementia navigation being common services usually delivered by the voluntary sector or local authorities. Integrated pathways of care were seen as important to avoid gaps or overlaps in service coverage. Despite an increasingly diverse population, few areas reported providing dementia health services specifically for BME populations.
JOURNAL OF INTEGRATED CARE
(2021)
Review
Public, Environmental & Occupational Health
Rachael Frost, Greta Rait, Alison Wheatley, Jane Wilcock, Louise Robinson, Karen Harrison Dening, Louise Allan, Sube Banerjee, Jill Manthorpe, Kate Walters
HEALTH & SOCIAL CARE IN THE COMMUNITY
(2020)
Article
Public, Environmental & Occupational Health
Jane Wilcock, Steve Iliffe, Jo Moriarty, Jill Manthorpe
HEALTH & SOCIAL CARE IN THE COMMUNITY
(2020)
Article
Public, Environmental & Occupational Health
Christina Avgerinou, Benjamin Gardner, Kalpa Kharicha, Rachael Frost, Ann Liljas, Rekha Elaswarapu, Jill Manthorpe, Vari M. Drennan, Claire Goodman, Steve Iliffe, Kate Walters
HEALTH & SOCIAL CARE IN THE COMMUNITY
(2019)
Article
Gerontology
Steve Iliffe, Jane Wilcock, Michal Synek, Radek Carboch, Dana Hradcova, Iva Holmerova
DEMENTIA-INTERNATIONAL JOURNAL OF SOCIAL RESEARCH AND PRACTICE
(2019)